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Advances Come in War on Cancer

[...] CHICAGO—Researchers reported notable advances in the war on cancer over the weekend, including treatments for lung, ovarian and skin cancers, but they cautioned [...]

Roche to present major advances with targeted cancer medicines at ASCO

[...] of cancers. Results could significantly improve the way cancer is treated for patients with inoperable stomach cancer; advanced melanoma; lung and breast cancers. Roche today provided an overview of results from studies that further the compan [...]

‘Microbeads’ May Boost Survival in Advanced Colon Cancer Patients

[...] By Maureen Salamon HealthDay Reporter For advanced colon cancer patients who have developed liver tumors, so-called “radioactive beads” implanted near these tumor [...]

American Cancer Society Colorectal Cancer Guide

[...] cent studies have provided even stronger evidence regarding the ability of aspirin to prevent the growth of polyps. The advantage of these recent studies is that people were randomly selected by the researchers to receive either aspirin or an i [...]

Advancements in Screening for Colorectal Cancer

[...] which a thin, flexible tube—or scope—with a built-in camera is placed through the patient’s rectum and physically advanced through the entire large intestine. The day prior to a colonoscopy, patients undergo a “bowel prep,” which may [...]

New treatments offer better survival and fresh challenges in colorectal cancer

[...] New research details drug therapies in 2009 in Therapeutic Advances in Medical Oncology, published by SAGE Los Angeles, London, New Delhi, Singapore and Washington DC (August 21, 2009 [...]

Curis Announces GDC-0449 Phase I Clinical Data Published in New England Journal of Medicine

[...] Phase I Data in 33 Patients Demonstrates Molecule`s Potential as Treatment for Locally Advanced and Metastatic Basal Cell Carcinoma CAMBRIDGE, Mass.—(Business Wire)— Curis, Inc. (NASDAQ: CRIS), a dru [...]

Clinical benefits and costs of new treatments for advanced colorectal cancer

[...] We selected 9 possible regimens that reflect the benefit of recent advances in treatment of metastatic CRC (Table 1). For this model, we included only intravenous regimens and did not include [...]

Real World Practice Confirms Avastin’s Efficacy and Safety in Advanced Colorectal Cancer

[...] New data from 4,000 patients show that Avastin (bevacizumab rhuMAb-VEGF) enables patients with advanced colorectal cancer (CRC) to live longer without progression of their disease.(1) The results also confirm that Avast [...]

New Advances and Insights in Gastroenterology Presented at College’s 74th Annual Meeting | Reuters

[...] cientific Meeting at the San Diego Convention Center starting Monday, October 26, 2009, to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management. Presentations at th [...]

Cetuximab in the treatment of advanced colorectal cancer - K-ras predicts benefit

[...] indings they reported in Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med. 2008;359:1757-1765. Key research findings * K-ras predicts which patients will ben [...]

Bristol-Myers Squibb Canada commercializes ERBITUX(TM) for advanced colorectal cancer

[...] n to fight this deadly disease. "Cetuximab will give us another chance to extend and improve the lives of patients with advanced colorectal cancer for whom irinotecan-based chemotherapy is no longer effective or tolerated," said Dr. Derek Jonke [...]

Study Suggests Cancer Screening For Patients With Advanced Colon Cancer Provides No Added Benefit

[...] Researchers assessed data on more than 87,000 Medicare patients who were diagnosed with advanced lung, colorectal, pancreatic, gastroesophageal or breast cancer between 1998 and 2005. Another group of more than 8 [...]

OK to Delay CT Colon Screen in Women

[...] California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner Age and sex strongly predicted the presence of advanced neoplasia in patients initially screened for colorectal cancer using CT colonography, since women reached the same [...]

Phase I Dose-Escalation Study of AZD2171 in Advanced Cancers With Liver Metastases

[...] (VEGFR-1, -2, and -3). A phase I study was conducted to assess the safety and tolerability of AZD2171 in patients with advanced cancer and liver metastases. Patients and Methods. Patients with tumors refractory to standard therapies or for whi [...]

Population-Based Assessment of the Surgical Management of Locally Advanced Colorectal Cancer

[...] Evidence-based guidelines recommend multivisceral resection for patients with locally advanced adherent colorectal cancer because it reduces local recurrence and improves survival. However, this procedure can i [...]

Immunochemistry Superior to Guaiac Test in Detecting Colorectal Cancer CME

[...] tality, but the method currently in use is the guaiac test, which has limited sensitivity in detecting colon cancer and advanced disease. The guaiac test is able to detect the peroxidase activity of heme, but because peroxidase is present in se [...]

Treatment Options for Colorectal Cancer

[...] at develops within a polyp can often be cured by removing the polyp at the time of colonoscopy. In colon cancer, a more advanced tumor typically requires surgical removal of the section of the colon containing the tumor with sufficient margins, [...]

A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

[...] o Charles D. Blanke, MD, FACP - British Columbia Cancer Agency AZD2281 and Irinotecan in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer ClinicalTrials.gov Identifier: NCT00535353 This phase I trial is studying the side [...]

New Drug Regimen Shows Clear Benefit for Treating Advanced Colorectal

[...] Initial results from a large, randomized clinical trial for patients with advanced colorectal cancer show that those who received a regimen containing the investigational drug oxaliplatin lived mont [...]

Erbitux Offers Benefit In Some Advanced Colon Cancer

[...] July 21, 2004) - Cetuximab (Erbitux) used with irinotecan offers some benefit for advanced stage colon cancer patients whose disease no longer responds to irinotecan alone. There is no cure for colon cancer [...]

Cetuximab Improves Overall Survival In Advanced Colorectal Cancer

[...] ody which targets the epidermal growth factor receptor (EGFR), significantly improved overall survival in patients with advanced colorectal cancer, according to results from a major study reported at the 2007 Annual Meeting of the American Asso [...]

Smokers with advanced colon cancer may face higher odds of disease recurrence

[...] CHICAGO—People with advanced colon cancer who have smoked cigarettes or used other tobacco products for many years may have an increased risk th [...]

Advance Care Planning in Cancer Care

[...] or comfort care measures near the end of life? Learn more about what the BC Health Authorities are doing in the area of Advance Care Planning. Not in British Columbia? Community Oncology Network members can: Connect by phone by dialing into the [...]

Fighting cancer: Newer drugs offering patients hope

[...] two other universities and approved 60 years ago last month by the U.S. Food and Drug Administration. Thanks in part to advances in genetic science, chemo is becoming more effective and far less grueling, and is transforming treatment for many [...]

ERBITUX™ nOW AVAILABLE IN ONTARIO AND BC FOR PATIENTS WITH ADVANCED COLORECTAL CANCER

[...] ts safety and clinical effectiveness. “There is strong clinical data to support the use of cetuximab in patients with advanced colorectal cancer. Having access to this important option will make an appreciable difference,” explained Dr. Der [...]

Combination of Serrated Polyps, Adenomas Increases Colorectal Cancer Risk

[...] November 1, 2010 (San Antonio, Texas) — The presence of adenomas and advanced serrated polyps (ASP), including sessile serrated polyps and serrated adenomas, indicates an aggressive colorectal [...]

Combination of Serrated Polyps, Adenomas Increases Colorectal Cancer Risk

[...] November 1, 2010 (San Antonio, Texas) — The presence of adenomas and advanced serrated polyps (ASP), including sessile serrated polyps and serrated adenomas, indicates an aggressive colorectal [...]

Houston Colorectal Surgeon Discusses Advanced Robotic Surgery for Cancer Treatment

[...] and 90 percent of patients can be restored to normal health if the cancer is detected and treated in early stages. With advanced robotic surgery, Dr. Haas says surgeons can achieve the highest level of efficiency and precision while improving p [...]

Combination Drug, Chemo May Extend Life of Colon Cancer Patients

[...] By Alan Mozes HealthDay Reporter SUNDAY, June 3 (HealthDay News) — Treating advanced-stage colon cancer patients with a combination of chemotherapy and the tumor-targeting drug Avastin appears to prol [...]

FDA approves new treatment for advanced colorectal cancer

[...] viewed under the FDA’s priority review program that provides an expedited six-month review for drugs that offer major advances in treatment or that provide treatment when no adequate therapy exists. Stivarga is being approved one month ahead [...]

Screening Methods

[...] majority of cases, colorectal cancer is preventable and yet each year in Canada, thousands of people are diagnosed with advanced colorectal cancer. The majority of colorectal cancers begin as benign growths in the lining of the large bowel wall [...]

Yakult Honsha Initiates Perifosine Phase I/II Trial For Colorectal Cancer in Japan

[...] s PI3K/Akt inhibitor, perifosine, in combination with chemotherapeutic agent, capecitabine, in patients with refractory advanced colorectal cancer (CRC). Perifosine is a novel, oral anticancer treatment that inhibits Akt activation in the phosp [...]

Advances aid colon cancer treatment

[...] Colon cancer — the most ignored of the major tumors — has moved into the medical spotlight with new testing advances more acceptable to consumers, two new chemotherapy drugs and a $10-million national advertising campaign featuring [...]

Positive recommendation for Avastin use in advanced or recurrent colorectal cancer in Japan

[...] oday announced that Chugai has received a positive recommendation for the use of Avastin (bevacizumab) in patients with advanced or recurrent colorectal cancer. This recommendation was granted by a consultative expert panel for the Japanese Min [...]

Drug May Prevent Oxaliplatin-Induced Peripheral Neuropathy in Advanced Colon Cancer Patients: Presented at ENS

[...] l antiepileptic drug (AED), can help prevent chronic oxaliplatin-induced peripheral neuropathy (OxIPN) in patients with advanced colon cancer. Advanced colorectal cancer (CRC) is one of the most frequent types of solid organ malignancies in the [...]

Left-sided colorectal neoplasms reduced 10-years postcolonoscopy in community setting | HemOncToday

[...] Colonoscopies performed in the community setting reduced the risk for advanced neoplasms by 67% in the left colon and rectum; however, no risk reduction was noted for advanced neoplasms in the r [...]

Colorectal Cancer Immunotherapy

[...] currently under investigation for colorectal cancer, including cancer vaccines and adoptive cell therapy. Weakness and advantages of each strategy and progress in clinical trials will be described. Examination of previous and ongoing research [...]

Canadian Association of Gastroenterology and the Canadian Digestive Health Foundation: Guidelines on colon cancer screening

[...] sting every two years instead of every year, and we suggest that clinical judgement determine the type of follow-up for advanced adenomas (instead of colonoscopy after three years, as in the AGA guidelines). Stratification of risk of colon canc [...]

Poor, women more likely to have advanced colon cancer, study finds

[...] Ontario's Institute for Evaluative Sciences found that women were seven per cent more likely than men to have signs of advanced disease at the time of diagnosis; the risk for poor individuals was 22 per cent above that of high-income patients. [...]

Racial Differences in Response to Advanced Colon Cancer Treatments

[...] ates and Canada point to another possibility: response differences among blacks to standard chemotherapy treatments for advanced colorectal cancer. The results also suggest that genetic differences in metabolism of chemotherapy drugs may play a [...]

Physicians, scientists: The collaboration advantage

[...] ining Dana-Farber's collaborative approach to patient-oriented research on Friday. The group discussed cancer treatment advances during the Harvard Medical School-affiliated institute's sixth annual Breakfast with the Doctors at a private socia [...]

More Living Longer With Advanced Colon Cancer

[...] ates WEDNESDAY, May 27 (HealthDay News) — Over the past 15 years, the average survival rate for patients battling advanced colorectal cancer has increased dramatically, new research indicates, due in equal measure to the advent of new, po [...]

ACG: Racial Disparities Seen in Colorectal CancerAfrican-Americans have twice the risk of proximal cancer as Asians, advanced cancer as Hispanics

[...] gher incidence rate (21.9 versus 11.4). Of all the groups studied, African-Americans had the highest incidence rates of advanced cancers. In both African-American males and females, the incidence rates were about double compared to those seen i [...]

link to side effects

[...] prevented or corrected by using erythropoietin, or by giving a blood transfusion, both of which have been determined to advance disease progression. Carefully-managed anemia will be overseen by the treating physician so as to either prevent or [...]

New study finds strong association between smoking and flat precancerous polyps

[...] as (precancerous polyps) in the colon and may explain the earlier onset of colorectal cancer in smokers, as well as the advanced stage with which they present when compared to nonsmokers. Flat adenomas are more difficult to detect and have more [...]

HealthWatch: Advancements have made colorectal cancer surgery safer

[...] detection and treatment. How is colorectal cancer treated? The most common treatment for colorectal cancer is surgery. Advancements in minimally invasive (laparoscopic) surgical techniques have made colon cancer surgery much safer and much mor [...]

Decreased incidence is credited to increased screening and awareness, while prevention efforts continue.

[...] take the test online, click here. For a printer-friendly version of the exam you can print out, complete and mail in to ADVANCE click here. This continuing education offering is sponsored by an educational grant from Yale-New Haven Hospital. Le [...]

The Medical Minute: Advances in laparoscopic colorectal surgery

[...] is, Crohn’s disease and diverticulitis, while using smaller points of access to the abdominal cavity. These technical advances have allowed for the surgical cure of diseases through three to five small incisions each of which is typically no [...]

Reducing Waiting Times and Advancing Chronic Disease Strategies: The National Action Plan

[...] Reducing Waiting Times and Advancing Chronic Disease Strategies: The National Action Plan - (Click to download pdf) [...]

Whither Irinotecan?

[...] For four decades, oncologists had a limited choice of drug options to use in treatment of advanced colorectal cancer: fluorouracil (FU), FU, or FU. Researchers were (not) kept busy investigating the unexciting ques [...]

Lilly ImClone Drugs Advance to Final Tests This Year

[...] he final round of tests required for regulatory approval include IMC-1121B, which is being evaluated as a treatment for advanced stomach cancer and breast cancer, and IMC-11F8, a successor to Erbitux, which treats colon, head and neck tumors. A [...]

Oral Targeted Agent Recentin Active in Renal Cell Carcinoma

[...] t inhibitor of vascular endothelial growth factor (VEGF) tyrosine kinases, is active for the treatment of patients with advanced renal cell carcinoma (RCC). The details of this study were presented as a late-breaking abstract at the Joint ECCO [...]

Colorectal cancer survival advantage in MUTYH-associated polyposis

[...] ll as in the mismatch repair genes predisposing to Lynch syndrome, are the causal factors for their respective survival advantages. Furthermore, they write, "the ultimate understanding of the pathogenetic pathways elicited by these respective m [...]

Colorectal cancer survival advantage in MUTYH-associated polyposis

[...] ll as in the mismatch repair genes predisposing to Lynch syndrome, are the causal factors for their respective survival advantages. Furthermore, they write, "the ultimate understanding of the pathogenetic pathways elicited by these respective m [...]

Ethicon Endo-Surgery Partners With Colorectal Surgeons And Community At ASCRS To Improve Patient Outcomes

[...] (EES) will feature its comprehensive portfolio of colorectal solutions and physician-led educational programs, aimed to advance surgical skills in both open and minimally invasive colorectal procedures to promote better patient outcomes, during [...]

New 200 mg Vial for Eloxatin(R) (Oxaliplatin Injection) Offers Greater Convenience and Efficiency of Preparation

[...] ts chemotherapy treatment Eloxatin(R) (oxaliplatin injection) for patients who have adjuvant stage III colon cancer and advanced colorectal cancer, which is expected to offer more convenience, efficiency and safety in the preparation of the inj [...]

Dramatic Increase In Metastatic Colon Cancer Survival

[...] Novel chemotherapy and biological agents for metastatic colorectal cancer, combined with surgical advances in liver resection, have resulted in a dramatic increase in survival for patients with advanced disease, according [...]

Pitt researchers raise concern over frequency of surveillance colonoscopy

[...] nomas, found on a previous colonoscopy. The aim of surveillance is to identify and remove recurrent growths before they advance to cancer. "Guidelines recommend that patients who have had pre-cancerous lesions, especially advanced precancerous [...]

Avastin May Help Colorectal Cancer Patients Live Longer, Study Shows

[...] ZURICH, Jan 26 (Reuters) - Patients with advanced colorectal cancer who received Roche's Avastin live longer when they also receive the drug as part of their second [...]

NDP leader advocates for more cancer screening in Chilliwack

[...] st appeared in Cindy Stewart, it was believed to be too late. In 1996, at just 32 years old, Stewart was diagnosed with advanced colorectal cancer with a large tumour on her colon and another that had spread to her right ovary; she was the youn [...]

Managing Adjuvant Treatment in Colorectal Cancer

[...] Moderator, John L. Marshall, MD, introduces the panel for a unique discussion on advances and challenges in the management of colorectal cancer (CRC). Overall, the discussion will describe new therapies, t [...]

Managing Adjuvant Treatment in Colorectal Cancer

[...] Moderator, John L. Marshall, MD, introduces the panel for a unique discussion on advances and challenges in the management of colorectal cancer (CRC). Overall, the discussion will describe new therapies, t [...]

Cutting-edge technologies signify a new era for colorectal cancer screening

[...] er, M.D., of the University of Texas MD Anderson Cancer Center. "The findings presented today could lead to significant advancements and an overall improvement in the diagnostic efficacy of colon screening." Onco-LIFE Fluorescence Imaging Durin [...]

Largest Ever Data Set Shows Consistent Benefits With Avastin When Used in Combination With Different Chemotherapy Treatm

[...] New data from 4,000 patients show that Avastin (bevacizumab rhuMAb-VEGF) enables patients with advanced colorectal cancer (CRC) to live longer without progression of their disease.(1) The results also confirm that Avast [...]

Additional benefit for patients resulting from combination therapies with Roche cancer medicines

[...] Oral Xeloda combination therapy showed to be as effective as and more convenient than the current standard treatment of advanced colorectal cancer – a further proof of Xeloda's significance in various treatment regimens. * New data underl [...]

Importance Of Colorectal Cancer Screening Highlighted During Annual Scientific Meeting

[...] a higher incidence of colorectal cancer compared to Caucasians. The studies have found that more African-Americans had advanced polyps on the right side of the colon than Caucasians, while results from colonoscopy screenings of Latin Americans [...]

ANAVEX 7-1037 demonstrates chemotherapeutic potential without toxic side effects for the treatment of colorectal cancer, other types of solid tumors

[...] Sciences Corp. ("ANAVEX") today announced that ANAVEX 7-1037 has been shown to kill human HCT116 colon cancer cells in advanced pre-clinical studies. In addition, ANAVEX 7-1037 demonstrated its ability to significantly suppress tumor growth in [...]

Three New Cancer Drugs Now Available In Ontario

[...] the cells in the body. Clinical trials have shown that Avastin is most effective when used as the initial treatment for advanced colorectal cancer. The average length of survival for patients who receive Avastin in combination with other chemot [...]

Merck Serono to Present New Data at ECCO/ESMO Oncology Congress Showcasing Leadership in Personalized Cancer Care

[...] a Spanish Phase II study of Erbitux in combination with capecitabine in the 1st-line treatment of elderly patients with advanced CRC will be also be presented.3 Non-small cell lung cancer (NSCLC) * A meta-analysis of four key studies of Erbitux [...]

Colorectal Cancer: Clinical Research Study Evaluating Targeted Therapy With Patients Whose Cancer Has Spread

[...] up to 25 percent of all patients are diagnosed after their cancer has metastasized (spread to distant organs). In these advanced cases, the goal is to prevent the cancer from spreading further. Doctors around the country are recruiting patients [...]

First Population-wide Evidence: Colonoscopy Protects From Cancer - Even sigmoidoscopy may be very beneficial

[...] Persons who have had a colonoscopy in the past ten years are much less likely to be diagnosed with advanced precancerous stages of bowel cancer. Particularly on the left side of the colon, the risk for cancer and precancero [...]

First Population-wide Evidence: Colonoscopy Protects From Cancer - Even sigmoidoscopy may be very beneficial

[...] Persons who have had a colonoscopy in the past ten years are much less likely to be diagnosed with advanced precancerous stages of bowel cancer. Particularly on the left side of the colon, the risk for cancer and precancero [...]

Should Gene Mutation Alter Colon-Cancer Treatment Options?

[...] offers findings in its January 2011 issue regarding how testing for gene mutation may influence treatment decisions for advanced colon cancer. Up to 80 percent of colorectal cancer patients (CRC) are diagnosed with advanced disease. Often, mono [...]

Treatment For Colorectal Cancer From Sloan-Kettering

[...] oscopic Surgery for Colorectal Cancer Our surgeons currently perform many colorectal operations laparoscopically. Using advanced technology and fiber optics, they can do complex procedures through small incisions. Compared to conventional open [...]

Second Sigmoid Study Ups Early Cancer Detection

[...] hy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner Repeat flexible sigmoidoscopy increased detection of colorectal cancer or advanced adenoma by one-fourth in women and one-third in men, according to the latest results from the Prostate, Lung, Color [...]

As colorectal cancer gets more aggressive, treatment with grape seed extract is even more effective

[...] oing: A University of Colorado Cancer Center study recently published in the journal Cancer Letters shows that the more advanced are colorectal cancer cells, the more GSE inhibits their growth and survival. On the other end of the disease spect [...]

Looking for lessons in cancer’s ’miracle’ responders

[...] . Solit, an oncologist at Memorial Sloan-Kettering Cancer Center in New York City, delved into the case of a woman with advanced bladder cancer who volunteered for a 45-patient study of the Novartis drug Afinitor. He discovered that a combinati [...]

B.C. Gov’t to Invest 35 Million in New Medical Technology

[...] ting edge medical treatment, announced Premier Gordon Campbell and Health Services Minister Colin Hansen. "Investing in advanced medical technology is one of the best ways we can ensure British Columbians have access to the most effective treat [...]

