Colorectal Cancer Association of Canada - CCAC

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Inflammatory Protein MMP9 May Protect Against Bowel-disease-related Colorectal Cancer

An inflammatory protein called MMP9 may protect against the development of a colorectal cancer associated with chronic inflammatory processes, such as inflammatory bowel disease (IBD), according to a study.

The research, “Epithelial Derived-Matrix Metalloproteinase (MMP9) Exhibits A Novel Defensive Role Of Tumor Suppressor In Colitis Associated Cancer By Activating MMP9-Notch1-ARF-p53 Axis,” was published in the journal Oncotarget.

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