Colorectal Cancer - Avastin arrives in Saskatchewan - Remaining Provinces and Territories must Follow Suit

[...] on his promise for Saskatchewan to provide funding to their Cancer Agency for Avastin in the treatment of patients with advanced colorectal cancer. The premier promised to put patients first and strengthen cancer care for Saskatchewan people. S [...]

Cancer drug has ’huge’ potential

[...] to A diagnosis of Stage 4 colorectal cancer isn’t necessarily a death sentence. At Stage 4, the cancer is in its most advanced stage. It’s inoperable, and it has likely spread to other parts of the body. “But there’s always hope,” sai [...]

Arenegyr: Key Preliminary Results of Phase II Trials in Mesothelioma and Colorectal Cancer Presented at ASCO

[...] other diseases conditions, early diagnosis is often difficult and patients may not be diagnosed until the disease is at advanced stage. Treatment of malignant mesothelioma using conventional 2 Press release therapies has not proven to be succes [...]

Drug prolongs life expectancy for lung cancer patients: study

[...] CHICAGO (AFP) — The cancer drug Erbitux prolonged the lives of patients with advanced lung cancer by five weeks, according to a new clinical study described as an important gain for such individuals. " [...]

Avastin(R) Shows Unprecedented Benefits in Colorectal Cancer Patients, Irrespective of K-Ras Gene Mutation

[...] addition of Avastin to chemotherapy gave the most significant improvement in survival time ever observed in a trial of advanced colorectal cancer, significantly extending the duration of patient's life by 30%. The results of AVF2107 formed the [...]

The Other Women’s Cancer

[...] considered localized early-stage tumors that do not have lymph node involvement. Stage III colorectal cancer is locally advanced and has involvement of regional lymph nodes. Stage IV colorectal cancer indicates disease that has metastasized, or [...]

Exiqon Dx Announces BRAF Mutation Analysis for Predicting Therapeutic Response in Colorectal Cancer Patients

[...] s through its CLIA laboratory in California. Cancer treating physicians now have access to this critical test for their advanced stage colorectal cancer patients who are candidates for anti-EGFR targeted therapy. A recent clinical study correla [...]

Colon Cancer Vaccine

[...] e U.S. this year. Researchers are testing a vaccine that may help reduce the risk of developing cancer in patients with advanced, high-risk colon polyps. Colorectal Cancer Colorectal cancer is the third most common cancer in American men and wo [...]

CBC Radio (Charlottetown) - CCAC IS HOLDING A BREAKFAST FOR MLAS

[...] hose people who already have the disease and in particular those who are the most vulnerable, those who are in the most advanced stages and who really, really require the standard of care in the treatment of the disease that is available in the [...]

News and insights in gastroenterology presented at the ACG’s 75th Annual Meeting

[...] y B. Gonzalez Convention Center in San Antonio, Texas starting Monday October 18, 2010, to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management. Innovative technolo [...]

Jekyll-Hyde microRNA binding variant linked to improved outcome in early-stage colorectal cancer

[...] PHILADELPHIA — A variant site linked to poor outcome in advanced colorectal cancer has now been found to predict improved prognosis in early stages of cancer, according to research [...]

Jekyll-Hyde microRNA binding variant linked to improved outcome in early-stage colorectal cancer

[...] PHILADELPHIA — A variant site linked to poor outcome in advanced colorectal cancer has now been found to predict improved prognosis in early stages of cancer, according to research [...]

Colorectal cancer up in patients younger than 50

[...] By Tom Corwin Staff Writer Monday, March 7, 2011 When he was diagnosed with advanced colon and rectal cancer at the relatively young age of 38, Billy Burkart already had an inspiration for his fight & [...]

Colonic Stenting No Better Than Emergency Surgery

[...] Last Updated: March 14, 2011 Colonic stenting does not offer a decisive advantage over emergency surgery in patients with acute obstructive left-sided colorectal cancer, and may pose safety concer [...]

AACR: Immune Therapy Slows Colon Cancer

[...] of Pennsylvania School of Medicine and Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner ORLANDO — Patients with advanced colorectal cancer had more than a twofold improvement in progression-free survival when immunotherapy was added to [...]

Colorectal Cancer on the Rise in Adults Under 50

[...] II or IV, with stage IV being the most severe grade of the disease. Other factors that increased the risk for having an advanced cancer at diagnosis were being African-American or lacking health insurance. “It's cause for concern,” says Sie [...]

Colorectal Cancer: Preparation, Prevention Can Give You Peace of Mind

[...] By Ranganath Pathak, M.D. Cancer can be a scary word to hear, but with the advances in medicine and a focus on prevention, there is more hope than ever for patients. Colorectal cancer in particular i [...]

There’s an App for Colon Cancer

[...] a cancer diagnosis is not knowing what to do next. You don't even know what you don't know. A new online program offers advanced cancer patients and their doctors the latest disease information they can share and use for customized treatment pl [...]

Bayer Wins Early U.S. Approval for Colon Cancer Drug

[...] (Reuters) --- The U.S. Food and Drug Administration on Thursday approved a new drug for advanced colon cancer developed by Bayer AG, a month ahead of the agency's expected action date for a decision. The drug, to [...]

Colon cancer screening tied to better outcomes

[...] Health) - People who are diagnosed with colon cancer after routine colonoscopies tend to have better outcomes and less advanced cancers than people diagnosed based on symptoms, says a new study. Those who were diagnosed with colon cancer as a [...]

Racial Paradox in Colorectal Cancer

[...] Advanced colorectal neoplasia more common in white men than in black men Black men are at higher risk of developing and dyin [...]

Understanding Clinical Trials

[...] ubstance not expected to have any real therapeutic effect) or a different treatment.  Clinical trials have led to many advances in colorectal cancer prevention, diagnosis, and treatment.  A clinical trial is performed only when there is good [...]

Erbitux Lifts Hopes of Colon Cancer Patients

[...] NEW YORK (Reuters) - Advocacy groups on Friday said patients with advanced colon cancer are hoping ImClone Systems Inc's new drug, Erbitux, will improve their lives and help some survive unt [...]

New cancer drug Avastin keeps cancer under control

[...] stin keeps cancer under control for a significantly longer duration, even when used in a group of elderly patients with advanced colorectal cancer who are too sick to tolerate traditional aggressive chemotherapy. Avastin (bevacizumab, rhuMAb-VE [...]

Three Studies Presented at Plenary Session I Report Inconsistent Results with Antiangiogenic Combinations

[...] receptor, and c-KIT. Two speakers reported that bevacizumab in combination with chemotherapy had a significant survival advantage for patients with metastatic colorectal cancer (mCRC) and advanced non-small cell lung cancer (NSCLC). However, re [...]

Breakthrough Liver Cancer Treatment Found

[...] nroads against liver cancer, one of the more voracious forms of the disease. Nexavar, made by Bayer, gave patients with advanced liver cancer 44 percent more time to live, compared to patients who did not receive the drug, according to results [...]

Drug may help in colorectal cancer when chemotherapy fails

[...] awa Citizen Published:Â Thursday, November 15, 2007 OTTAWA — A Canadian-led international study of patients with advanced colorectal cancer has added "one more tool" for them: a drug that extends their lives by an average of six weeks, a [...]

New article

[...] current colorectal cancer. Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Advanced colorectal cancer refers to cancer that has spread from its site of origin, beyond the colon and nearby lymph nodes [...]

Drug Helps Fight Late-Stage Colon Cancer in Some Patients

[...] — A highly targeted biologic drug called cetuximab (Erbitux) is the first to extend the survival of patients with advanced colon cancer who have otherwise proved resistant to conventional chemotherapy, Canadian researchers confirmed. But [...]

Drug Helps Fight Late-Stage Colon Cancer in Some Patients

[...] — A highly targeted biologic drug called cetuximab (Erbitux) is the first to extend the survival of patients with advanced colon cancer who have otherwise proved resistant to conventional chemotherapy, Canadian researchers confirmed. But [...]

Drug Helps Fight Late-Stage Colon Cancer in Some Patients

[...] — A highly targeted biologic drug called cetuximab (Erbitux) is the first to extend the survival of patients with advanced colon cancer who have otherwise proved resistant to conventional chemotherapy, Canadian researchers confirmed. But [...]

Rural Patients’ Colon And Lung Cancers Diagnosed Earlier, Research Says

[...] s are often assumed to be the top truants in American medicine, not seeking medical attention until a condition is more advanced and less treatable. However, a new study by Dartmouth researchers suggests that urban, not rural, patients are most [...]

New Studies Show That Computer Aided Detection (Cad) Systems Are An Effective Aid In The Detection Of Various Stages And Types Of Colon Cancer

[...] a higher incidence than women.6 Among individuals diagnosed with colorectal cancer, survival is highly dependent on how advanced the disease is at diagnosis. Five-year survival is 90% if the disease is diagnosed while it affects only the large [...]

Colon And Lung Cancers Diagnosed Earlier In Rural Patients

[...] s are often assumed to be the top truants in American medicine, not seeking medical attention until a condition is more advanced and less treatable. However, a new study by Dartmouth researchers suggests that urban, not rural, patients are most [...]

INEQUALITY IN COLORECTAL CANCER CARE REVEALED BY ONTARIO’S NEW CANCER PLAN

[...] cancer; however real concerns remain regarding access to treatments for the disease. Currently, patients diagnosed with advanced colorectal cancer are being denied public access to the standard of care unless they are covered by private insuran [...]

Progress in Personalized Therapy: KRAS Status Predicts Response to First-line Cetuximab for Metastatic Colorectal Cancer

[...] Advancing the use of targeted agents for treating cancer has been linked with determining molecular markers that may predict [...]

Meta-analysis Confirms that Aspirin Helps Prevent Colorectal Adenomas

[...] nal group of researchers have reported that daily use of aspirin may reduce the risk of colorectal adenomas, especially advanced lesions. The details of this study appeared in the February 2009 issue of the Journal of the National Cancer Instit [...]

UPDATE 1-Pfizer’s Sutent fails in colon cancer, trial halted

[...] NEW YORK, June 30 (Reuters) - Pfizer Inc (PFE.N) said a late stage trial testing its cancer drug Sutent in advanced colon cancer was discontinued after it was deemed to be no more effective than standard chemotherapy. An independen [...]

Study Sheds Light on Reason for Sharp Increase in Colon Cancer Survival Rates

[...] The availability of novel treatment options combined with surgical advances has significantly increased survival rates in metastatic colorectal cancer patients, say researchers at The Univers [...]

Colorectal cancer today and tomorrow

[...] ible reasons behind this country’s negative CRC record; gender-specific differences in diagnosis and therapy, and the advantages of current treatments as well as potential advances Prof Petrasch: ‘We have the most aggressive strategy for pr [...]

Colorectal cancer screening could cut future chemotherapy costs in half

[...] Investing in advanced colorectal cancer screening programs — with the exception of colonoscopy — may more than double the savings ass [...]

Medical News: Colonoscopy Benefits Real, but Limited to Left Side - in Hematology/Oncology, Colon Cancer from MedPage Today

[...] r University of Pennsylvania School of Medicine and Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner The incidence of advanced colorectal neoplasms was significantly lower among patients who'd had a colonoscopy in the past than in those who h [...]

New study links smoking to colorectal cancer

[...] as (precancerous polyps) in the colon and may explain the earlier onset of colorectal cancer in smokers, as well as the advanced stage with which they present when compared to nonsmokers. Flat adenomas are more difficult to detect and have more [...]

Nektar ovarian cancer drug benefits women in study

[...] (Reuters) - About 48 percent of women with advanced ovarian cancer saw sustained benefits from treatment with Nektar Therapeutics' experimental drug NKTR-102 in a mid- [...]

Betrayal of the cancer patients: Rationing watchdog accused of talking down wonder drug’s power to save lives

[...] chdog said the drug only prolongs life by an average six weeks - but cancer specialists reject this claim They say some advanced stage bowel cancer patients with very short life expectancy have lived for four years after being prescribed Avasti [...]

Health Care Gap May Raise Rates of Colorectal Cancer Death in Blacks

[...] same age. By the 2000s, that gap had increased to 2.7 years. "Colorectal cancer is one of the few cancers that has had advances in detection, treatment and survival over the second half of the 20th century. But despite these advancements, we o [...]

New target, drug potential found for colon cancer

[...] land LONDON | Mon Jan 31, 2011 4:03pm EST (Reuters) - British scientists said they have found a new target for treating advanced bowel cancer which could also be used to identify tumors that will respond to Bristol Myers Squibb's cancer drug Sp [...]

ASCO: OK to Stay with Avastin in Colon Cancer Tx

[...] Francisco. Continuous use of the monoclonal antibody improved the odds of overall survival 19%, for a median 1.4 month advantage over a strategy of chemotherapy alone after progression (P=0.0062), Dirk Arnold, MD, of the University Cancer Cent [...]

Colorectal Cancer on the Rise Among Younger Adults

[...] ng incidence in older patients. The increasing incidence was found especially in cases involving rectal cancer and more advanced stages of colorectal cancer, as well as in patients of nonwhite race/ethnicity and those lacking health insurance o [...]

Study finds why Roche’s Avastin only works in some patients

[...] By Kate Kelland (Reuters) - Genetic testing could help doctors find the small number of patients with advanced bowel cancer likely to benefit from cancer drug Avastin, scientists said on Tuesday. In a study of Roche's blockbus [...]

High Blood Vessel Density in the Mouth Associated With FAP

[...] Research May Help Advance Screening for Hereditary Colon Cancers by Christina Frangou Abnormally dense blood vessel growth in the skin lining [...]

New App Available in the Fight Against Colon Cancer

[...] 4, 2012 /PRNewswire-USNewswire/ No one wants to hear the words, "you have colon cancer." For patients diagnosed with an advanced form of the disease, these words can be particularly devastating. The five-year survival rate can be a little as 6 [...]

Minimally Invasive Surgery (MIS) Conference

[...] To advance education and awareness of Minimally Invasive Surgery (MIS) within the Canadian surgical community and the public, t [...]

Contrary to popular belief, beta-blockers don’t prevent colorectal cancer

[...] s reported Monday. In fact, long-term use of the drugs might even be associated with an increased risk of developing an advanced form of the disease, they said. Beta-blockers are a family of drugs that reduce blood pressure and improve heart fu [...]

HAI in the Management of Unresectable Colorectal Liver Metastases Meeting - September 7th, 2012, Toronto

[...] HAI in the Management of Unresectable Colorectal Liver Metastases Meeting - September 7th, 2012, Toronto To advance education and awareness of Hepatic Arterial Infusion (HAI) as a therapeutic option in the treatment of unresectable [...]

New Blood-Based Screening Test for Colorectal Cancer

[...] detection most often leads to a complete recovery. An estimated 23,000 Canadians will be diagnosed this year, many with advanced disease. Because most people do not experience any symptoms in the early stages, appropriate screening is critical. [...]

Soy-based compound may reduce tumor cell proliferation in colorectal cancer

[...] Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting. The meeting took [...]

New Colonoscope Provides Ground-Breaking View Of Colon

[...] By Digestive Disease Week ORLANDO, Fla., May 21, 2013 — /PRNewswire-USNewswire/ — A ground-breaking advance in colonoscopy technology signals the future of colorectal care, according to research presented today at Digestive [...]

Managing Adjuvant Treatment in Colorectal Cancer Part 1 & 2

[...] g Adjuvant Treatment in Colorectal Cancer, Part I John L. Marshall, MD, introduces the panel for a unique discussion on advances and challenges in the management of colorectal cancer (CRC). Overall, the discussion will describe new therapies, t [...]

ASCO Highlights Put Variety in Spotlight

[...] ith and without lapatinib. Abstracts 500 and 501. Everolimus plus trastuzumab and vinorelbine in trastuzumab-resistant, advanced breast cancer; results of the phase III BOLERO-3 trial. Abstract 505. Bevacizumab plus standard chemotherapy in rec [...]

Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases

[...] ho undergo emergency compared with elective surgery, both for their initial hospital stay and their long-term survival. Advanced tumor pathology and tumors with unfavorable histologic features may provide the basis for the difference in outcome [...]

Toward the Future of Cancer Prevention

[...] Can most types of cancers be prevented? It's a question that has emerged in the past 20 years, given advances in screening and early diagnosis, rapid developments in genetics and molecular biology, and progress in the treatme [...]

ChondroGene Reports on Blood-Based Colon Cancer Test Development

[...] of 79 percent. The company has also selected a biomarker set of seven genes in another study to identify patients with advanced adenomas and high risk polyps, the type of colon polyps at high risk for developing into colon cancer. The sensitiv [...]

Easier Colon Cancer Test

[...] hat was growing fast. "It wasn't an easy road for me, but lucky enough, I'm here," she says. Now, Echternkamp hopes new advances can help others beat the odds, too. She says, "If there's any testing that can help patients get in and be checked [...]

Scientists turn immune cells into tumour fighters to treat melanoma.

[...] ngineered immune cells in the blood, transforming them into tumour fighters that eliminated melanoma in two men with an advanced stage of the often deadly disease. While 15 other patients with melanoma were not helped by the modified T-cell tre [...]

Chemotherapy and surgery may help colon cancer

[...] ease in check. The study is the first to scientifically test an approach that many doctors have tried for patients with advanced colon and rectal cancers. "It justifies what some of us have already been doing" and shows that aggressiv [...]

Revolutionary drugs fight cancer

[...] che and in the United States by Genentech. It has already proven effective at prolonging life in tests on patients with advanced colon and lung cancer. A study published here this weekend showed that it also doubled the lifespan of those with s [...]

Colorectal Cancer Patients Treated With XELOX Spend Over 160 Fewer Hours Receiving Intravenous Treatment

[...] g and waiting time. Analysis of data from a large Phase III international trial clearly demonstrate the quality of life advantages of using XELOX rather than traditional i.v. regimens consisting of i.v. 5-FU and i.v. oxaliplatin (FOLFOX-4), whi [...]

Survival rates for metastatic colon cancer much improved

[...] sidered a disease with a poor prognosis. But an analysis of survival statistics show that the outlook for patients with advanced colon cancer has greatly improved. Only 8% of patients survived five years with the disease in 1990 compared with 3 [...]

Nova Scotians to petition government to stop denying colorectal cancer patients the life sustaining medication Avastin

[...] est that the government do the right thing and make this drug available to Nova Scotian colorectal cancer patients with advanced disease. Madeline Bolivar, age 72, has spent the summer walking the Bridgewater and other Lunenburg County communit [...]

Bridgewater mom petitions province to cover cost of cancer drug Avastin

[...] res on a petition urging the provincial government to pay for a pricey drug that could help her son and others battling advanced colorectal cancer. At Province House on Thursday, Madeline Bolivar presented NDP Leader Darrell Dexter with a 3,679 [...]

Province adds drug to cancer arsenal

[...] ry 31, 2008 REGINA — Premier Brad Wall confirmed Wednesday Saskatchewan will fund a drug used in the treatment of advanced colorectal cancer, prompting applause at a news conference from a handful of cancer patients and their family membe [...]

Sudburians to access colon cancer screening

[...] ning program for the second deadliest form of cancer could save dozens of Sudbury lives every year - if Sudburians take advantage of it. Health Minister George Smitherman launched a public awareness campaign Friday, called ColonCancerCheck, to [...]

New article

[...] etween life and death. Gourd, a former deputy minister of communications for the federal government, was diagnosed with advanced colorectal cancer in March 2003. It had spread to his liver and lungs, and the resident of Gatineau was told he had [...]

Cancer patients ask Alberta to review stance on costly drug

[...] s for as long as two years by restricting blood flow to tumours, according to the national group. But the treatment for advanced colorectal cancer costs thousands of dollars a month, which Alberta's drug plan does not cover. 'I don't think I wo [...]

Colon Cancer Screening Sooner? Prevalence Of Pre-cancerous Masses In Colon Same In Patients In Their 40s And 50s

[...] enomas was relatively similar in the two age groups, there was a doubling in the prevalence of abnormal cell growth, or advanced neoplasia, in the 50 to 59 age group versus the 40 to 49 age group. While not statistically significant, in the 40 [...]

Amgen Reports Positive Data at ASCO from Three Studies of Denosumab in Cancer Patients

[...] adiation or surgery to bone, and spinal cord compression. The adverse event profile of denosumab was similar to that of advanced cancer patients receiving treatment, and balanced across treatment arms. The most common adverse events included bo [...]

Different type of colon cancer vaccine reduces disease spread, Jefferson scientists show

[...] (PHILADELPHIA) Taking advantage of the fact that the intestines have a separate immune system from the rest of the body, scientists at the Kimmel [...]

Prevalence Of Pre-cancerous Masses In The Colon Same In Patients In Their 40s And 50s

[...] enomas was relatively similar in the two age groups, there was a doubling in the prevalence of abnormal cell growth, or advanced neoplasia, in the 50 to 59 age group versus the 40 to 49 age group. While not statistically significant, in the 40 [...]

Quality of colon cancer surgery determines patient survival

[...] ia plane (1447mm2). Survival results showed that patients undergoing mesocolic plane surgery had a 15% overall survival advantage at five years when compared with those who had surgery in the muscularis propria plane (hazard ratio 0.57 [95% con [...]

Aspirin reduces risk of colon polyps recurring

[...] e detected in 37 percent of 1156 participants given placebo and in 33 percent of the 1542 assigned to aspirin. Rates of advanced growths were 12 percent and 9 percent in the two groups. While the differences might not seem large, aspirin was as [...]

Colorectal Cancer

[...] ecome motivated to undergo screening. Several options are available for CRC screening, each with a different profile of advantages and limitations. Conventional screening methods include fecal occult blood testing (FOBT), flexible sigmoidoscopy [...]

Cancer death rates fall among African Americans - survival rates still low

[...] While death rates from cancer continue to drop among African Americans, the group continues to be diagnosed at more advanced stages and have lower survival rates at each stage of diagnosis compared to whites for most cancer sites. The findi [...]

Vaccine To Prevent Colon Cancer Being Tested In Patients

[...] irected against an abnormal variant of a self-made cell protein called MUC1, which is altered and produced in excess in advanced adenomas and cancer. Vaccines currently in use to prevent cancer work via a different mechanism, specifically by bl [...]

Meaningful progress in therapy options

[...] several new treatment options. These new options are resulting in better survival not yet reflected in NCI statistics. ADVANCES IN CRC THERAPY Until the mid-1990s, mean survival for patients with metastatic CRC was less than 12 months, and 5-f [...]

Leading cancer organizations team up on tumor-promoting protein

[...] Orlando. COX-2 is best known as a target for preventing dangerous polyps that lead to colorectal cancer, but it is also advancing as a target for treatment of many solid tumors. "Our symposium is timely because we are starting to see data from [...]

Targetting guts

[...] he latest advances in metastatic colorectal cancer treatment heralds the future of cancer therapies: patient-specific regimes. ONCOLOG [...]

Genomic Health to Launch Oncotype DX Colon Cancer Test in Early 2010

[...] e selected from more than 4,000 accepted abstracts to be featured in the American Society of Clinical Oncology's (ASCO) advance presscast earlier, address a large unmet need in the treatment of colon cancer by validating a clinical tool that ca [...]

Adjuvant FOLFOX4 increased survival in stage II/III colon cancer

[...] Despite the benefit of adding irinotecan to infusional FU/leucovorin in first-line treatment of patients with advanced colorectal cancer, the topoisomerase 1 inhibitor did not improve survival in the adjuvant treatment of patients wit [...]

Improved Chemotherapy Gives Late-Stage Colorectal Cancer Patients Alternative to Surgery

[...] Most patients with advanced colorectal cancer do not need to undergo colon surgery to treat the disease, researchers reported at the 2009 Ameri [...]

Fecal DNA Methylation Detects Gastric And Colorectal Cancers

[...] ts with colorectal or gastric tumors. Extensive methylation at these gene promoters was much more likely to be found in advanced gastric tumors and colorectal tumors than in normal tissue. Methylation markers were detected in 57% of gastric can [...]

Blackberries help battle cancer and cholesterol

[...] By DR. RICHARD BELIVEAU August is the perfect month to take advantage of freshly-picked blackberries. Less well-known than raspberries, its first cousin, the blackberry is nevertheless [...]

Language a Barrier to Colorectal Cancer Screening in Mexican-Americans

[...] udy from San Diego State University. Nationally, Latinos are more likely to receive a diagnosis of colorectal cancer in advanced stages and have a lower survival rate than non-Latino whites. In the study of nearly 17,000 California residents ag [...]

Amgen to Present Pivotal Data From Four Phase 3 Studies at the ECCO 15

[...] d studies evaluating denosumab versus Zometa(R) (zoledronic acid) for the treatment of bone metastases in patients with advanced breast cancer (the '136' study) and the treatment of bone metastases in advanced cancer patients with solid tumors [...]

New test used at Lincoln center counts cancer cells in blood

[...] It's packing them in on the cancer research circuit. The topic: counting tumor cells circulating in patient blood. For advanced breast, prostate and colon cancers, studies show, when more tumor cells circulate, survival shortens. Reduce the nu [...]

Higher risk of GI diseases may mean more vigilance, earlier screenings for minorities

[...] particular, show the greatest gender disparity versus Hispanic males (47.7 percent vs 28.2 percent). In addition, while advanced stage colorectal cancers showed a steady decline during the study period, African Americans have the greatest propo [...]

Many with cancer gene don’t want to know

[...] his is part of a monthlong series on the battle against cancer in 
Butler County. When Janet Moran was diagnosed with advanced colon cancer at age 23 she knew more than most her age about the disease. Her father had died from it six years ear [...]

African-Americans with colorectal cancer have poorer outcomes, lower survival rates

[...] an College of Surgeons shows that African-American patients with colorectal cancer are more likely to be diagnosed with advanced disease and are less likely to undergo surgical procedures compared with Caucasians, suggesting that improvements i [...]

The Colorectal Cancer Association of Canada applauds Ontario’s decision to expand funding of Avastin

[...] ncer. "The CCAC congratulates the Ontario government for expanding access to Avastin to colorectal cancer patients with advanced disease," said Barry D. Stein, president of the Colorectal Cancer Association of Canada (CCAC). "Ontario patients w [...]

Canadian, US Nurses Discuss State of Cancer Survivorship

[...] MONTREAL—Nurses can play critical roles in making sure the advances in cancer survivorship care are maintained and even expanded in the face of a rapidly increasing survivor populatio [...]

Dr. Kevin N. Sill: The Delivery of Innovation | R&D Mag

[...] Young Innovator of the Year and chief scientific officer of Intezyne Technologies, Inc. (Tampa, Fla.), has designed an advanced method for encapsulating a wide variety of therapeutic agents into a polymer-based drug delivery system, called the [...]

Get your Butt over here! Colorectal Cancer Awareness Month

[...] bitux™ (cetuximab) while patients in Quebec and Manitoba have no access to these medications. Certainly patients with advanced disease have as much right to prolong their lives in Quebec as they do in Ontario. This is simply not acceptable, [...]

Is imaging being overused on Medicare cancer patients? - Diagnostic Imaging

[...] ing diagnostic treatment patterns, and changes in Medicare reimbursement as likely contributors to an increasing use of advanced imaging in cancer patients. The Duke study, which will be published in the April 28 issue of JAMA, showed a steady [...]

Sizzle your meat safely

[...] By DR. RICHARD BELIVEAU, QMI Agency One of the greatest pleasures of summer is being able to finally take advantage of the nice weather and get outside for a barbecue. That being said, it’s important to remember that cooking mea [...]

Pfizer Fights Back Against Forbes

[...] n’t an all-or-nothing process. Significant improvement in outcomes may occur only as the result of accumulated modest advances. No single drug developed in the past decade for advanced colorectal cancer represented a major breakthrough. Rathe [...]

Study calls for colon cancer patients

[...] he use of rosuvastatin (Crestor) to a placebo. The study is being conducted at the Advocate Lutheran General Center for Advanced Care, 1700 Luther Lane, on the campus of Advocate Lutheran General Hospital, in Park Ridge. The goal of the study i [...]

Colorectal cancer: younger and younger patients

[...] 4 years. What is even more alarming is that the cancer detected in these individuals, a majority of them men, is in the advanced stages. Dr David Charles Bartolo is a consultant colorectal surgeon and honorary senior lecturer from the Universit [...]

Racial Disparities in Diagnosis, Treatment and Outcomes of Colorectal Cancer Could Impact Medical Guidelines for Screening and Treatment of Colorectal Cancer

[...] lence of proximal or right‐sided polyps and cancer in this population. Hispanics are more likely to be diagnosed with advanced stage colorectal cancer than non-Hispanic whites and have a lower probability of survival after diagnosis after acc [...]

Men with prostate cancer at higher colon cancer risk: study

[...] 0 men that patients diagnosed with prostate cancer had significantly more abnormal colon polyps, known as adenomas, and advanced adenomas than men without prostate cancer. Most colon cancers begin as adenomas, the researchers said as they prese [...]

KRAS Mutations Predict Colorectal Cancer Outcomes

[...] ool, Boston and Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner Mutations in a key oncogene can predict outcomes for advanced colorectal cancer patients treated with new biological agents, according to a systematic review of published studie [...]

Wait times frustrate cancer patients in Windsor area

[...] eks, Patricia Grubb sat by the phone, nervously waiting for her cancer treatment to begin. Despite being diagnosed with advanced colon cancer, an entire month passed between the senior's surgery and her first cycle of radiation therapy at the W [...]

New article

[...] designed to boost the body's own immune system, researchers were able to roughly double survival time for patients with advanced, metastatic colorectal cancer compared to patients receiving standard chemotherapy alone. In fact, the trial, resul [...]

Moderate Exercise Can Reduce Colon Polyps by One-Third

[...] ther studies, Dr. Nelson Sanchez of Memorial Sloan-Kettering Cancer Center, New York, said during a press conference in advance of the annual Digestive Disease Week. The findings were presented at the meeting on May 8. Of the 982 middle-aged ad [...]

Ostomy guides

[...] e pouch, which snaps or sticks onto the flange. A one-piece appliance has the flange combined with the pouch. There are advantages and disadvantages to both: Two-Piece Advantages Easier to 'burp', that is, allow gas to escape. This is a useful [...]

FDA grants priority review to Bayer’s regorafenib

[...] od and Drug Administration grants priority reviews to medicines that are considered potentially significant therapeutic advancements over existing therapies. A priority review takes six months rather than the usual 10 to 12-months. Regorafenib [...]

FDA fast tracks pharmaceutical sales of Bayer’s new colon cancer drug

[...] There's encouraging news for patients suffering from advanced colon cancer after the Food and Drug Administration (FDA) approved the pharmaceutical sales of another new treatmen [...]

New noninvasive test for colorectal cancer shows promise

[...] Clinic, Rochester, Minnesota, 3Mayo Clinic, Scottsdale, Arizona. We have demonstrated that colorectal cancer (CRC) and advanced pre-cancers can be detected non-invasively by a manual multi-target stool DNA-based test (sDNA-MT) comprising exfol [...]

Three New Genetic Links to Colorectal Cancer

[...] gators have identified three new genetic "hotspots" linked to colorectal cancer. These variants, reported Dec. 23 in an Advanced Online Publication in Nature Genetics, provide new insight into the biology of colorectal cancer — and could [...]

Three New Genetic Links To Colorectal Cancer

[...] investigators have identified three new genetic "hotspots" linked to colorectal cancer. These variants, reported in an Advanced Online Publication in Nature Genetics, provide new insight into the biology of colorectal cancer - and could repres [...]

CJAD Interview with Lisa Blobstein

[...] Lisa Blobstein was just 36 years old and a new mom when her husband was diagnosed with advanced colon cancer. Her 38 year old husband Steve lost his heroic battle in June 2011. Their son AJ was just 17 months ol [...]

Stivarga: New Treatment Options for Colorectal Cancer Patients

[...] "New therapies offer hope for patients living with advanced sickness and highlight the oncology community's ongoing commitment to patients offering not only to be able to impr [...]

Stike Out Colon Cancer! 2nd Annual Softball Game in Memory of Steve Lisiak

[...] Lisa Blobstein was just 36 years old and a new mom when her husband was diagnosed with advanced colon cancer. Her 38 year old husband Steve lost his heroic battle in June 2011. Their son AJ was just 17 months ol [...]

Scientists put bowel cancer under the microscope

[...] ave a good survival rate - 90 per cent after five years - but this figure drops to 68 per cent for those detected at an advanced stage and just 10 per where it has spread to other parts of the body. In the United Kingdom it is the second most c [...]

Exploring the Neoadjuvant Treatment of Rectal Cancer

[...] is Clinical trials have demonstrated that administering neoadjuvant chemoradiotherapy reduces the rate of recurrence in advanced rectal cancer. In most cases, Johanna Bendell, MD, states, neoadjuvant chemoradiation is still the standard of care [...]

Translating genomics in cancer care

[...] Public Health, Yale University, New Haven, Connecticut. There is increasing enthusiasm for genomics and its promise in advancing personalized medicine. Genomic information has been used to personalize health care for decades, spanning the fiel [...]

Thermodynamic Basis for Engineering High-Affinity, High-Specificity Binding-Induced DNA Clamp Nanoswitches

[...] target molecule. In addition to coupling recognition with a large conformational change, this mechanism offers a second advantage: it improves both affinity and specificity simultaneously. To explore the physics of such switches we have dissect [...]

Systemic effect of catumaxomab in a patient with metastasized colorectal cancer: a case report

[...] f a pulmonary metastasis.Case presentationWe describe the case of a 78year old patient initially diagnosed with locally advanced colon cancer and one synchronous liver metastasis in September 2010 who was treated by hemicolectomy and simultaneo [...]

Dr. John Marshall Provides Colorectal Cancer Updates

[...] , MD, professor, Chief, Division of Hematology/Oncology, Georgetown University Hospital, provides updates on the recent advancements in colorectal cancer being presented at the 2014 Gastrointestinal Symposium in San Francisco. Researchers are c [...]

Dr. John Marshall Provides Colorectal Cancer Updates

[...] , MD, professor, Chief, Division of Hematology/Oncology, Georgetown University Hospital, provides updates on the recent advancements in colorectal cancer being presented at the 2014 Gastrointestinal Symposium in San Francisco. Researchers are c [...]

Sure, We’ll (Eventually) Beat Cancer. But Can We Afford To?

[...] eted, they may be used alongside already expensive targeted drugs. And payers are already struggling to fund impressive advances against Hepatitis C, multiple sclerosis, and rheumatoid arthritis, to name just a few other expensive specialty dru [...]

Cancer Olympian Robin McGee an inspiration

[...] were 10 spots to tear-up or admire her pluck. The Port Williams mother and clinical psychologist was diagnosed with an advanced stage of cancer after four local physicians mishandled her care for two years. Three of the four were subsequently [...]

Colorectal Cancer: Don’t Die of Embarrassment

[...] she was referred to Pasqua Hospital in Regina, she had a tumour in her rectum the size of an orange. The cancer was so advanced that it had extended outside the intestinal wall and spread to surrounding lymphoid tissue. After removing part of [...]

PROTEINS - Future of Cancer Diagnosis, Treatment Lies in Tumor

[...] rs of these cancers also proved to be the switch that could turn the disease off. So now researchers are using the most advanced techniques, such as DNA microarrays and proteomic technology, to find those genes and proteins that are specific to [...]

FDA approves first-of-a-kind cancer fighter

[...] irst drug that promises to attack cancer by choking off its blood supply won federal approval Thursday, a treatment for advanced colon cancer called Avastin. It's not a cure, cautioned the Food and Drug Administration: Avastin can extend patien [...]

News from ASCO 2004Cancer and Leukemia Group B (CALGB) Protocol 9633

[...] ectable lung cancer. For example, the International Adjuvant Lung Trial (IALT) showed a modest but significant survival advantage with cisplatin-based adjuvant chemotherapy in stages IA to III NSCLC. On the other hand, Adjuvant Lung Project Ita [...]

Background Information on Intensity Modulated Radiation Therapy (IMRT)

[...] ts have been limited in the doses of radiation that they can use to effectively destroy cancer. A new and revolutionary advancement in radiation treatment called intensity modulated radiation therapy, or IMRT, improves upon this problem. A grea [...]

Metastatic Colorectal Cancer - Phase 3 Clinical Trial of Panitumumab Therapy for First-Line Treatment

[...] therapy for the first-line treatment of metastatic colorectal cancer. The clinical trial, called the PACCE (Panitumumab Advanced Colorectal Cancer Evaluation) study, is a randomized, multi-center, open-label study, with endpoints of progression [...]

Abgenix and Amgen Announce FDA Grants Panitumumab Fast Track Designation for Metastatic Colorectal Cancer

[...] "We are advancing the development of panitumumab with the hope of offering patients a new treatment option in their fight against me [...]

Crohn’s Disease and Colitis: A Higher Risk for Colorectal Cancer?

[...] cer, in its earliest stages, is considered a curable disease. But, unfortunately, it's often a symptomatic. And when it advances, it is not as treatable. So our goal, in colorectal cancer identification, is to find it in its earliest stages and [...]

Health Canada Approves Groundbreaking Cancer Treatment AVASTIN(TM)

[...] h cancer drug AVASTIN(TM) (bevacizumab, rhuMAb-VEGF) has been approved by Health Canada for the treatment of first-line advanced colorectal cancer. This unique, life-extending medicine has been shown to increase patients' life expectancy by an [...]

Gene variant behind cancer development identified

[...]  gene appears to be frequently acquired  in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage. According to the study, transforming growth factor beta (TGF-beta) is a potent naturally occurring inhibitor of c [...]

Recruitment temporarily suspended in an international phase III trial (AVANT) in post-surgical adjuvant colon cancer

[...] aliplatin/5-fluorouracil/leucovorin). With Avastin, people who had previously failed one chemotherapy regimen for their advanced disease, lived nearly two months longer, on average, compared to those who received chemotherapy alone (12.5 months [...]

Tories Call For Access to Life-Extending Cancer Drug

[...] n Leader Stuart Murray and Health Critic Heather Stefanson pressed the NDP government to provide Manitobans living with advanced stages of colorectal cancer with full funding for the treatment drug Avastin. "Avastin is a drug that could increas [...]

Merck KGaA: Erbitux(R) (cetuximab) Continues to Deliver its Promise

[...] irst-line use of Erbitux with chemotherapy (cisplatin and vinorelbine) versus chemotherapy alone in 1,125 patients with advanced NSCLC. "Data on Erbitux presented at this year's ASCO Annual Meeting reinforce the outstanding efficacy in first an [...]

FDA Approves Avastin(R) in Combination With Chemotherapy for Second-Line Metastatic Colorectal Cancer Patients

[...] The approval is based on results of a randomized, controlled, multicenter Phase III trial (E3200) of 829 patients with advanced or metastatic CRC who had received previous treatment with irinotecan and 5-FU as initial therapy for metastatic di [...]

Patient Advocate and World-Famous Cyclist Lance Armstrong to Receive 2006 Special Recognition Award

[...] team." Armstrong's advocacy efforts stem from his personal experience with cancer. At age 25, he was diagnosed with an advanced form of testicular cancer. As the cancer had already metastasized to his abdomen, lungs, and brain, his chances for [...]

Colorectal cancer - Treat it!

[...] sed screening program for colorectal cancer in Ontario. In the interim, there are thousands of patients in Ontario with advanced colorectal cancer who are being let down and are not receiving the standard of care they are entitled to in accorda [...]

Colorectal Cancer - Nova Scotia, let’s get it right!

[...] ecessary recourses are allocated for these programs. In the interim, there are hundreds of patients in Nova Scotia with advanced colorectal cancer who are being let down and are not receiving the standard of care they should be entitled to in a [...]

Colorectal Cancer - Saskatchewan - Compassion vs. Responsible Government?

[...] m and to ensure the necessary recourses are allocated for these programs. In the interim, patients in Saskatchewan with advanced colorectal cancer are being let down and are not receiving the standard of care they should be entitled to in accor [...]

Cancer Cases Up, but Mortality Rate Drops

[...] JEDDAH, 17 February 2007 — Recent advances in cancer research, diagnosis and treatment will be the focus of a major international symposium that opens at Inte [...]

MultiCell Technologies Announces Prospective Cancer Treatment Drug

[...] BUSINESS WIRE)—Feb 15, 2007 - MultiCell Technologies, Inc. (OTCBB:MCET), developing first-in-class drugs based on advanced immune system modulation technologies, announced today it has reached a developmental milestone to advance its colo [...]

Light Sciences Oncology Receives Special Protocol Assessment for Pivotal Phase III Trial of Litx(TM) Therapy in Metastatic Colorectal Cancer

[...] ments for a Phase III clinical trial. "The SPA for MCRC is a significant step forward in our goal to make even the most advanced cancer a treatable chronic disease," says Llew Keltner, M.D., Ph.D., President and CEO of Light Sciences Oncology. [...]

Colorectal Cancer Association of Canada - Colorectal Cancer Screening - Alberta, it’s a Stampede!

[...] amp; Community Oncology, Alberta Cancer Board, "This will mean fewer Albertans having to fight deadly battles with advanced colorectal cancer - battles too often lost". The Alberta screening program will request residents of the provi [...]

Colorectal Cancer - Nova Scotia

[...] onnors a well known executive and lawyer who is a patient in Dartmouth, Nova Scotia." "As a Nova Scotian with advanced colorectal cancer, I look forward to the province's continuing initiatives to move the program forward, together wi [...]

Cancer report leads to call for screening

[...] women will be diagnosed with breast cancer and 55 with cervical cancer. Ms. Summers said early detection and treatment advances have resulted in a national breast cancer mortality rate that is currently at its lowest level since 1950. But many [...]

Colorectal cancer Prevent it or treat it

[...] able and unethical decisions by limiting access to treatment as they refuse to cover the cost of treating patients with advanced disease with what has become the standard of care elsewhere and in particular in the United States," says Stei [...]

Colorectal Cancer Patients Denied Life-Extending Treatment

[...] ntly considered, and in some cases refused, funding for Avastin (bevacizumab), a targeted therapy and one of the latest advances approved in Canada in the treatment of colorectal cancer. Canadians with colorectal cancer have been waiting patien [...]

Colorectal Cancer Screening to at Least Age 84 Appears Essential for Elderly

[...] atients were younger than 80. Researchers collected data on the number and location of adenomas, histology, presence of advanced adenomas, and colon cancer. In this Buffalo study, colorectal adenomas were detected more frequently in older patie [...]

One cancer, two ways to look

[...] uncomfortable and unpleasant test. Lack of resources and a shortage of family physicians also might be a factor. Recent advances in imaging technology have led to the development of a less invasive screening test for colorectal cancer. CT scan [...]

Navigating our health-care maze

[...] anged over the years - from crisis counsellor to patient advocate. Photograph by: Phil Carpenter, The Gazette "You have advanced colorectal cancer that has spread to your liver and to your lungs," the oncologist said in a clipped tone. "You don [...]

The Case of the Ruthless Ruler With a Deadly Disease

[...] this time, based on ideas traceable to Galen, all cancer is thought to be caused by an excess of black bile. * Initial advances in anatomy and physiology during this century will eventually lead to the development of surgical techniques for co [...]

Bowel Cancer Patients Live Longer Taking Xeloda

[...] 2008, the EU approved Xeloda in combination with any chemotherapy in all lines of treatment with or without Avastin for advanced colorectal cancer. This year will see 281,700 suffer with adjuvant colon cancer in the majority of the developed wo [...]

PROVINCE ANNOUNCES NEW FUNDING FOR CANCER-FIGHTING DRUGS, INCLUDING ONE THAT’S HELPING PORT COLBORNE NATIVE KEVIN BIGFORD IN HIS FIGHT

[...] olborne native who now lives in Kitchener. Bigford was diagnosed with stage 4 colorectal cancer last November, the most advanced form of the disease. In the past, a diagnosis like that would have been a death sentence. But new treatment options [...]

Study: 5-ASA Not Useful in Colon Cancer Prevention

[...] gstanding ulcerative colitis (UC). Those with flat low-grade dysplasia (fLGD) also have a higher rate of progression to advanced neoplasia than those with no dysplasia (NoD) or indefinite dysplasia (IND), the study said. “Some studies have su [...]

CANCER DISPARITIES ARE TARGET OF $15 MILLION GRANT TO UC SAN DIEGO, SAN DIEGO STATE UNIVERSITY

[...] r Center and academic medical center, with SDSU, a university with strong ties to a broad segment of the region, taking advantage of the strengths of both. “Because we have such diversity here in San Diego, the issue of cancer disparity i [...]

Thiopurines Reduce Colorectal Cancer Risk in Patients With Inflammatory Bowel Disease: Presented at ECCO-IBD

[...] with inflammatory bowel disease (IBD) receiving thiopurines have a 3-fold decrease in the risk of developing colorectal advanced neoplasias, researchers reported here at the 4th Congress of the European Crohn's and Colitis Organisation (ECCO-IB [...]

What’s more than six feet tall and full of crap!

[...] s year. Following this campaign, Nova Scotia and Ontario announced funding for Avastin, a life-extending medication for advanced colorectal cancer patients. These provinces now join British Columbia, Quebec, Newfoundland and Saskatchewan in cov [...]

Aspirin & Colorectal Cancer Prevention Fish Oil & Respiratory Infections in Children

[...] e secretly assigned an aspirin pill each day, 33 percent were found to harbor colorectal adenomas while being observed. Advanced precancerous adenomas were also identified in 12 percent of the patients in the placebo group, while 9 percent of t [...]

Cancer patients win drug funding

[...] he decision follows an Alberta Cancer Board recommendation in =anuary that government fund Avastin for the treatment of advanced colon =ancer. Avastin has been at the centre of a national debate about costly =ancer drugs, but the board endorsed [...]

Get Your Butt Over Here!

[...] s year. Following this campaign, Nova Scotia and Ontario announced funding for Avastin, a life-extending medication for advanced colorectal cancer patients. These provinces now join British Columbia, Quebec, Newfoundland and Saskatchewan in cov [...]

Anti Colon Cancer Vaccine Undergoes Testing

[...] l growths in the intestinal lining called polyps, which are called adenomas when they become cancerous. When developing advanced adenomas, people undergo repeated invasive surveillance tests, such as colonoscopy, in order to remove recurrent po [...]

’Personalized Medicine’ Avances Colon Cancer Treatment Dr. Olga Falkowski on Testing for K-RAS Gene Mutation Helping Pinpoint Individual Therapies

[...] ees. "Until recently, treatment for colon cancer patients was determined by results of controlled clinical trials. Now, advances in the identification and understanding of molecular and biochemical events leading to the development of cancer an [...]

Cancer Research and the Stimulus

[...] : "shovel ready," recently peer-reviewed and new, highly meritorious requests for funding capable of making significant advances with a two-year grant; Projects that accelerate the tempo of ongoing science through targeted supplements to curren [...]

New Colon Cancer Vaccine Attacks Emerging Tumors

[...] be particularly useful to treat patients at high-risk for developing colon cancer, as many precancerous polyps, called advanced adenomas, give off abnormal levels of the protein MUC1. About half of all advanced adenomas and the majority of col [...]

The ’Molecular Basis Of Colorectal Cancer’ - New England Journal Of Medicine Publishes CWRU Review

[...] r, drive its progression, and determine its responsiveness or resistance to antitumor agents," wrote Dr. Markowitz. Key advances that the article singled out toward meeting these goals are: * Discoveries in DNA sequencing technology have made i [...]

Gene test can identify bits of cancer in blood

[...] l Institute, who worked on the study published in the journal Science Translational Medicine. The gene-based test takes advantage of rapid advances in the technology to sequence whole genomes — all of a person's genetic code — once a very c [...]

FOBT and FIT

[...] cer when colonoscopy is used as the gold standard for cancer detection. [4],[5],[6],[7]   The sensitivity to detect an advanced adenoma (polyp > 9mm, villous features or high grade dysplasia) is only 18%.  [4], [5],[6],[7]  When the guaia [...]

Cetuximab In Colon Cancer Therapy: New Recommendations

[...] tumors had been surgically removed. Based on earlier studies, cetuximab is now indicated for treatment of patients with advanced colorectal cancer whose tumors do not have a mutation in the KRAS gene. KRAS is one of a series of genes along a pa [...]

Involvement of hyaluronidases in colorectal cancer

[...] s tumor growth, infiltration and angiogenesis, but their exact role in tumor promotion or suppression is not clear yet. Advanced colorectal cancer is associated with elevated amounts of hyaluronan of varying size. The aim of the present study w [...]

Colon Cancer Drug Avastin Failed to Extend Survival – Roche

[...] ” The company said, “it is becoming increasingly clear that the effects of Avastin are different in the metastatic (advanced) and early disease settings” in colon cancer. Roche said it is analyzing the data from this study along with a re [...]

Nutrition and Physical Activity During and After Cancer Treatment: An American Cancer Society Guide for Informed Choices

[...] tivity issues during the phases of cancer treatment and recovery, living after recovery from treatment, and living with advanced cancer; select nutrition and physical activity issues such as body weight, food choices, and food safety; issues re [...]

Too Many Cancers Still Spotted Too Late: CDC

[...] ay News) — Although screening tests are widely available, many cancers aren't diagnosed until the disease is well-advanced and, therefore, less treatable, a new U.S. government report finds. Almost one-half of colorectal cancers and cervi [...]

Survival varies for bowel cancer ops

[...] ary colorectal cancer diagnosed between January 1 1998 and December 31 2006. Data were extracted on their age, sex, how advanced the cancer was, date of diagnosis, date of death (where relevant) and the treatment they received (the type of surg [...]

FDA Approves Fusilev® For Use In Patients With Colorectal Cancer

[...] r the use of FUSILEV® (levoleucovorin) in combination with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer. This new, expanded indication supplements the original 2008 FDA approval of FUSILEV. [...]

Celebrex may curb colon cancer, but with caveats

[...] en followed the people willing to continue the research for another 2 years, noting who developed new polyps, including advanced polyps with features that suggest they're more likely to become cancerous. Approximately half of the people who sta [...]

Urine test could hold key to early cancer diagnosis

[...] test, new research suggests. Edinburgh University scientists have identified key proteins in the urine of patients with advanced cancers. The findings could help the detection of these cancers in people who have not yet started to show symptoms [...]

Survivors of yucky colon cancer give hope to others

[...] es together. And then I met Barry Stein. Fifteen years ago, the Montreal lawyer was diagnosed with colorectal cancer so advanced that it had metastasized in his liver and his lungs. He underwent multiple surgeries in the U.S., including an expe [...]

PET & Colorectal Cancer

[...] it is currently the most effective way to check for cancer recurrences. Studies demonstrate that PET offers significant advantages over other forms of imaging such as CT or MRI scans in diagnosing disease. PET images demonstrate the chemistry o [...]

Cancer screening: It can save your life

[...] al cancer was caught earlier and therefore became less deadly. “Colon cancer is a silent cancer until it’s very far advanced. So (with) colon cancer you’ve got to go and look for it if you want to find it early. With any cancer, the earli [...]

Colon cancer may appear earlier in men

[...] n Austrian researchers analyzed the results of more than 40,000 colonoscopies, they found that men had a higher rate of advanced tumours at ages 40 to 49, a decade earlier than women. The finding "indicates a significantly higher rate of these [...]

Europe Dominates Colorectal Cancer Trial Efforts

[...] treasure,” but some in the field believe that the cooperative groups are beginning to pose an impediment to research advances through their sheer size and bureaucracy. Consent forms are the size of a small city phone book, and folders contai [...]

Research supports success of non-invasive tests in detection of colorectal cancer

[...] reby, for preventing the appearance of the cancer and/or improve the reduction in the number of persons diagnosed at an advanced stage of the illness, with the concomitant improvement in survival rates. However, to date the advantages or otherw [...]

Do UK guidelines catch more colon polyps than U.S.?

[...] , about 4 percent of U.S. low-risk patients and 11 percent of higher-risk patients were diagnosed with pre-cancerous or advanced polyps. According to UK criteria, 4 percent of low-risk, 10 percent of intermediate-risk and 19 percent of high-ris [...]

Can a new vaccine prevent colon cancer?

[...] in the January issue of the journal Cancer Prevention Research. The study involved people with a previous history of an advanced adenoma, which places them at higher risk for subsequent colorectal cancer. “Around 30 to 40 percent of these pat [...]

Low bowel cancer survival in the UK likely to be due to differences in staging and treatment

[...] t in the UK - only 8% compared with 11-17% elsewhere. But UK patients were also less likely to be diagnosed at the most advanced stage (20% at stage D, compared with 24-31% elsewhere). For both colon and rectal cancer, survival among UK patient [...]

Lymph node removal influences outcome in colon cancer

[...] involving over 3,200 patients and showed that those who had more than 20 lymph nodes removed had a 14 per cent survival advantage over those who had fewer than 11 nodes removed – this data referring to stage II disease. In stage III disease, [...]

Viatronix’s V3D-Colon software used in another clinical study relating to colorectal cancer screening

[...] idence and statistical proof that colorectal polyp-volume growth over time delivers true clinical value for identifying advanced adenomas. The advanced adenoma polyp is the primary target in colorectal cancer screening. When an advanced adenoma [...]

Australian Researchers Have Found That Cancer Cells Use Camouflage To Trick Our Bodies

[...] he cancer to spread through the body.” “What this discovery provides us with is a clear path for new treatments for advanced cancers, because we can develop an antibody to block CD96, now that we know it is an immune checkpoint inhibitor. [...]

No need here for the Man from Glad

[...] ble bag, or pouch is attached. Stools are then eliminated into the colostomy bag. Medical experts agree that, given the advances in surgical techniques and knowledge, most patients with colorectal cancer do not end up with the bag. And unless t [...]

Living with Colorectal Cancer

[...] rience to rely on. Have someone come to medical appointments with you to help you make sense of what is happening. Take advantage of friends' offers to help you with the day-to-day activities. Having someone help with your shopping or dropping [...]

CCAC’s Advocacy Goals

[...] posing a special problem that has received high profile media attention. While forming part of the standard therapy for advanced disease in many other countries, provincial governments, worried about their drug budgets, have been debating the c [...]

News from ASCO

[...] al Abstract Presentation, Colorectal Cancer, American oncologists may soon have a new standard front-line treatment for advanced colorectal cancer. During his presentation, Richard M. Goldberg, MD, study chair, included an unexpected update to [...]

From ASCO: Colorectal Cancer information for patients

[...] ancer covering such topics as: - Improvements in colorectal cancer detection and treatment - New chemotherapy drugs for advanced colorectal cancer - Genetic susceptibility and testing - The importance of screening and early detection - Understa [...]

Burns case shows need to screen for colon cancer

[...] tarts this week." He said the treatments will be daily, five days a week, for up to eight weeks. That suggests a fairly advanced cancer. Otherwise, it would have been nipped in the bud, quite literally. Most colorectal cancers occur in the desc [...]

Calcium Reduces Risk for Colorectal Cancer

[...] protects against all types of colorectal polyps, but the antineoplastic effect seems to be greatest for histologically advanced colorectal lesions, those most likely to progress to cancer. In the randomized double-blind, placebo-controlled Cal [...]

News from ASCO 2004Cancer and Leukemia Group B (CALGB) Protocol 9840

[...] CANT IMPROVEMENTS IN EFFICACY WITH WEEKLY CHEMOTHERAPY (PACLITAXEL) COMPARED TO STANDARD 3-WEEKLY THERAPY IN WOMEN WITH ADVANCED BREAST CANCER - Response to weekly paclitaxel is greater than in patients on standard 3-weekly treatment - NEW ORLE [...]

Novartis to Seek OK for Five Drugs in 2005

[...] d also presented new data on four other drug candidates and said only one product that had already reached a relatively advanced stage of development dropped out of the pipeline. The dropout is a compound called TCH346, which Novartis tested fo [...]

Novartis to Seek OK for Five Drugs in 2005

[...] d also presented new data on four other drug candidates and said only one product that had already reached a relatively advanced stage of development dropped out of the pipeline. The dropout is a compound called TCH346, which Novartis tested fo [...]

Novartis to Seek OK for Five Drugs in 2005

[...] d also presented new data on four other drug candidates and said only one product that had already reached a relatively advanced stage of development dropped out of the pipeline. The dropout is a compound called TCH346, which Novartis tested fo [...]

Study: Colorectal cancer screening still lags

[...] cancer are diagnosed in hospital, a new study has found, suggesting many only learn of their illness when it reaches an advanced stage. In a study of Ontario adults conducted between 1993 and 2001, researchers found that the number of newly-dia [...]

Men more likely to get screened for prostate cancer than colon cancer, U-M study finds

[...] ebated. If we can turn the PSA test into an opportunity to encourage men to get their colons checked too, it would take advantage of the public demand for PSA testing," says lead study author Ruth Carlos, M.D., assistant professor of radiology [...]

COMMENTS AND CONTROVERSIES FOLFOX for Stage II Colon Cancer? A Commentary on the Recent FDA Approval of Oxaliplatin for Adjuvant Therapy of Stage III Colon Cancer

[...] OX in the adjuvant setting is a welcome and clinically important addition to improving outcome in patients with locally advanced colon cancer, the restriction of the labeled approval (in the United States and Europe) to stage III disease alone [...]

Kodak to Offer Innovative 3D Software for Review, Management of Virtual Colonoscopy Images

[...] outstanding software for virtual colonoscopy applications that is a perfect fit with our strategy of providing the most advanced 3D imaging applications to our customers," said Michael Jackman, General Manager of Healthcare Information Systems [...]

A Role for Hepatic-Directed Chemotherapy in Colorectal Liver Metastases

[...] r Departments of Internal Medicine and Pharmacology and the Cancer Center, University of Michigan, Ann Arbor, MI Recent advances in the systemic therapy of colorectal cancer seem to have made regional therapy of hepatic metastases passé. Altho [...]

Women’s Preference for Female Colonoscopists Presents a Barrier to Colon Cancer Screening

[...] The female respondents were 40-70 years old, 85% Caucasian, 70% married, 99% high school graduates, 49% held college or advanced degrees, 57% were employed, 21% retired, and over half had a gross annual household income of greater than $60,000. [...]

Chemotherapy, Radiation and Rectal Cancer

[...] Having chemotherapy and radiation therapy before advanced rectal cancer surgery results in an increased likelihood of preserving the anal sphincter, according to a new study [...]

Blood Test Might Spot Colon Cancer

[...] (APC) gene, a warning sign of malignancy. The blood test appears to be 100 percent effective in screening patients with advanced stage colorectal cancer, while researchers were able to identify early-stage disease in more than 60 percent of cas [...]

Pro-Pharmaceuticals Reports Enrollment Progress in Phase II Colorectal Cancer Trial with DAVANAT(R)/5-FU

[...] livers chemotherapy drugs to protein receptors (lectins) that are specific to cancer cells. Pro-Pharmaceuticals, Inc. - Advancing Drugs Through Glycoscience(R) Pro-Pharmaceuticals is a drug development company commercializing a new generation o [...]

Genzyme Launches Colorectal Cancer Test to Determine Appropriate Camptosar(R) Dosage

[...] nd services helping patients in more than 80 countries, Genzyme is a leader in the effort to develop and apply the most advanced technologies in the life sciences. The company's products and services are focused on rare inherited disorders, kid [...]

Bile duct cancer, liver cancer, or metastatic colorectal cancer: focused radiation combined with chemotherapy

[...] al ulcers or bleeding, liver disease from the radiation and problems from the catheter. The chemotherapy delivery takes advantage of the liver having two major blood supplies but needing only one. The tumor lives off one of the two blood suppli [...]

NCCN Updates Colon Cancer Guidelines

[...] al studies and changing practice patterns. One significant change is the recommendation that all first-line therapy for advanced or metastatic disease should include bevacizumab (Avastin) in the treatment regimen. The panel also added a new reg [...]

Meats differ in effect on colon cancer risk

[...] verall, the one-quarter of patients with the highest intake of processed meat were 75 percent more likely to develop an advanced polyp compared with the one-quarter of patients who ate the least processed meat, the researchers found. In contras [...]

EXACT Sciences Announces Results of Research Study Showing Significant Improvement in Colorectal Cancer Screening Technology; New DNA Marker Formulation Demonstrates Sensitivity Above 80%

[...] ting colorectal cancer in a recent research study. The blinded study was designed to test the efficacy of technological advances to enhance colorectal cancer detection in stool. The study results have been submitted for presentation at the upco [...]

What’s New in Hereditary Colorectal Cancer?

[...] ultiple, right-sided, poorly differentiated, mucinous, or DNA diploid,20 while adenomas are more numerous but show less advanced histology.21 Importantly, the risk of both CRC and extracolonic cancers typical of HNPCC is lower in members of AC- [...]

Cancer Screening Rates Remain Unchanged

[...] available to screen early for common cancers when they can be most successfully treated, too many people aren't taking advantage of the examinations, a new report finds. There were some slight increases — and decreases — in the rat [...]

Cancer patients in province wait less time for radiation

[...] blood test, a proven method for detecting cancer, she said. That means colorectal cancers aren't being caught until in advanced stages, when positive outcomes are slim. "As the niece and daughter of two men who died from colorectal cancer [...]

Study Sets Treatment Standard for Elderly with Colon Cancer

[...] patient from receiving FOLFOX therapy. This includes people who had just undergone surgery for colon cancer, those with advanced disease who are receiving their first chemotherapy treatments and patients with advanced disease who are getting a [...]

Health Canada approves Xeloda(R) for adjuvant therapy in the treatment of colon cancer

[...] h XELODA compared to 30 visits if treated with i.v. 5-FU/LV(2). This results in significant cost savings - an important advantage for doctors, nurses and pharmacists in today's healthcare environment. Roche has a large ongoing study program loo [...]

Conflicting Studies Over Colon Cancer Prevention and Diet

[...] as white breads, crackers, muffins, cakes and cookies should be eaten only on occasion. It is an excellent time to take advantage of the great-tasting whole grain products available now, and dress up some fruit for dessert. This not only limits [...]

Cancer Therapy Based On Anatomical Location May Soon Be Obsolete

[...] rticular anatomically defined cancer, we may not initially choose the best therapy for the individual patient. And with advanced cancer, a patient may get only one shot at the right therapy — making the wrong choice could be deadly." Acco [...]

Cancer services for British Columbians looking up thanks to support for national cancer strategy

[...] overnment's support for the Strategy and look forward to working at both a national and provincial/territorial level to advance the goals of the CSCC." "For more than six years, major cancer organizations across the country have shown an unyiel [...]

Pinning hopes on `wonder drug’

[...] s that represent breakthroughs — or are marketed as breakthroughs — in medical treatment with a significant advantage over every other drug out there used to treat the same condition. Right now, he often finds himself smack dab in t [...]

Lifestyles: Matter of life and death

[...] of radiation and chemotherapy five weeks before surgery is less toxic and improves survival," Ally said. "We have more advanced chemotherapy and antibody treatments that have shown some promise. Even in advanced stages, the disease can be mana [...]

Arthritis drug prevents colon cancer

[...] , the research team found that the daily dose of celecoxib (Celebrex®) reduced the recurrence of precancerous and more advanced adenomas (polyps) by 36 percent among the patients studied. "Celecoxib 400 mg once daily significantly reduced colo [...]

Pre-Surgery Chemo Ups Colon Cancer Survival

[...] By Will Boggs, MD NEW YORK AUG 30, 2006 (Reuters Health) - In patients with advanced colorectal cancer that has spread to the liver, the tumors may initially be impossible to remove adequately by surg [...]

About Selective Internal Radiation Therapy (SIRT)

[...] Selective Internal Radiation Therapy (SIRT) is a revolutionary treatment for advanced liver cancer that utilizes new technologies to deliver radiation directly to the site of tumors. Conventional radio [...]

New ’smart’ pill halves cancer treatment time

[...] venience of the new regime will dramatically improve the quality of life for around 13,000 patients each year, who have advanced disease. A new trial shows the benefits for patients taking the oral tablet Xeloda in combination with another chem [...]

New ’smart’ pill halves cancer treatment time

[...] venience of the new regime will dramatically improve the quality of life for around 13,000 patients each year, who have advanced disease. A new trial shows the benefits for patients taking the oral tablet Xeloda in combination with another chem [...]

Roche cancer pill as effective as intravenous drug

[...] s as effective — in terms of progression-free survival — as standard intravenous treatment in patients with advanced colorectal cancer. Results from a Phase III trial presented on Monday at the European Society for Medical Oncology [...]

Updated ASCO Guidelines Highlight CEA Tumor Marker for Colorectal Cancer

[...] thus remains a good candidate for aggressive treatment. "The updated CEA tumor marker recommendations really signal the advances we have made in the treatment of colorectal cancer," Dr. Locker, from Northwestern University Feinberg School of Me [...]

Updated ASCO Guidelines Highlight CEA Tumor Marker for Colorectal Cancer

[...] thus remains a good candidate for aggressive treatment. "The updated CEA tumor marker recommendations really signal the advances we have made in the treatment of colorectal cancer," Dr. Locker, from Northwestern University Feinberg School of Me [...]

Doctors giving cancer patients alternatives to chemo.

[...] by focusing on the epidermal growth factor receptor that drives tumor growth. The hope and promise of cancer-treatment advancements is creating drugs that limit negative effects on patients, Baynes said. One drug, Gleevec, has shown what can b [...]

Colorectal Cancer Screening - Manitoba -Spirited Energy on the Move!

[...] ill not only save lives and permit treatment of patients at an earlier stage than in the past, but also be economically advantageous in view of the high cost of treatment in Canada," noted Stein. "We should not forget about those patients who h [...]

Colon Cancer Survival Linked To Number of Lymph Nodes Examined

[...] han 20 lymph nodes were examined, compared to less than 11 nodes among patients who have Stage II cancers. The survival advantage was even greater - 23 percent - in patients with Stage IIIA and IIIB cancer if more than 40 nodes were evaluated, [...]

Magnetic Resonance (MR) Colonography: Another “Virtual” Tool for the Detection of Colorectal Cancer

[...] not undergo conventional colonoscopy. Its value in screening asymptomatic individuals has not yet been determined. [41] Advantages and Disadvantages Like CT colonography, MR colonography has similar diagnostic accuracy to colonoscopy in detecti [...]

Fighting cancer and geography

[...] ore than anything else. If we compare it to childhood leukemia that’s how we almost moved to virtual cure, little advance and little advance at a time." Ultimately, argues Stein, Ottawa may need to step in to provide provinces with s [...]

Trade gambit doubles cost of cancer medicine

[...] secret information. There's an obligation on us to not disclose it in such a way that it would cause unfair commercial advantage for someone else." The amendments, effective Oct. 5, 2006, essentially permit Canada to conform to the North [...]

Colorectal Cancer Screening - It’s a GO - Ontario!

[...] ill not only save lives and permit treatment of patients at an earlier stage than in the past, but also be economically advantageous in view of the high cost of treatment in Canada," noted Stein. According to Stein, those who question the [...]

Colorectal Cancer - New Year Resolutions and 2006 Reflections

[...] were denied timely access to effective treatment. We are hopeful for all those patients who did benefit from the latest advances in technology, such as PET scans, or effective new therapies such as avastin either privately or with the help of t [...]

Vitamin deters cancer risk

[...] of vitamin D in 279 women with invasive breast cancer. The disease was in its early stages in 204 of the women; and in advanced stages in the remaining 75. Vitamin D levels were significantly higher in the women with early stage disease than i [...]

Studies Demonstrate Increased Efficacy Of Erbitux In Metastatic Colorectal Cancer Patients With KRAS Wild-type Tumors

[...] US, and Venezuela. In addition, Erbitux in combination with radiotherapy has been approved for the treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN) in 61 countries: Argentina, Australia, Belarus, Brazil, Chile, [...]

Colorectal Cancer Awareness Month Celebrates Progress—More Change Critical

[...] ewfoundland now fund Avastin (bevacizumab), an effective medication that has been shown to extend life in patients with advanced colorectal cancer. “Patients who do not live in the above provinces are forced to either pay the high cost of the [...]

High cost of living; Port native denied funding for cancer fighting drug

[...] iver and chemotherapy began in February. He is currently diagnosed with Stage 4 metastatic colorectal cancer - the most advanced stage of the disease. The disease, and what followed, has opened his eyes to the Ontario health-care system. He ass [...]

Discovery Of A Novel Mechanism For The Development Of Colon Cancer

[...] y the age of 50, it is estimated that only a few percent of adenomas will progress to cancer. The study published as an advance online publication of Cancer Cell, describe a mechanism by which harmless colon polyps acquire the ability to form m [...]

Woman can now buy cancer drug at cost

[...] same benefits and that Nova Scotia will eventually pay for the pricey treatment. Marlene George, 47, was diagnosed with advanced colon cancer a year ago and has been taking Avastin and having chemotherapy for 10 months. Her husband Blair George [...]

Woman can now buy cancer drug at cost

[...] same benefits and that Nova Scotia will eventually pay for the pricey treatment. Marlene George, 47, was diagnosed with advanced colon cancer a year ago and has been taking Avastin and having chemotherapy for 10 months. Her husband Blair George [...]

Nova Scotia answers the call of cancer patients for colorectal cancer screening and access to Avastin

[...] re in the treatment of the colorectal cancer by funding Avastin (bevacizumab), and making it available to patients with advanced disease. This is something we have been advocating for and will continue to do so across Canada," said Stein. Nova [...]

Merck KGaA’s Erbitux Drug May Get Edge on Avastin

[...] he disease's progression by 28 days compared to conventional drug therapy. Morgan Stanley analyst Andrew Baum said this advantage may still not be enough for European regulators to make Erbitux a first-choice treatment over Avastin. To find tho [...]

Eloxatin regimen improving colon cancer survival

[...] tion of chemotherapy drugs that includes Eloxatin works better and has fewer side effects than the standard therapy for advanced colorectal cancer. Called Folfox (a drug combination of 5-FU, leucovorin and Eloxatin), this regimen has been found [...]

Discovery Of A Novel Mechanism For The Development Of Colon Cancer

[...] y the age of 50, it is estimated that only a few percent of adenomas will progress to cancer. The study published as an advance online publication of Cancer Cell, describe a mechanism by which harmless colon polyps acquire the ability to form m [...]

Results of platinum-based chemo trials announced 2nd June 2008

[...] arian cancer and colorectal cancer. The phase one study looked at picoplatin and liposomal doxorubicin in patients with advanced solid tumours while the phase two trial examined patients with metastatic colorectal cancer. "The phase one trial i [...]

Cancer Prognoses Favor the Rich and Well-Educated

[...] impacts both tumor biology and socioeconomic status. Such cancer patients, commonly those with less education, had more advanced disease at diagnosis, got less aggressive treatment, and were more likely to die in the five years after diagnosis, [...]

Flavonols may slash colorectal cancer risk: study

[...] medication, they found that an increased intake of flavonols was linked to a 76 per cent reduction in the recurrence of advanced tumours. Lesser benefits were observed for increased intakes of kaempferol, found in Brussels sprouts and apples, a [...]

Major Gastroenterology Journal Accepts Version 2 Technology Study for Publication

[...] ol-based DNA detection for the millions of people who resist more invasive procedures.” “Demonstrating that certain advances in molecular diagnostics that we discovered in my lab and licensed to EXACT Sciences can directly contribute to ear [...]

KRAS developments and implementation of findings

[...] g that KRAS is not an independent prognostic factor. Applying the data to practice Based upon thess data, patients with advanced colorectal cancer should undergo tumor KRAS testing prior to receiving EGFR-targeted therapies. KRAS mutational sta [...]

Multiple means help screen for colorectal cancer

[...] cess and financial access are the biggest challenges in providing comprehensive screening for the population. There are advantages and disadvantages to the various screening strategies including cost, sensitivity, discomfort, time, and availabi [...]

What is sign for progressive of colorectal carcinoma?

[...] r. Adam Elzagheid from University of Turku of Finland examined alpha-catenin expression in a series of 91 patients with advanced colorectal carcinoma, and analyzed the relationship with clinical and pathological features of CRC patients. Archiv [...]

InNexus Biotechnology Announces New EGFR Antibody DXL1218 Targeting Colorectal Cancer and Announces US$1.25 Million Private Placement

[...] research partner InNexus. Jeff has had a vision for rapid product development based on DXL(TM) technology coupled with advanced in vivo studies and a significant regulatory strategy. We look forward to their continued rollout of products and p [...]

OncoVAX, Other Vaccines Provide Hope for Colorectal Cancer Treatment, Prevention

[...] NEW YORK, NY, Nov 13, 2008 (MARKET WIRE via COMTEX) — Propelled by advances in molecular biology, the treatment of colorectal cancer is on the verge of dramatic change and a promising future [...]

Bittersweet Gene

[...] survival of tumor cells and is often expressed at high levels on colorectal tumors. In patients such as Banks who have advanced disease and do not respond to standard chemotherapy, Vectibix and Erbitux can be beneficial. Recent studies have sh [...]

Alberta cancer board backs funding for costly drug

[...] e province. The board's pharmacy and therapeutics committee gave Avastin a positive recommendation for the treatment of advanced colon cancer after examining evidence at a hearing. The committee will now ask Alberta's new superboard to pick up [...]

Long-term Follow-up of Laparoscopic-assisted Versus Open Colectomy Trial

[...] ary 2009, issue of Lancet Oncology.[1] Laparoscopic surgery is used for many types of surgery and offers the short-term advantages of less pain, fewer wound complications, quicker post-operative recovery, and shorter hospital stays. However, th [...]

Simple Tests for Colon Cancer Underused, Study Says

[...] atients who have cancer precursor lesions, but the best of them could only identify about one out of four with the most advanced lesions.” But according to Dr. Allison, such percentages do not leave colonoscopy as the best screening technique [...]

Non-Invasive Colorectal Test Planned

[...] ting micoRNAs (miRNAs) in patients sera could be used to develop an effective screening test for colorectal cancer. The advantages of a blood based test for colorectal cancer compared to conventional colonoscopy procedures are obvious and could [...]

HORMONE REPLACEMENT THERAPY

[...] ring colonoscopy. However, a new study, just published in the journal Gastroenterology, reveals a potentially important advance in stool DNA testing for colorectal cancer screening. In this new study, PCR was combined with another test known as [...]

Immunochemical Fecal Occult Blood Tests

[...] widely in their ability to detect adenomas that were found with colonoscopy. Sensitivity and specificity for detecting advanced adenoma ranged from 25% to 72% and from 70% to 97% for the 6 qualitative immunochemical tests. The sensitivity and [...]

Non-Invasive Colorectal Test Planned

[...] ting micoRNAs (miRNAs) in patients sera could be used to develop an effective screening test for colorectal cancer. The advantages of a blood based test for colorectal cancer compared to conventional colonoscopy procedures are obvious and could [...]

Newer Immunochemical Fecal Occult Blood Tests Confirmed More Reliable Than Older Guaiac Tests for Detection of Colorectal Cancer

[...] or to colonoscopy. Thirty-one percent of patients had an adenoma found by colonoscopy, and 10% of these were considered advanced. These researchers found that all the immunochemical FOBTs were more accurate than the guaiac FOBT. They reported t [...]

Screening CT Colonography and Colonoscopy Similarly Effective

[...] colonography (CTC), also known as virtual colonoscopy, performs as well as traditional optical colonoscopy in detecting advanced adenomas in an average risk population, results of a study conducted in Germany indicate. Dr. Anno Graser from Univ [...]

Rent a giant colon

[...] ! The three-dimensional interior also features Ulcerative Colitis, Rectal Cancer, Diverticulitis, Crohn’s Disease and Advanced Stage Colorectal Cancer. While exploring The Giant Colon, visitors receive healthy lifestyle tips and explanations [...]

Potentially life-saving drug denied to cancer patients here

[...] anada, said in an interview there are now seven provinces providing a leading-edge drug called Avastin to patients with advanced colorectal cancer. He =aid New Brunswick's refusal to provide the drug, in addition to its lack of an effective scr [...]

Text size: increase text sizedecrease text size A healthy lifestyle and regular screening help fight colon cancer

[...] se and lymph nodes involved. Radiation therapy is typically not used in the treatment of colon cancer unless it is very advanced locally, or if the cancer could not be completely removed by surgery. When rectal cancer is advanced, the treatment [...]

Get Your Butt Over Here!

[...] e are to =ure cancer we must encourage new innovation and technology and ensure that =anadians have access to these new advances", said =tein Stein is referring to a new generation =f biologics and small molecules now approved by Health Canada [...]

Cancer patients win drug fight

[...] coupled with surgery, even find a cure,” he said. Health Canada approved the drug in 2005 for use in the treatment of advanced colorectal cancer, but Alberta rejected the drug from Medicare coverage, meaning cancer patients had to pay $2,000 [...]

Cancer patients win drug fight

[...] coupled with surgery, even find a cure,” he said. Health Canada approved the drug in 2005 for use in the treatment of advanced colorectal cancer, but Alberta rejected the drug from Medicare coverage, meaning cancer patients had to pay $2,000 [...]

Colorectal cancer: Issues and statistics

[...] d receive chemotherapy after surgery - sparing patients the side effects unless there's a potential benefit. In another advance, surgical techniques now enable doctors to attack even some complex cases of colorectal cancer with minuscule laparo [...]

Fighting for his life

[...] the cells in the body. Clinical trials have shown that Avastin is most effective when used as the initial treatment for advanced colorectal cancer, stated the ministry. A health ministry spokesperson said 12 Avastin cycles are the base treatmen [...]

Genomic Health Study Shows Breast Cancers in Men Display Very Similar Gene Signatures to Those in Women

[...] endent, prospectively-designed QUASAR validation study" (Abstract #4000), which was highlighted on May 14 during ASCO's advance presscast, will be presented Saturday, May 30 (3:00 p.m. ET). Genomic Health plans to make its colon cancer test ava [...]

The Life-Saving Secrets in Your Family Tree

[...] ry, especially the first time they see a new doctor, but the questions are often perfunctory. Without doing research in advance, patients might have little knowledge of medical conditions beyond their closest relatives. Patients should bring a [...]

What Is Colorectal Cancer? What Causes Colorectal Cancer?

[...] y develop colorectal cancer in Western Europe. 40% of people who are diagnosed with colorectal cancer are already at an advanced stage of the cancer. For these patients surgery is probably the most likely option. Colorectal cancer tends to affe [...]

Risky guts

[...] igger and can turn malignant (cancer). This process usually takes many years. Colon cancer has no early symptoms. At an advanced stage, however, signs may include alterations in bowel habits, eg diarrhoea or constipation with blood, lethargy, s [...]

Blacks With Equal Care Still More Likely to Die of Some Cancers

[...] cancer, 41 percent more likely to die from early-stage premenopausal breast cancer, 61 percent more likely to die from advanced ovarian cancer and 21 percent more likely to die from advanced prostate cancer. Because all the cancers for which t [...]

Colon Capsule Endoscopy Diagnoses 64% Of Total Polyps Detected By Conventional Colonoscopy

[...] ho download the images recorded on the computer. As regards the use of the capsule, conventional colonoscopy has the disadvantage of involving an invasive procedure, usually carried out with sedation or general anaesthetic and presenting risks [...]

borough president calls on national health care industry to bring drug research to the Bronx

[...] as never a quitter on the field, so I realized I couldn't quit." Strawberry has remained cancer free, attributing it to advancements in pharmaceutical research. "I'm living proof of the improvements in the medicine field," he said. Still, the p [...]

Methylation Test May Aid Colon Cancer Diagnosis

[...] test also yielded positive results in 41% of stool samples from patients with colon cancer and in 45% of patients with advanced colonic adenomas. DNA methylation has a well-recognized association with carcinogenesis. Regions of hypo- and hyper [...]

End-of-Life Care: Where Ethics Meet Economics

[...] ted physicians at Memorial Sloan-Kettering Canter Center in New York stating that “the standard treatment regimen for advanced colon cancer, which can include Erbitux [and Eloxatin and Avastin] in the mix, is close to $250,000 for 19-20 month [...]

Younger Americans overexposed to radiation risk

[...] S. markets between January 2005 and December 2007. CAT SCANS The two biggest contributors to radiation exposure were an advanced kind of X-ray called a computed tomography or CT scan and nuclear medicine scans — in which a small amount of [...]

Oasis Half Marathon

[...] well as increases the chances of catching the cancer at an earlier stage when it is most curable. There have been many advances in diagnosis and treatments but much more still needs to be done! We are trying to do our part in helping the fight [...]

Erbitux Significantly Increases Survival in 1st-Line Metastatic Colorectal Cancer Patients

[...] April 2006 (EU) and followed by other countries: for use in combination with radiotherapy for the treatment of locally advanced squamous cell carcinoma of the head and neck (SCCHN). In further countries, Erbitux is also approved as monotherapy [...]

New blood tests promise simple cancer detection

[...] l cancer at Rotterdam's Erasmus University, who was not involved in the research, said the new tests marked a promising advance in the field of developing more convenient screening. "The blood sample can be taken by nurses or primary care docto [...]

Adapting Capsule Endoscopy for Colorectal Cancer Screening

[...] of the capsule was not as high as colonoscopy (which is thought to have a maximum sensitivity of just over 90 percent). Advanced adenomas of any size were detected in 52 patients by colonoscopy, but in only 44 patients by CE. Nineteen cancers w [...]

Cancer Research UK chief executive reminds Conservative party conference of cancer priorities

[...] iagnosed with breast cancer are also likely to survive for at least 20 years. However, while Mr Kumar welcomed the many advances in recent years, he also cautioned against complacency. "Even though one in three of us will get cancer at some poi [...]

The bureaucracy of life and death

[...] stice, slams the Ontario government for acting in a way "that verges on cruelty" for people like Anderson who live with advanced colorectal cancer. It details Ontario's decision to put an arbitrary cap of 16 cycles of treatment on a drug called [...]

Study shows unsedated colonoscopy for colorectal cancer screening well accepted by patients

[...] colon; the other two-thirds are not examined. If polyps are found, the patient must return for a full colonoscopy. The advantages of unsedated colonoscopy include the elimination of the risks associated with sedation, especially in patients wi [...]

Colon Cancer Prevention Vaccine - Health News Story - WSOC Charlotte

[...] f Pittsburgh Cancer Institute are testing a vaccine that may help reduce the risk of developing cancer in patients with advanced adenomas, a type of polyp that carries a high risk of becoming cancerous. The vaccine under study targets a specifi [...]

Dread the Colonoscopy and Do It Anyway - FitcomHealth.com

[...] re fun than being diagnosed with cancer". Unfortunately, colorectal cancer is a stealthy and insidious disease, when it advances, oftentimes totally unknown to the patient, it can be a hard battle to fight. Contrastly, if potential problem area [...]

Predicting response of metastatic colorectal cancer to therapy using biological markers - The American Journal of Hematology / Oncology (AJHO)

[...] ts in cell growth regulator genes, such as KRAS, p53, APC, and DCC, affect signaling pathways, creating a clonal growth advantage that leads to proliferation of malignant cells.1 The PTEN/PI3K/AKT and the RAS/RAF/mitogen-activated protein kinas [...]

Colorectal Cancer patients in Alberta and Saskatchewan Get a New Sense of Hope Alberta and Saskatchewan announce that colorectal cancer treatment Vectibix(R) is now reimbursed by the government (re: Amgen’s panitumumab)

[...] recently announced that Vectibix(R) (panitumumab), the first and only fully-human monoclonal antibody for patients with advanced (metastatic) colorectal cancer, is now funded by both governments. A disease that affects the digestive system, col [...]

Simple test shows whether cancer drug will work - but NHS does not use it - Times Online

[...] is.” Sir John’s criticisms come six months after a House of Lords inquiry found that the NHS was not ready to take advantage of genetic advances in healthcare. He said that scientific developments since the report was published had made ac [...]

My doctors aren’t convinced - but I believe green tea cured my cancer

[...] n, four, made it seem worse,’ says Sam, a former advertising executive. ‘I couldn’t believe my cancer could be so advanced when I’d had an all-clear result from my smear the year before. But I was told that tests fail to detect cancer i [...]

Diane Balma: A Battle Close To Home: Thirty Eight Years After Nixon’s Declaration Of War

[...] an and must do better! We urgently need new screening tools in some cancers; better screening tools in others; and more advancements for the treatment, cure and prevention of all cancers and for everyone, regardless of age, ethnicity or demogra [...]

Follow-up colonoscopy often misused: studies | Reuters

[...] ams. The researchers also found that within 5 years of the initial colonoscopy exam, only 58.4 percent of patients with advanced precancerous growths had a follow-up colonoscopy, despite the recommendation that they do so every 3 years. "This i [...]

Colorectal Cancer Screening Approach Studied in Seniors

[...] mm thresholds, the per-patient positivity rates for adenomas were 10.9 and 6.8 percent, respectively. The prevalence of advanced neoplasia was 7.6 percent. Extracolonic findings of potential importance, such as vascular aneurysms, were noted in [...]

Malaria Drug Tested for Colorectal Cancer Use

[...] organs and has only an 11 percent, five-year survival rate for disease that has spread beyond nearby organs. It is the advanced state of disease that investigators at CINJ are targeting in this study. The standard treatment for colorectal canc [...]

’Giant colon’ aimed at promoting prevention of colorectal cancer, screening

[...] h Sciences Centre in Toronto, who sees too many patients whose newly diagnosed colorectal cancer has already reached an advanced stage. "We hope that they'll be aware that this is an important cancer." "One of our messages is you don't think ab [...]

Why you need this test

[...] cent of smaller ones. It's so thorough that rechecks are needed just once every 10 years if results are normal. Another advantage: Docs can remove polyps during the procedure. Virtual colonoscopy: Just as accurate. New research confirms that th [...]

Medical News: Colon Cancer Screening Practices Get Low Marks - in Hematology/Oncology, Colon Cancer from MedPage Today

[...] ary care physicians showed that 74% performed in-office tests on a single specimen, a strategy that misses up to 95% of advanced colorectal neoplasia (Ann Intern Med 2005; 142: 81-85). Moreover, 30% of respondents to that survey said they recom [...]

LIVE THIS DAY WITH HOPE!

[...] er. The doctor had then found me in glowing health. However, a brutal verdict fell: colorectal cancer stage 4, the most advanced. A life expectancy of about six months. An oncologist did not subsequently give me any hope of survival, which I fo [...]

A Multidisciplinary Approach to Cancer Detection and Treatment: What’s On the Horizon

[...] ents with early-stage prostate cancer and found circulating tumor cells in 42 percent of the patients. In patients with advanced prostate cancer, circulating tumor cells were found in 64 percent of the patients. The research team was also able [...]

Colorectal Cancer Association of Canada applauds Prince Edward Island’s decision to fund Avastin

[...] ratulates the Prince Edward Island government for making Avastin publicly accessible to colorectal cancer patients with advanced disease," said Barry D. Stein, president of the Colorectal Cancer Association of Canada(CCAC). "Patients in PEI wil [...]

What to eat to prevent cancer

[...] ving in Bangkok or Tokyo compared to a person living in Ontario. These huge differences are not the result of a genetic advantage, because Asians that move west see their risk of contracting these cancers rise to similar rates of the people liv [...]

How to Start a Colon Cancer Diet – Share This Info

[...] a man’s greatest preventative measure against developing serious or fatal diseases. Including our information of the advantages of a healthy diet and proper nutrition, how are we to start a colon cancer diet? Can this diet truly guarantee a [...]

Bacteria in gut could be predictor of colon cancer

[...] tient’s bacteria will not tell you as much as studying their intestinal cells. But the stool-based test does have its advantages over a colonoscopy. “The stool-based test is non-invasive, does not require anesthesia, would not have to be co [...]

Bacteria in gut could be predictor of colon cancer

[...] tient’s bacteria will not tell you as much as studying their intestinal cells. But the stool-based test does have its advantages over a colonoscopy. “The stool-based test is non-invasive, does not require anesthesia, would not have to be co [...]

New Study Demonstrates Value of ColonSentry(TM) as Pre-Screening Alert to Enhance Effectiveness of Colorectal Cancer Screening

[...] ons could increase the effectiveness of colorectal cancer screening by revealing the potential presence of neoplasms in advance of colonoscopy," said Dr. Robert Burakoff, one of the investigators for the reported study, Clinical Chief of Gastro [...]

Blood-Based Pre-Screener May Aid Colorectal Cancer Testing

[...] ons could increase the effectiveness of colorectal cancer screening by revealing the potential presence of neoplasms in advance of colonoscopy," said Dr. Robert Burakoff, one of the investigators for the reported study, clinical chief of gastro [...]

Possible Red Flag to Predict Colorectal Cancer Identified

[...] st colonoscopy between June 2005 and May 2008. LSPs were defined as those at least 10 mm in size. The researchers found advanced neoplasia in 15.4 percent of patients, CRC in 6.9 percent, and LSPs in 1.4 percent. Multivariate analysis showed th [...]

Serrated Polyps Together With Adenomas Raise CRC Risk

[...] onoscopies. The findings were presented at the annual meeting of the American College of Gastroenterology. Adenomas and advanced serrated polyps (ASPs) are both precursors to colorectal cancer via different molecular pathways, said Dr. Carol Bu [...]

Modern living and diets feeds rise in bowel cancer in Asia

[...] sfully treated. According to Sham, in most cases symptoms such as changes in bowel habits only occur when the cancer is advanced which means around 50 to 60 per cent of all cases result in death. Studies have shown that bowel cancer occurs pred [...]

Low Bowel Cancer Awareness In UK

[...] sical exercise reduces the risk of developing polyps by 16%, but more crucially, that it reduces the risk of developing advanced or large polyps by 30%. The researchers weren't able to say exactly how exercise does this, but they suggested it c [...]

Can high-fiber diets possibly shrink colon polyps?

[...] intile. The inverse association was strongest for fiber from grains and cereals and from fruits. Risks were similar for advanced and non-advanced adenoma." The study noted that, "Risk of rectal adenoma was not significantly associated with fibe [...]

Study links desk jobs to bowel cancer risk

[...] ors for this type of cancer. The researchers say their findings have occupational health implications, especially since advances in technology have led to increasing amounts of sitting at work. Conclusion This is a well-conducted study, using c [...]

Do Men Need Colon Cancer Screening Earlier Than Women Do?

[...] "In our study, analysis of age- and sex-specific prevalence of adenomas, advanced adenomas and colorectal cancers indicates a significantly higher rate of these lesions among men compared with wome [...]

Researchers’ breakthrough may change cancer therapy

[...] y. Doctors have largely relied on biopsied tissue that is frozen or set in wax to diagnose and recommend treatment. The advance has sparked new hope that someday doctors may be able to test a host of cancer-killing drugs on a person's own tumou [...]

Oncozyme Pharma

[...] rch going, which inevitably leads to testing medicines in a clinical setting. Studies on voluntary patients allow us to advance our knowledge on cancer. However, the low rate of participation in such clinical studies by eligible patients poses [...]

Little-used PET scanners can detect cancer earlier

[...] nd changes in patient management don’t always improve patient survival. Many times PET reveals cancer to be at a more advanced stage and gives patients the option of choosing palliative care. It isn’t the best outcome, but PET’s informati [...]

Area cancer patients wait longer for treatment, report finds

[...] that despite a major infusion of cash to expand provincial cancer screening programs, far too few Ontarians are taking advantage of them. For example, half of all eastern Ontarians who should be screened for colorectal cancer are not taking ad [...]

Colon Cancer Research: Time To Learn From Mistakes

[...] l (DFS) or overall survival (OS). According to Dr. Sobrero, researchers were mistaken to believe that what works in the advanced setting will work in the adjuvant setting, as well as to believe that the greater the risk, the greater the benefit [...]

Simpler colon screen may be enough for many women: study

[...] and up who underwent a colonoscopy. They found that among women younger than 70, only one percent had either a tumor or advanced polyp - a growth that could become cancer - in the upper part of the colon. That was half the rate seen among men t [...]

FREE EDUCATIONAL SEMINAR ON MANAGING COLORECTAL CANCER

[...] rectal cancer is the second leading cause of death from cancer in Canada. It’s time to shine a light on the impact of advanced colorectal cancer on patients and their families and caregivers. Don’t miss the chance to join experts and attend [...]

FREE EDUCATIONAL SEMINAR ON MANAGING COLORECTAL CANCER

[...] rectal cancer is the second leading cause of death from cancer in Canada. It’s time to shine a light on the impact of advanced colorectal cancer on patients and their families and caregivers. Don’t miss the chance to join experts and attend [...]

Heat Generated To Kill Colorectal Cancer Cells Via New Electrically-Conductive Polymer Nanoparticles

[...] infrared light, the treatment killed up to 95 percent of cells. "The results of this study demonstrate how new medical advancements are being developed from materials science research," said Levi-Polyachenko. The team made polymer nanoparticle [...]

Studies

[...] ew medications for cancer treatment. They are hoping to gain a better understanding of the experiences of patients with advanced cancer. The feedback from these interviews will help them better understand patients’ experience with advanced ca [...]

“Network of networks” will bolster clinical registries

[...] unds to enlist the participation of physicians, patients and health care systems in building a national data network to advance research comparing the effectiveness of different treatment options on the same conditions. PCORI is a nonprofit, in [...]

Dietary Intakes of Red Meat, Poultry, and Fish During High School and Risk of Colorectal Adenomas in Women

[...] al (OR = 0.80, 95% CI: 0.64, 0.99), distal (OR = 0.71, 95% CI: 0.51, 0.99), rectal (OR = 0.51, 95% CI: 0.29, 0.90), and advanced (OR = 0.60, 95% CI: 0.38, 0.93) adenomas. Replacement of 1 serving per day of red meat with 1 serving per day of po [...]

Holland’s Research Focuses on Needs of Older Patients

[...] shed in 2006.1 What was the design of the study? One hundred ninety-two older patients who were receiving treatment for advanced breast, prostate, or colorectal cancer were randomized to receive either printed educational materials alone, or ed [...]

Novel Genetic Patterns May Make Us Rethink Biology and Individuality

[...] that each person contains only one DNA sequence (genetic constitution). Only recently, with the computational power of advanced genetic analysis tools that examine all the genes in one individual, have scientists been able to systematically lo [...]

Canadians are still frustrated at lack of affordable access to new cancer medicines

[...] ivers and the colon cancer community - both treatments represent viable new options for colorectal cancer patients with advanced disease. Timely approval of and affordable access to effective new medications is an important issue for Canadian p [...]

What Are the Benefits of Minimally Invasive Colorectal Surgery?

[...] ng colonoscopy for the increased detection of smaller colon tumors, which are more easily removed laparoscopically than advanced lesions that have spread beyond the colon to surrounding organs or structures. Colonoscopy use over the past decade [...]

Mission

[...] n the field of colorectal cancer, provides counsel to the CCAC to ensure members are kept abreast of the latest medical advances in the diagnosis and treatment of the disease. The mandate of the CCAC is threefold: awareness, support, and advoca [...]

CT Scanning May Predict Survival in Colorectal Cancer Patients

[...] e surgical implications, as it might be possible in the future to propose more aggressive surgery in patients with more advanced disease, yet who are classified as having a major response, based on these radiological findings." Source: Universi [...]

Quebec has a unique opportunity to lead the way in the prevention and treatment of colorectal cancer

[...] r years that we could have prevented thousands of Quebecers from getting this disease, do we deprive them from the most advanced treatments in accordance with prescribed treatment guidelines? "We are at a crossroads in Quebec where the cost of [...]

What is Colorectal Cancer

[...] etermined, they are combined to form and overall stage of the cancer in roman numerals, the higher the number, the more advanced the cancer. This is generally how the cancer is referred to between doctor and patient: 0 - The cancer is confined [...]

Colorectal Cancer Statistics

[...] rectal cancer are consistent at 68% among people diagnosed between the ages of 15 and 69 years; RSRs then decrease with advancing age. Geographics The incidence of colorectal cancer in Canada is highest for men and women in Newfoundland and Lab [...]

New Treatments for Colorectal Cancer

[...] l cancers. However, with the advent of targeted therapy, customized treatment is one step closer to a cure and each new advance is making the reality of turning colorectal cancer into a chronic disease. Monoclonal antibodies and other targeted [...]

The Real Story

[...] or the nurses constantly coming onto me I'm not sure I'd like to go back. Suzanne has been very good about their sexual advances though and bravely turns a blind eye. She is only thinking of my health. What a trooper. For those of you who have [...]

Dignity and respect are the norm here.

[...] see a doctor as the need arises, and knowing our provincial or territorial plan will cover the costs. Another Canadian advantage, particularly for people who have been diagnosed with serious medical problems, is the opportunity to get a second [...]

It’s time for Ottawa to pay the cancer piper

[...] Canada’s equity and venture capital market. An American company invested $250 million last year to help Air Canada “advance its plan to emerge from bankruptcy protection.” By the end of this year, Canada will have contributed $250 million [...]

Colorectal Cancer Patients Charter

[...] ially important in a time when the overall number of patients is increasing as our population ages, even as incremental advances in screening and treatment are contributing to better overall survival rates. Although this document is written wit [...]

Surgeons

[...] fessional society representing more than 1000 board certified Colon and Rectal surgeons and other surgeons dedicated to advancing and promoting the science and practice of the treatment of patients with diseases and disorders affecting the colo [...]

Keri’s Tournament of Hope and Awareness

[...] ciation of their kind dedicated to all of the above efforts, and also the most productive. However even with all of the advances made in the treatment of colorectal cancer people like Keri are still losing this battle. Keri, an avid ball player [...]

FDA APPROVES ELOXATIN FOR COLORECTAL CANCER

[...] available under new drug applications designated as "Fast Track." Drugs in development that have the potential to be an advance in treatment for a serious illness may be identified as "Fast Track" drugs. Under this designation, rolling applicat [...]

Traveler’s Diarrhea Bug May Help Treat Colon Cancer

[...] he toxin. Waldman added that the ST appears to only curb the spread of colorectal cancer, so patients whose cancers are advanced enough to spread to other parts of their bodies would likely have to use other chemotherapy treatments as well. "Th [...]

Going South for Health Care

[...] e to be a lawyer like Stein to get it—anybody can find the specialist he or she needs, or gain access to the most advanced technology available. Some strategies may require your ingenuity and persistence, while others will require you to [...]

Success of chemotherapy tied to genetics

[...] n, Cohen and Batist, who are also professors in the Faculty of Medicine at McGill University, analyzed 43 patients with advanced colorectal cancer. All patients were administered fluoropyrimidine-based chemotherapy. Tumour progression and survi [...]

Success for New Cancer Drug

[...] unusual step of accepting the Avastin paper as a last-minute submission, prohibits scientists from releasing details in advance. But Dr. Desmond-Hellmann said in an interview that survival was extended by more than the two to three months that [...]

New drug cuts chemo nausea

[...] works with current treatments that target a different family of receptors. Aprepitant "really is the first substantial advance that we've had in the prevention of nausea and vomiting related to chemotherapy in almost a decade," said Paul Heske [...]

AAFP: Women Not Receiving Optimal Colon-Cancer Screening in U.S.

[...] local disease, regional disease and distant disease. The study determined that women tended to be at the upper, or more advanced, end of the disease. "This is significant," said Dr. Woods, "because the regional disease, which significantly affe [...]

Colorectal Consensus Conference on the Treatment of Colorectal Cancer

[...] al at 3yrs was 77.8% vs. 72.9% (p Although this data was thought to be interesting, pending demonstration of a survival advantage, the standard for adjuvant therapy remains 5FU modulated with leucovorin. 3. Regional therapies in the management [...]

Colorectal Consensus Conference on the Treatment of Colorectal Cancer

[...] al at 3yrs was 77.8% vs. 72.9% (p Although this data was thought to be interesting, pending demonstration of a survival advantage, the standard for adjuvant therapy remains 5FU modulated with leucovorin. 3. Regional therapies in the management [...]

Sanofi Synthelabo Oxaliplatin

[...] easing their symptoms. Combined with 5-FU and leucovorin, it is an effective first or second line treatment that offers advantages over current platinum compounds. For Canadian patients, it is accessible through the Special Access Program overs [...]

COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS; HNPCC

[...] noma/carcinoma sequence in this disorder. Chromosome 18 sequences were lost frequently in colon carcinomas (73%) and in advanced adenomas (47%), but only occasionally in earlier stage adenomas (11-13%); see 120470. Chromosome 17 sequences were [...]

Study: Vitamin D cuts colon cancer risk

[...] esearch that found that cereal fiber and regular use of pain relievers such as aspirin and ibuprofen reduce the risk of advanced polyps and that smoking, heavy drinking and a family history of polyps raise the risk. Diets high in calcium have b [...]

Cancers of the Gastrointestinal System

[...] chat on Cancers of the Gastrointestinal System, covering topics such as: - New therapeutic strategies - Treatments for advanced cancer - Latest efforts in the prevention and screening of gastrointestinal cancers Preregistration is not required [...]

Rectal Cancer Treatment Lags, Especially for Blacks

[...] rican-Americans with rectal cancer were diagnosed at a younger age than whites, and were more likely to have reached an advanced stage of cancer progression before their cancer was caught. They were also more likely than whites to have a kind o [...]

’Why not me?’ - cancer survivor

[...] n such bad shape, she couldn't sit down: "The pain was so bad I had to stand up to study." When she got the diagnosis - advanced colorectal cancer, Stage 3 - it came as a relief to finally put a name to her illness. Today, the soft-spoken Elder [...]

FDA Approves Avastin (Bevacizumab, rhuMAb-VEGF) for Treatment of Metastatic Colon or Rectal Cancer

[...] ectal cancer patients which demonstrated that patients treated with Avastin plus IFL chemotherapy had a median survival advantage close to five months, compared to patients on chemotherapy alone (20.3 months versus 15.6 months). This represents [...]

The Odyssey Of A Cancer Drug

[...] l growth, was a biotech star. A clinical trial found that Erbitux shrank or stabilized tumors in 22.5% of patients with advanced colon cancer, a strong result for a cancer drug. That September, Bristol-Myers Squibb Co. paid $2 billion for a 20% [...]

Living Through Colorectal Cancer

[...] dad makes the most of every day he has and he has taught his family to do the same." Tickets for Cure-osity are $10 in advance, $15 at the door. Visit www.cure-osity2004.com or call 340-8251. For info about CCAC visit www.ccac-accc.ca. Informa [...]

Burns vowing to beat cancer

[...] on coaching the Devils in the first round even though the treatments would not have allowed him to coach had the Devils advanced. Burns appeared at the news conference at Continental Airlines Arena with his wife Line and with Devils general man [...]

FDA, Genentech issue Avastin warning

[...] ects," as reported in MSN Money. Some medical experts said that they didn't think the warning would deter patients with advanced colon cancer from using Avastin, but it could result in physicians limiting their prescribing of it more widely, as [...]

Xeloda improves therapy of patients with early colon cancer

[...] precedented four marketed products with survival benefit in different major tumour indications: Xeloda and Herceptin in advanced stage breast cancer, MabThera in non-Hodgkin's lymphoma, and Avastin in colorectal carcinoma. In the United States [...]

Stony Brook University Medical Researcher Developing New Medication To Prevent Colon Cancer

[...] Cancer Society. In order to arrive at a more accurate diagnosis in less time, Dr. Rigas and his colleagues are using an advanced imaging technique called magnifying endoscopy to examine the growth of the earliest recognizable lesions, known as [...]

Bottoms up for Colonoscopy

[...] ical condition), it wasn't exactly met with unbridled enthusiasm. (Luckily, it was fall and there were no flies to take advantage of my dropped-to-the-floor mouth.) That said, I knew there was no way around it. The benefits were inestimable, ma [...]

Calcium May Protect Women From Cancer

[...] more than $80 million in peer-reviewed grants during fiscal year 2003, the Cancer Center conducts cancer research that advances knowledge and enhances care. The center also engages community outreach and public education efforts addressing can [...]

Important discovery about colorectal cancer

[...] An international team of medical scientists has made an important advance in our understanding of the second most fatal form of cancer in the industrialized world. Professor Jeremy R. Jass, [...]

Free seminar on colorectal cancer at Milton Hospital

[...] y, University of Toronto, and Co-Director for Cancer Genetics Centre, Samuel Lunenfeld Research Institute, will present Advances in Colorectal Cancer Research. Their presentations will be followed by question and answers. This free seminar will [...]

Comedy benefit aims to reach people - seriously

[...] auzon, Ed Sahely, Debra McGrath, Jayne Eastwood, Robin Duke and Teresa Pavlinek. Tickets are $35/$25 at the door, or in advance through Ticketmaster.ca or by calling 416-872-5555. TorontoSun.ca [...]

Protective effect of calcium in reducing colon cancer polyps lasts for years

[...] cent overall reduction in polyp formation among participants who used the calcium supplements. The reduction in risk of advanced adenomas - more worrisome polyps with a closer association with cancer, was even larger at 28 percent. The findings [...]

Identifying Patients at Risk of Colorectal Cancer with Revised Bethesda Guidelines

[...] y MSH2 and MLH1. In HNPCC, colorectal tumors have a DNA abnormality called microsatellite instability. Although a great advance in the understanding of the molecular basis of HNPCC has taken place in the last decade, optimal selection of indivi [...]

Health Canada responds to Expert Advisory Panel on COX-2 drugs

[...] ssed by the quality of the report, but also by the fact that the panel has made important suggestions that will further advance our plans for making important health and safety information more accessible," the Minister said. Health Canada will [...]

Report: Chinese have high rate of colon cancerAmong Asians, ethnic group most prone to polyps and disease

[...] and Bangkok. Among ethnic Chinese examined in the survey, researchers found those in Hong Kong the most susceptible to advanced colorectal polyps and cancer — 11 percent of them were diagnosed with the condition. Eight percent of Chinese [...]

Paying the price for treatment:

[...] rst drug oncologists reach for, using it in almost all cases of colorectal cancer that has spread. Some are using it in advanced lung-cancer patients; it's also being studied in patients with pancreatic, ovarian, breast and prostate cancers. In [...]

Fecal DNA Biomarkers for the Detection of Colorectal Neoplasia: Attractive, but Is It Feasible?

[...] Center and B. Rappaport Faculty of Medicine, Technion, Haifa, Israel (GR) Because of the high mortality associated with advanced disease, accessibility to direct visual examination, extensive research, and recognition of the genetic mechanisms [...]

Chemotherapy, Radiation and Rectal Cancer Pre-surgical Treatment Improves Sphincter Preservation

[...] are large or difficult-to-reach by a surgeon. In the study, Crane and his colleagues reviewed 403 treatment records for advanced rectal cancer patients treated between 1978 and 1995. The patients were cared for at M. D. Anderson and Washington [...]

Inflatable colon tells tale of cancer

[...] seases are featured inside, including rectal and colon cancer. Dr. Oliver Bathe, a Calgary physician who specializes in advanced colorectal cancer, says the giant colon is surprisingly anatomically correct. Stein admits that the display is a pu [...]

Baby Aspirin Prevents Precancerous Condition

[...] uction in those taking the higher dose aspirin Even more significant, Dr. Bresalier says, was that the relative risk of advanced adenomas (lesions more likely to be precursors to cancer), was reduced by 41% in those taking low-dose aspirin. Sti [...]

The Inside Story - Some gambles are better than others.

[...] d how you can take better care of yourself. A cancer survivor, Stein agrees that a conventional colonoscopy has a major advantage: polyps can be immediately removed. "But I'm not knocking the value of virtual." I was able to get an appointment [...]

Mayo part of $21 million colon cancer research

[...] nd lifestyle factors involved in colon cancer. Selenium and cancer Mayo's part in the study springs from the preventive advantages of colon screenings. "Colorectal cancer screenings are different," said Dr. Russell Heigh, the Mayo gastroenterol [...]

New At-Home Test Screens For Colon Cancer

[...] e screening tool called the fecal immunochemical test, or FIT, is turning heads in the medical community because of its advanced technology and ease of use. "It takes maybe five minutes out of your time per day, three days in a row, and the res [...]

Colorectal cancer a deadly stalker

[...] population - has actually declined somewhat since the 1970s. The death rate has dropped as well, reflecting two trends: advances in treatment and catching the disease at earlier stages thanks to colonoscopies and the fecal occult blood test. St [...]

Human Genome Says Cancer Drug Safe

[...] During the study, patients with advanced colorectal cancer were given the HGS-ETR1 drug to evaluate tumor response. The company did not provide information [...]

Nine changes could save 2.5 million lives

[...] ing the death toll, their benefits are limited by cost and the difficulty of getting access to them in many countries. "Advances in cancer treatment have not been as effective as those for other chronic diseases. Primary prevention through life [...]

Colon cancer test is promising

[...] n detect an altered gene associated with colorectal cancer from 50 percent to 65 percent of the time, in both early and advanced cancer. It's the first blood test for colorectal cancer to deliver such promising results, said Dr. William Grady o [...]

NDP Health Critic Dave Wilson Calls for Regular Colorectal Cancer Screening

[...] However the National Committee estimates the lifetime risk of colonoscopy-related death to be only 0.005% and that the advantages far outweigh the risks. "Routine colorectal screening in not standard practice in this province and it should be, [...]

Chewing after colon surgery helps recovery: Study

[...] s. "So it's more expensive, it's more uncomfortable, it's away from their home and their work, so there's a lot of advantages to being able to eat and leave the hospital earlier." [...]

ASCO-GI: Serotonin Receptor Agonist Blocks Neuropathy in Colon Cancer Therapy

[...] to 37.8%, and the incidence of fatigue decreased from 3.7% versus 1.5%. "We've come a long way in the treatment of the advanced colon cancer patients," commented Nicholas Petrelli, M.D., of the Helen F. Graham Cancer Center in Newark, Del. "We [...]

Healthcare Consumers Gain Direct Access to Colon Cancer Detection DNA Test Via the Internet Through DNA Direct

[...] -the-art test that simply and safely eliminates the discomfort and inconvenience associated with the screening process. Advances in genetic research have led to the development of a non-invasive test that detects changes in DNA shed from colore [...]

Researchers Find Means Of Isolating Vitamin D’s Cancer-Fighting Properties

[...] drug would not be a cure for colon cancer. He says, "That's because we know that by the time colon cancer is well advanced it fails to respond to vitamin D." The study appears in the latest issue of the journal Molecular Cell. [...]

Gov’t won’t fund cancer drug

[...] ursday when Health Minister Len Taylor announced the province won't cover the cost of Avastin, a drug for patients with advanced colorectal cancer that costs about $2,000 per treatment. Taylor said the government made the decision on Avastin ba [...]

Dangerous divide

[...] cology products and patients. While treatments average $2,000 each and must be given every two weeks, these people have advanced diseases. So while 100 people may qualify in the beginning, that's not how many will be on the treatment. For some [...]

Targeted Therapies Showing Great Promise Against Colorectal Cancer

[...] prevent and cure cancer. Founded in 1907, AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes more than 24,000 basic, translational, and clinical researchers; health c [...]

Improving the odds of survival

[...] ancer screening, but it could be doing better. "There are some huge opportunities in screening for cancer. We're taking advantage of some of them, but not all," he said in an interview. Dr. Schacter said the one area where Canada is really lagg [...]

More cancer screening could reduce deaths: report

[...] sts tens of thousands of dollars to pay for drugs for colorectal cancer patients. "The number of Canadians who had advanced colon cancer and require all these new treatments would drop considerably," he said. "If you are looking [...]

Intracel and FDA Agree on Pivotal Phase III Clinical Protocol for Colon Cancer Vaccine

[...] eted Phase I/II studies in melanoma, renal and ovarian cancer, and the current clinical study paves the way for further advanced clinical development of the OncoVAX vaccine for these other types of cancer, as well." Some Background on Colon Can [...]

McGuinty Government Launches New Health Human Resources Strategy

[...] and their commitment to team-based health care -� Holding a summit in June to bring industry leaders together to advance the agenda of inter-professional education and care delivery -� Funding a new fully inter-professional curric [...]

How Drug Cocktails Are Changing the Way We Treat Cancer

[...] ir lab cupboards are plenty full of just such compounds. So far, the best cocktails, still in early testing in the most advanced cancer patients, try to include some agents aimed at cutting off a tumor's blood supply (so-called angiogenesis inh [...]

FDA gives priority review to Amgen drug

[...] FDA grants priority review status to treatments and drugs that have the potential to provide a significant therapeutic advance for patients, the company said. Instead of the usual 10 to 12-month review process, panitumumab will be reviewed in [...]

Dispute blocks cancer drug

[...] d medicines to ensure they are not excessive. The Cancer Advocacy Coalition of Canada estimates the drug, used to treat advanced cases of colorectal cancer, costs about $56,000 for a standard course of therapy. At the same time, the Ontario gov [...]

Colorectal Cancer Patients Suffer From Psychological Problems Long After Completion Of Treatment

[...] of colorectal cancer are diagnosed each year. This makes colorectal cancer one of the most common cancers in the world. Advances in early detection and treatment have improved prognosis substantially over the past decades. Long-term studies inv [...]

Researchers Reveal Possibility of Separating Anticancer Properties of Vitamin D (press release)

[...] therapeutic benefit for later stage cancers, Byers said. "That's because we know that by the time colon cancer is well advanced it fails to respond to vitamin D." [...]

Anger at bowel cancer drug ruling

[...] Charities have criticised a proposal to block the routine NHS use of two drugs for advanced bowel cancer. The National Institute for Health and Clinical Excellence (Nice) said there was insufficient evidence [...]

Exercise may have benefits in colon cancer

[...] antly less likely to die of their cancer or of any cause. In another study, Meyerhardt's team studied 832 patients with advanced colon cancer who underwent surgery and chemotherapy with "curative intent." The subjects reported their recreationa [...]

Patients Prefer Conventional Colonoscopy

[...] ectal exam. Colonoscopy (optical colonoscopy) is a procedure in which a lighted tube is inserted through the rectum and advanced through the entire large intestine. The physician performing the procedure is able to view the colon on a screen. I [...]

Colon Cancer Alliance Launches Interactive Support Program for People Battling Colorectal Cancer

[...] alogue with thought-leading physicians in the area of colorectal cancer on a range of topics, from the latest treatment advances with targeted therapies to managing their side effects. In addition, patients and caregivers will have the opportun [...]

A strong band of women with Hart

[...] em. Her story is as compelling as it is terrifying. After repeated trips to the emergency room, Hart was diagnosed with advanced stage colon cancer when Sophie was 5 months old. The disease, which doesn't run in her family, had spread to her le [...]

Wellwood presents Prevention of Colorectal Cancer

[...] ctator and Ortho Biotech. Support programs Wellwood also runs a Living Well with Cancer support program, for those with advanced diagnoses, recurrences or metastases. The program runs for five weeks beginning Monday, Sept. 25. Evening workshops [...]

FDA Approves a New Drug for Colorectal Cancer, Vectibix

[...] director of FDA's Center for Drug Evaluation and Research. "This approval adds a treatment option for patients with an advanced stage of a disease that can be life-threatening." FDA approved Vectibix on the basis of the results of a randomized [...]

Smart Talk About Cancer From

[...] atch Memorial Sloan-Kettering experts — Dr. Winawer, Dr. Saltz, and Dr. Weiser — as they discuss the latest advances in the screening, diagnosis, and treatment of colorectal cancer. You'll need the Windows Media Player which can be [...]

Colon med for lung cancer

[...] be used in combination with carboplatin and paclitaxel chemotherapy as a first-line treatment for unresectable, locally advanced, recurrent or metastatic, non squamous, non-small cell lung cancer, the Associated Press reported. This is the most [...]

Cancer Survivor Critical of Gov’t Practices

[...] orectal cancer himself, says if governments hadn't funded some of the new and innovative childhood leukemia treatments, advances wouldn't have been made to find what amounts to a "near cure." [...]

Virtual scans as good as regular colonoscopy

[...] like optical colonoscopy but rather to attract those who are currently not being screened at all," Pickhardt said. "The advantages of virtual colonoscopy over optical colonoscopy at our institution are that it is safer, faster, less costly, mor [...]

Cancer Survivor Critical of Gov’t Practices

[...] orectal cancer himself, says if governments hadn't funded some of the new and innovative childhood leukemia treatments, advances wouldn't have been made to find what amounts to a "near cure." [...]

Genetic Variation Impacts Aspirin’s Effectiveness In Preventing Colon Cancer, Dartmouth Study Finds

[...] he ODC genetic variation were 23 percent less likely to develop new adenomas and 49 percent less likely to develop more advanced lesions, which also lead to cancer. ### This study was funded by the National Cancer Institute. Other authors on th [...]

Colon cancers 73% more common in men, says research

[...] mine their risks for colorectal cancer, especially if they have a family history of the disease, a study has suggested. Advanced neoplasia – a condition where precancerous polyps have grown large enough to result in cancer, was 73 percent [...]

Cancer linked to low folic acid levels

[...] eadly cancer after lung cancer. Dr. Sharlene Gill, a medical oncologist at the B.C. Cancer Agency, lauded the study for advancing medicine's understanding of folic acid's role in tumour prevention. But she noted that unlike the mice in the stud [...]

Stem cells the core of colon cancer: study

[...] h of these colon cancer stem cells to truly cure the disease." The researchers' findings were published yesterday in an advance online edition of the journal Nature. Stem cells are the building blocks of all blood and tissue in the body. Cancer [...]

Stem cells the core of colon cancer: study

[...] h of these colon cancer stem cells to truly cure the disease." The researchers' findings were published yesterday in an advance online edition of the journal Nature. Stem cells are the building blocks of all blood and tissue in the body. Cancer [...]

Provincial drug disparity a roadblock to cancer research

[...] can't play. "Not only are we screwing our patients by not offering them the standard of care, the only way we can make advances is by running these clinical trials," Ralph Wong, a medical oncologist at St. Boniface General Hospital in Winnipeg [...]

Screening could cut cancer deaths

[...] ar programs, while Ontario is the first jurisdiction in North America to start the screening. "It's an excellent, major advance in the battle," said Mr. Stein, a survivor of the disease who underwent nine surgeries. You should talk to your fami [...]

Med BioGene Enters Development Phase for Genetic Screening Test for Colorectal Cancer

[...] sitioned to develop this much needed tool" concluded Mr. Broshko. About Med BioGene MBI is a biotechnology company with advanced research and development in gene expression technology. MBI intends to utilize its expertise in gene expression to [...]

Royalmount Pharma and US National Cancer Institute Initiate Colorectal Cancer Biomarker Trial

[...] nd nonpolyposis syndromes. The high mortality of colorectal cancer is mainly due to the fact that patients present with advanced disease, thus making the case for preventive strategies. The current standard of care to prevent colorectal cancer [...]

Expanded trial for Clavis Pharma

[...] ting on Clavis Pharma's decision, Cassidy said: "Despite continuous efforts over the last decade to offer patients with advanced colorectal cancer new therapies, current results are highly unsatisfactory with five-year survival rates in the 10 [...]

Screening can be a lifesaver

[...] t in only one-third of patients. If the government makes testing better and more available, the least we can do is take advantage of it. Embarrassment is just, well, dumb. It involves our "bottoms" and our poop. Let's get over it, talk about it [...]

Cancer Surgery at Carolinas Medical Center: `Hot and fast’ tumor removal

[...] A surgeon at Carolinas Medical Center performed the first microwave surgery in the Carolinas this week to treat advanced liver cancer in a 48-year-old Charlotte man. Dr. David Iannitti, who was recruited to Charlotte last year from Brow [...]

Screening could cut cancer deaths

[...] ograms, while Ontario is the first jurisdiction in North America to start the screening. "It's an excellent, major advance in the battle," said Mr. Stein, a survivor of the disease who underwent nine surgeries. You should talk to your [...]

Diet, lifestyle affect colorectal adenoma recurrence

[...] Society Task Force on Colorectal Cancer and the American Cancer Society. These guidelines recommend that people with an advanced adenoma or three or more adenomatous polyps should undergo repeat colonoscopy in three years. The issue, according [...]

Liver Metastasis Remains a Major Threat to Cancer Survivors

[...] cancer patients. In most cases however, the disease is currently not curable. Researchers at NFCR believe that with the advancement of technology and ever-growing knowledge about this disease, major improvements in the treatment of colon and me [...]

FDA Warns of Possible Bevacizumab...

[...] m. It's also approved, with carboplatin and paclitaxel, for first-line treatment of patients with unresectable, locally advanced, recurrent or metastatic non-squamous non-small cell lung cancer (NSCLC). [...]

Coffee Drinking No Longer So Controversial

[...] drinking, panel chair Dr. James Coughlin, a toxicology/safety consultant at Coughlin & Associates, says that recent advances in epidemiologic and experimental knowledge have transformed many of the negative health myths about coffee drinkin [...]

Mixed News from DNA’s Avastin Studies

[...] ual meeting on Saturday in Chicago, Genentech's (DNA 79.50) Avastin doubled progression-free survival for patients with advanced kidney cancer when used in combination with a standard treatment for kidney cancer. This is good news for Avastin, [...]

Business booming at private endoscopy centre

[...] his week, although it opened its doors in July 2006. Since then a steady stream of patients, totalling 2,088 have taken advantage of the services offered at the clinic. "The day we opened, we probably started off with a month already in,&q [...]

Too much folic acid may be harmful to some

[...] of a second round of colonoscopies a few years later were more troubling. Among the folic-acid takers, 11.6 percent had advanced adenomas while 6.9 percent of the dummy-pill group did. And folic acid more than doubled the risk of having three o [...]

Blood Test Screening for Colon Cancer?

[...] tested, researchers correctly identified 96.2 percent of individuals with normal colons and 77.8 percent of people with advanced precancerous polyps. Dr. Getzenberg said they hope to make this method available in the next two years, but more re [...]

Health Canada approves new chemotherapy treatment for patients with metastatic colorectal cancer

[...] quot; says Dr. Scot Dowden, a medical oncologistwith the Tom Baker Cancer Centre in Calgary. "This is an important advance inthe management of metastatic colorectal cancer." About Eloxatin(R) Eloxatin(R) is one of the first treatments [...]

Too much folic acid not good in cancer study

[...] of a second round of colonoscopies a few years later were more troubling. Among the folic-acid takers, 11.6 percent had advanced adenomas while 6.9 percent of the dummy-pill group did. And folic acid more than doubled the risk of having three o [...]

Fat Kills Cancer: Turning Stem Cells Taken from Fat Tissue into Personalized, Cancer-Targeted Therapeutics

[...] prevent and cure cancer. Founded in 1907, AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes nearly 26,000 basic, translational, and clinical researchers; health care [...]

Diet points to cancer prevention

[...] y brought on by alcohol. Women drinking three or more cups of coffee a day were found to have a 56 percent less risk of advanced cancer forming in the colon—the largest part of the large intestine—than women who rarely drink coffee. [...]

Use of Calcium and Magnesium Salts to

[...] infusions: A retrospective study of 161 patients receiving oxaliplatin combined with 5-fluorouracil and leucovorin for advanced colorectal cancer. Clin Cancer Res 10:4055-4061, 2004 DOI: 10.1200/JCO.2007.13.5251; published online ahead of prin [...]

Research to improve access to quality cancer services

[...] are and the quality of treatment for colorectal cancer from diagnosis through surgery, treatment, follow‑up care, advanced disease and palliative care. Researchers will also analyze access to care for two potentially vulnerable groups: ad [...]

Gastroenterology sets standards for CT colonography

[...] s should be interpreted by the physician, according to Eurekalert, the news service of the American Association for the Advancement of Science. Despite the fact that CT colonography has not yet been endorsed as a primary screening test in asymp [...]

Rationing of cancer drugs defies ’duty of care’

[...] o colon cancer patients. In September 2005, when Avastin was approved by Health Canada, it was deemed to be the biggest advance in colon cancer therapy in years. Therefore, it became the "standard of care" for colon cancer in all G7 c [...]

Colorectal cancer screening under-used prevention tool in Canada: study

[...] ase that has no evident symptoms in the early stages. So in many cases the disease is not diagnosed until the cancer is advanced, at which point the prognosis is poor. Zarychanski and his co-authors looked at data from the 2003 Canadian Communi [...]

When was the last time you had colorectal screening?

[...] Not enough Canadians are taking advantage of colorectal cancer screening claims a recent research. The Canadian Association of Gastroenterology recommends t [...]

Screening tools that could save your life

[...] ble age range with a family history of the disease, he is regularly tested. "It's available and people should take advantage," Abbott said. "More people should make sure they follow up as well." The problem is that what a he [...]

Less Invasive Colon Surgery Results in Fewer Blood Clots: Study - US News and World Repor

[...] aid. The benefits of less invasive laparoscopic surgery also include faster recovery time and a smaller scar, but these advantages may not be enough to bring about a widespread switch from traditional surgery. "From the cancer perspective, this [...]

Sophie’s Run

[...] e to reflect on this tragedy taking place in our families' lives. Although my mom's cancer was diagnosed late and in an advanced stage — she never once gave up. She battled and fought for every day she lived with the disease. Her determin [...]

Initial Polypectomy Dramatically Reduces Colon Cancer Deaths

[...] l polypectomy rather than surveillance colonoscopy is in line with previous research demonstrating the low incidence of advanced adenomas during follow-up in participants in the National Polyp Study, she suggested. Dr. Zauber's team maintains t [...]

Fast Drop In Cancer Deaths

[...] m forming. The other gain is the result of new treatments, which are credited with doubling survival times for the most advanced patients. Overall, for men, death rates declined for 12 of the 15 most common causes of cancer: lung, prostate, col [...]

First New Class of Platinum-Based Chemotherapy Drug Candidates in 30 Years Demonstrate Ability to Kill Tumors Resistant to Currently Marketed Platinum Drugs

[...] xisting monoplatinates — especially against platinum-resistant tumors. These agents could represent a significant advance in the treatment of a wide variety of cancers." Novel bisplatinum complexes characterized by an improved in vitro pl [...]

Mayo researchers look to chromosome for clues on colon cancer

[...] ere more likely to have telomere shortening than women with the disease. Colon cancer in younger patients is often more advanced than in older patients at the time of diagnosis, the report suggested. [...]

Minority patients prefer optical colonoscopy for colorectal cancer screening

[...] stro.org. ### About the AGA Institute The American Gastroenterological Association (AGA) is dedicated to the mission of advancing the science and practice of gastroenterology. Founded in 1897, the AGA is one of the oldest medical-specialty soci [...]

Going the distance in memory of mom

[...] octor for about two years," she said. By the time Sophie saw a doctor and was diagnosed in 2005, the cancer was too far advanced. Chuchmach decided to become her mom's primary caregiver. Running became a release for her — a chance to get [...]

P.E.I. exploring feasibility of colorectal cancer screening

[...] ls between the ages of 50 to 75 for screening and developing a good awareness campaign to enlighten Islanders about the advantages of being screened. She is not in a position to say what the recommendations to government might be. “So the dec [...]

New article

[...] %, 10%). About ImClone Systems ImClone Systems Incorporated is a fully integratedbiopharmaceutical company committed to advancing oncology care bydeveloping and commercializing a portfolio of targeted biologictreatments designed to address the [...]

Bowel cancer screening halves emergency admissions, cuts deaths

[...] emergency surgery died. By 2004, this figure had fallen to just 13 percent. The number of Dukes C or stage 3 relatively advanced bowel cancers also fell from 38 in 1999 to 16 in 2004, although the proportion of these cases requiring emergency c [...]

Recent studies confirm significant underuse of colorectal cancer screening

[...] al Endoscopy Founded in 1941, the mission of the American Society for Gastrointestinal Endoscopy is to be the leader in advancing patient care and digestive health by promoting excellence in gastrointestinal endoscopy. ASGE, with more than 10,0 [...]

GeneNews initiates patient sample accrual for validation studies of colon cancer blood test

[...] inclusion in clinical validation studies of ColonSentry. These studies are expected to commence in 2008 as the Company advances its development efforts. The Company expects to initially offer ColonSentry as a reference laboratory-based test wh [...]

Sask. will get cancer screening program

[...] d," Stein said. He's pleased the provincial government confirmed Wednesday that it plans to fund Avastin for those with advanced colon cancer. Although the drug doesn't help everybody, it can impede the growth of cancer by cutting off the blood [...]

fecal test program aims to reduce colon cancer deaths

[...] e a fecal occult blood test every year. The goal is to reduce cut the growing number of patients who are diagnosed with advanced and often untreatable cancer. "This stool test picks up the cancer earlier, when there are no symptoms at all," Rab [...]

Second Surgery to Remove Cancer Spread to Liver May Improve Colorectal Cancer Survival

[...] lated deaths in the United States. The liver is one of the most common places to which colorectal cancer spreads in its advanced stages. Cancer spread to the liver is referred to as liver metastasis. Treatment for liver metastasis depends upon [...]

GeneNews publication confirms blood-based colorectal cancer biomarker results

[...] tterns of unique biomarker sets in blood," said C.C. Liew, PhD, Chief Scientist of GeneNews. "Since this study, we have advanced our technology and worked with an expanded patient population to identify additional markers specific to colon canc [...]

New Function For Colon Cancer Gene Found

[...] es to explore the molecular workings of APC in the fruit fly, a simple animal with rapid breeding time that offers many advantages in the laboratory. When they remove or reduce APC, they see fruit flies with no wings, peculiar abdomens and many [...]

Father of Breakthrough Cancer Therapy Dies

[...] rom patients for drugs that cannot be obtained. If too late, then critics say that hope was destroyed for patients with advanced disease." Antiangiogenic drugs have had mixed results in human clinical trials over the past decade, including one [...]

More cancer patients to be treated with Eloxatin(R) following Health Canada’s approval of new indication

[...] ty and efficacy profile of Eloxatin is clinically superior to the previous standard treatment, making this an important advancement in the treatment of the disease." Barry D. Stein, president of the Colorectal Cancer Association of Canada, ackn [...]

Colon cancer survivor stresses awareness of symptoms

[...] oes not always present symptoms. Colon cancer symptoms sometimes do not appear until the disease has progressed into an advanced stage. Bleeding - Blood in Stool: This is the most commonly experienced colon cancer symptom. Weight Loss: An unexp [...]

Sask to cover Avastin

[...] 3. The province will provide about $4 million to the Saskatchewan Cancer Agency for the drug used to help patients with advanced colorectal cancer. Saskatchewan resident Keith Whyte — who has actively lobbied the province to fund the drug [...]

Researchers Identify Novel Molecular Pattern Linked to Colon Cancer Prognosis

[...] at it warranted further study. Subsequently, the scientists found that miR-21 expression tracked tumor stage - the more advanced the tumor, the greater the amount of miR-21 present - indicating that it may play a role in cancer development and [...]

Patients pleased as Saskatchewan decides to fund drug for colorectal cancer

[...] they paid for it out of their own pockets. Whyte had spent more than $30,000 to get Avastin. Avastin is not a cure for advanced colon and rectal cancer. However, studies have suggested that it can be effective when used with other chemotherapy [...]

Preventing Cancer Is More Possible Than You Think

[...] alcohol at all, it should be consumed in moderation. It is somewhat paradoxical (and unfortunate) that the significant advances in medicine have enabled some people to take a rather relaxed approach to being health conscious about diet, exerci [...]

Small light probe detects colon polyps throughout entire colon by testing normal tissue in the rectum

[...] ect differences in patients who harbored adenomas when compared with those who were neoplasia free. Thus, the technical advance of LEBS may potentially translate into a practical means for colon cancer screening. With funds from the National Ca [...]

Woman wants province to foot cancer-drug cost — Avastin

[...] effects of the patient's cancer. "It's certainly not a cure," he said. "The studies have shown an approximate survival advantage of maybe three or four months for patients on Avastin, but it doesn't really cure patients unfortunately." Kumar s [...]

Critics: province should fund cancer drug

[...] Quebec, Newfoundland and Saskatchewan. When used alongside other drugs, Avastin increases survival rates for those with advanced forms of cancer and can make surgery an option for some patients, said Stein. The drug reduces the blood supply to [...]

AstraZeneca Provides Update On RECENTIN™ Clinical Development Programme

[...] 0 new cases and 492,000 deaths annually. The Horizon Study Programme is evaluating RECENTIN in patients with first line advanced colorectal cancer: RECENTIN: a potent and selective VEGF signalling inhibitor RECENTIN is a once-daily, orally avai [...]

Vanessa Williams and Carmen Marc Valvo Make It Fashionable to Talk About Colon Cancer In New Public Service Announcement

[...] pear in a new public service campaign to educate people about the importance of screening. The PSAs also note that with advances in treatment, more people are surviving colorectal cancer than ever before and highlight the potential benefit of w [...]

Cancer victims want life-extending drug made available

[...] ut prevention and screening are only half the battle," said Stein. "Having access to ... Avastin, enables patients with advanced colorectal cancer an opportunity to live longer than ever before and in some cases, when coupled with surgery, a ch [...]

Innovative treatment paid for in other provinces

[...] etween life and death. Gourd, a former deputy minister of communications for the federal government, was diagnosed with advanced colorectal cancer in March 2003. It had spread to his liver and lungs, and the resident of Gatineau was told he had [...]

Getting the okay for foreign treatment

[...] vin, he said. He had doctors file the mandatory requests with the Régie, and the family went abroad. But Kaplan was in advanced stages of leukemia and the treatment failed. She died at Hadassah Hospital three months after starting therapy. A w [...]

Fund Avastin at Cost – Wilson

[...] do for people who need this life-extending drug.” Avastin was approved by Health Canada in 2005 for the treatment of advanced colorectal cancer. It is covered in Newfoundland, Quebec, BC and Saskatchewan. Nova Scotia has the second highest m [...]

Seventh International Colorectal Cancer Congress

[...] iction and prognostication of treatment response. The goal of this congress is for participants to integrate the latest advances in the treatment of colorectal cancer into their daily practice as well as to discuss future directions in research [...]

Cancer survival rates still vary says charity

[...] al rates for lung cancer, pancreatic cancer and stomach cancers, which have hardly improved despite 40 years of medical advances. What did the report look at? The report was compiled by Macmillan Cancer Support to estimate how long people lived [...]

DiagnoCure Oncology Laboratories Introduces Previstage GCC, the First Molecular Colorectal Cancer Staging Test - Company Hires Specialty Sales Force

[...] tated John Schafer, CEO of DiagnoCure Oncology Laboratories. "Therefore, we are excited to introduce Previstage GCC, an advanced, highly specific molecular staging method which could provide clinicians with the ability to detect with molecular [...]

Diagnostic Tool Provides Additional Therapeutic Treatment Guidance For Third Deadliest Form Of Cancer

[...] s and services helping patients in nearly 90 countries, Genzyme is a leader in the effort to develop and apply the most advanced technologies in the life sciences. The company's products and services are focused on rare inherited disorders, kid [...]

Selenium to prevent recurrence of colorectal polyps

[...] e end of supplementation. In addition to seeing if patients taking selenium have a lower risk of adenoma recurrence and advanced adenomas (adenomas closer to becoming cancer), the trial will characterise any side effects observed with long-term [...]

Fruit and veg keep cancer at bay

[...] od science. It is now accepted that the diet enjoyed by those living in the Far East or the Mediterranean countries has advantages over typical Western fare and contributes to a longer life. Scientists can now explain the biochemical mechanism [...]

New Method Proposed for Determining Which Patients Should Get Treatment for Colorectal Cancer

[...] the amount of treatment that patients with thin lesions may need." * John E. Niederhuber, M.D., Director, NCI: "Simple advances in treatment that are derived by comparing national statistics to clinical data are greatly welcomed and are an exc [...]

UPDATE:Colon Cancer Study Backs Gene’s Role In Erbitux Benefit

[...] sitive for Erbitux. "A favorable KRAS wild-type benefit can appreciably push the penetration rates across all lines in [advanced colorectal cancer]," wrote King in a research note. "Further, as Erbitux use moves into earlier lines of therapy, w [...]

Amgen (AMGN) Presents Results from Two Phase 3 Trials on Vectibix(R)

[...] biotechnology company, engages in the discovery, development, manufacture, and marketing of human therapeutics based on advances in cellular and molecular biology. [...]

Study Recognizes Gene’s Role In Erbitux Benefit

[...] Cutsem. "We have shown that the activity of cetuximab is confined to the patients with the KRAS tumor so, if we know in advance that a patient has the mutation, we know that we don't have to treat them with cetuximab," he concluded. The mutatio [...]

Avastin in the Winnipeg Free Press and Introductions

[...] from six. On Jan. 4, 2004, she watched, on a screen, a scope travel through her colon. "It was very obvious that I had advanced colon cancer," she recalls. The cancer spread to Arnot's liver, then her lung. Last August, after more than three y [...]

NEW FINDING RE-OPENS BOOK ON COLON CANCER STEM CELLS

[...] According to Rafii, that may be a better way to identify the true cancer-initiating cells that actually make treating advanced and metastatic cancers so difficult. [...]

Vaccine Stops Colon Cancer’s Spread in Mice

[...] Jefferson Medical College at Thomas Jefferson University in Philadelphia. The theory behind the new vaccine is to take advantage of the immune system in the intestines where colon cancer starts, Waldman said. By targeting this immune system, a [...]

Poverty, Poor Health Might Influence Colorectal Cancer Screening Attendance

[...] in colorectal cancer screening. Annals of Behavioral Medicine 35(3), 2008. Health Behavior News Service Center for the Advancement of Health 2000 Florida Ave. NW, Ste 210 Washington, DC 20009 United States http://www.hbns.org [...]

’She’s a pistol’

[...] from six. On Jan. 4, 2004, she watched, on a screen, a scope travel through her colon. "It was very obvious that I had advanced colon cancer," she recalls. The cancer spread to Arnot's liver, then her lung. Last August, after more than three y [...]

Estrogen may protect against colorectal cancer

[...] at women aged 50 and younger were about half as likely to die from colorectal cancer as their male peers, no matter how advanced their disease was when it was diagnosed. But older women were 38 percent more likely to die of the disease than men [...]

New Weapon For Attacking Tumor Invasion And Metastasis

[...] y recurrence or distant organ metastasis. There is also a pressing need for more effective treatments for patients with advanced colorectal cancer. In the view of the authors, their research has shown elevated CXCR4 (a new receptor on cancer ce [...]

Colon Cancer 73% More Common in Men

[...] . Source: Regula Jaroslaw, Rupinski Maciej, Kraszewska Ewa "Colonoscopy in Colorectal-Cancer Screening for Detection of Advanced Neoplasia." The New England Journal of Medicine 355(2006): 1863-1872. [...]

Lack of cancer test costs Ontario millions

[...] n determined, Dr. Pritzker said funding for this type of testing is usually provided through Cancer Care Ontario. “An advance of this type has happened so quickly,” he said. “It's a challenge across the world.” Although the value of K-r [...]

Mucosa-Restricted Antigen Induces Immunologic Response to Colorectal Cancer

[...] s by about 50%, the researchers note, an immunotherapeutic efficacy comparable to other self-antigens that have already advanced from mouse models to human trials. GCC-targeted immunity appeared to be mediated by CD8+ T cells and not by CD4+ T [...]

Expensive drug to treat colorectal cancer will only be covered for patients whose doctors recommend it as part of their first therapy

[...] er than affecting all the cells in the body, has been shown to be most effective when used as the initial treatment for advanced colorectal cancer. The province will pick up the tab for up to eight months of treatment for patients whose doctors [...]

Bush’s ex-spokesman Tony Snow dies of colon cancer

[...] other died from the disease at the age of 38 when he was 17. Thirty-seven years later with cancer treatments “greatly advanced”, snow died of the same disease. Colon cancer occurs in the tissue of the colon, the longest part of the large in [...]

Lower Risk Of Cancer Recurrence In Patients With Family History Of Colorectal Cancer

[...] Among patients with advanced colon cancer receiving treatment that includes chemotherapy, a family history of colorectal cancer is associated wi [...]

Laparoscopic Surgery Reported More Effective than Open Surgery for Colon Cancer

[...] July 2008 edition of the Annals of Surgery.1 Laparoscopic surgery is used for many types of surgery with the short term advantages of less pain, fewer wound complications, quicker post-operative recovery, and shorter hospital stays. However, th [...]

Preventing Colorectal Cancer Through A Healthy Lifestyle

[...] d weight management and their effect on risk for 17 types of cancer, one being colorectal, the following conclusion was advanced in respect of body weight: “Maintain a normal weight and keep your bmi between 18.5 and 25 in order to avoid deve [...]

Exercise Lowers Risk of Colon Cancer

[...] colon cancer prevention is not as well publicized as it could be," Coups said in a new release from the Center for the Advancement of Health. Doctors may find it easier to tell patients about the general health benefits of exercise, rather tha [...]

Growth Inhibition of Human Colon Cancer Cells By Plant Compounds

[...] s well as information on important clinical laboratory-related topics such as technological, clinical, and experimental advances and innovations. Literature reviews are also included. Direct all inquiries to David L McGlasson MS CLS(NCA), 59th [...]

Crucial genetic factor in colorectal cancer found

[...] testine, the researchers said. If caught early, colorectal cancer often can be cured but is usually fatal if it becomes advanced. Pasche said a blood test for the trait could be available perhaps within a couple of years. "People with known ris [...]

Nova Scotia Confirms Commitment to Fund Avastin

[...] ent of Nova Scotia for honouring its promise to fund Avastin (bevacizumab), an important medication in the treatment of advanced colorectal cancer. "We are thrilled that the government of Nova Scotia has followed through on its commitment to pr [...]

Exercise Lowers Risk of Colon Cancer

[...] colon cancer prevention is not as well publicized as it could be," Coups said in a new release from the Center for the Advancement of Health. Doctors may find it easier to tell patients about the general health benefits of exercise, rather tha [...]

Marshall Gets $1.3 Million in Rural Health Funding

[...] ical and professional skills necessary to establish a regional “Virtual Colonoscopy” program to deploy this rapidly advancing “gold standard” of cancer screening and care throughout the region. The Center will collaborate with the profe [...]

Vitamin E Is Anti-Cancer

[...] Despite great advances in medicine, cancer is still a very common disease. At current rates, more than a third of us will suffer from canc [...]

Too much folic acid may trigger cancer

[...] might actually make their condition worse." Other experts, though, argue that fortifying food offers well-proven health advantages, while evidence of any cancer risk is inconclusive at best. In fact, the Society of Obstetricians and Gynecologis [...]

Early Skin Treatment Reduces Skin Reactions in Colorectal Cancer Patients Treated with VectibixÂ

[...] imed at minimizing skin reactions associated with treatment with Vectibix. This trial included nearly 100 patients with advanced, recurrent colorectal cancer who were treated with Vectibix plus a Camptosar® (irinotecan)-based chemotherapy re [...]

Screening for colorectal cancer recurrence falls short: study

[...] said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society, which funded the study. Despite advanced medical technology, "our ability to deliver the recommended care to patients has left something to be desired." [...]

Avastin may increase risk of neural bleeding and stroke in patients with glioblastoma multiforme, physicians say

[...] ble treatments for patients with metastatic glioblastoma, if Avastin is shown to be an efficacious, it would be a major advantage for this patient population, said Dr Chin Wang, an oncologist at the Cancer Institute of Dallas. Wang agreed that [...]

Gene causing colon cancer identified

[...] lained Hahn, who is also an associate professor of medicine at Harvard Medical School The findings were published in an advanced online edition of Nature Sunday . [...]

Colorectal Cancer: Multimodality Management

[...] many new possibilities for managing colorectal cancer. Here the practicing clinician will find cutting-edge reviews on advances in diagnostic and therapeutic radiology and the surgical aspects of treating colorectal cancer. More Information [...]

New DNA Stool Testing Spots More Colon Cancers

[...] s, they suggested that the newer and apparently more sensitive DNA stool screening method could represent a substantial advance in molecular screening technology. And although colonoscopy screening is still the more effective option to date, th [...]

Older Medicaid Patients Less Likely to Be Screened for Certain Cancers

[...] and claims data were analyzed together. Previous studies have shown that Medicaid recipients are more likely to have an advanced stage of cancer at the time of diagnosis than patients with other sources of health insurance, the researchers said [...]

Health Canada approves "Personalized medicine" for metastatic colorectal cancer

[...] re most likely to benefit from Vectibix(TM), while those who are not can be redirected to other treatment options. This advance brings us one step closer to personalized medicine in oncology," said Dr. Thierry Alcindor, assistant professor of M [...]

Blood test for colon cancer on the horizon

[...] ker for colorectal cancer. CCSA-2 not only detects the presence of colorectal cancer but may also differentiate between advanced and nonadvanced adenomas. The ultimate goal is to combine the biomarkers, five identified so far, into a serum assa [...]

New Insight into Colorectal Cancer Drug

[...] as we progress toward fully understanding the role of K-ras as a predictive biomarker in the treatment of patients with advanced colon cancer,” Christos Karapetis, M.D., the study’s lead investigator from Flinders Medical Centre and Flinder [...]

Tests Could Predict Benefit From Cancer Drugs

[...] ials involving 715 patients. They confirmed that the cancer drug Vectibix (panitumumab) was only successful in treating advanced colorectal cancer in patients with the normal ("wild type") form of the KRAS gene — not a mutated version. Ve [...]

Bevacizumab Better Than Gold Standard Imaging At Detecting Tumors

[...] ss by which a growing tumour creates its own blood supply). Currently, bevacizumab is being used to treat patients with advanced colorectal cancer and is being tested in several other metastatic cancers. When the researchers injected the compou [...]

No lucky surprise on Genentech drug

[...] ue package not for automakers 11.12.08 * Holcim 3Q profits down, plans to shut 2 US plants 11.12.08 Experts who took an advance peek at the Avastin data found no reason to stop the trial early, an action often taken when an experimental treatme [...]

Don’t let colon cancer outsmart you - get tested

[...] een linked to colon cancer. Are there any symptoms of the disease? Most symptoms aren't noticeable until the disease is advanced. For instance, you may notice bright red blood in the stool or cramping pain in your abdomen that doesn't subside, [...]

Gut wrenching

[...] better do a colonoscopy,’ ” Stein says. “To everybody’s surprise, not only did I have colon cancer, but it was advanced to the point where they gave me a 30 per cent chance of surviving the next five years.” That was over a decade ag [...]

Millions could benefit from Colon Cancer Screening

[...] time to be screened for colon cancer and many other cancers. “By the time the warning signs occur, the cancer may be advanced,” he says. “If the cancers are detected when they’re feeling healthy, they’re almost always curable.” Tho [...]

Clarient Introduces Second Gene Mutation Test for Colorectal Cancer

[...] r testing. Clarient is that resource, having created a state-of-the-art commercial cancer laboratory providing the most advanced oncology testing and drug development services available both onsite and over the web. Clarient is a Safeguard Scie [...]

Mind the gap

[...] t have to focus better. They need to find their target population and figure out what works best. They need to use more advanced technology to hone in on those groups.” [...]

Exiqon Announces Launch of First Molecular Diagnostic Test for Colon Cancer

[...] qon is a biotech company with activities in three business areas where the company's technologies provide a competitive advantage: Sale of diagnostic tests (Exiqon Diagnostics), sale of innovative research products for miRNA research (Exiqon Li [...]

Research Improves Accuracy Of Colorectal Cancer Staging

[...] highly sensitive detection methods to specimens from early stage colorectal cancer patients, and evaluate whether these advanced methods could help predict which patients are likeliest to recur, so that they could receive more aggressive therap [...]

Public gives £1m to cancer research

[...] eive a £1m boost. Cancer Research Wales will distribute the money, which was raised by the public in the past year, to advanced research projects into cancer across North, South and West Wales. The money will benefit research into a range of c [...]

New guidelines on nutrition, calcium, and colon cancer

[...] f calcium supplements, and new guidelines in the detection of colon cancer. These new developments represent the latest advances in nutrition, osteoporosis treatment, and colorectal cancer screening. New Food Guidelines For Older Adults The foo [...]

Sask. spends $1.1M on new cancer test

[...] help save lives," McHattie said. "It's going to reduce pain and suffering and reduce the personal and economic cost of advanced colorectal cancer. Only about 20 per cent of people between the ages of 50 and 74 are screened for colorectal cance [...]

New article

[...] es the risk of oral, throat, pancreatic, uterine, bladder, and kidney cancers. "Even though there have been many recent advances in lung cancer treatments, the most effective way to eradicate lung cancer is to prevent it from ever happening," e [...]

ASCO Releases Provisional Clinical Opinio

[...] Alexandria, Va. - In advance of the sixth annual Gastrointestinal Cancers Symposium (January 15-17 in San Francisco, CA), the American Society of [...]

African-Americans Have Worse Prognosis At Colorectal Cancer Diagnosis

[...] cation, stage and histologic grade of the cancer. In both patient groups, more African-American patients presented with advanced disease (defined as stage III or stage IV) at diagnosis. African-American patients were also more likely to have pr [...]

Colon Cancer Study Involving Avastin Expected By April

[...] ts who have had surgery, could be released as early as April. Avastin is currently approved to treatment metastatic and advanced colorectal cancer. The 2,710-patient study, known as NSABP, is designed to show it can delay disease progression in [...]

Taking aspirin daily may cut one’s chances of developing the polyps that can lead to colorectal cancer

[...] daily aspirin prevented recurrence of these polyps. The people who took aspirin were 28 percent less likely to develop advanced adenomas than those taking a placebo and 17 percent less likely to develop any adenoma. "If we can find a way to pr [...]

Alberta may refuse to pay for life-prolonging drug

[...] mments follow the Alberta Cancer Board's Jan. 15 decision to recommend the government fund Avastin for the treatment of advanced colon cancer. The board recommended public coverage for the therapy after reviewing studies that show Avastin, admi [...]

Experts: We’re in Vitamin D Deficiency Crisis

[...] tamin D Deficiency Month.” Between 2004 and 2007, the foundation gave Holick, who has written a book called “The UV Advantage,” $188,904 to help finance his research. Though Holick does not advocate tanning, and is “very aware and conce [...]

Coriolus Versicolor is Potent Mushroom for Fighting Cancer and Autoimmune Diseases

[...] le help for colon cancer patients, Coriolus showed a remarkable enhancement of the patient's white blood cells, even in advanced colon cancer cases. The white cells greatly increased natural chemotactic motion and phagocytosis, the ability to s [...]

New guidelines on nutrition, calcium, and colon cancer

[...] f calcium supplements, and new guidelines in the detection of colon cancer. These new developments represent the latest advances in nutrition, osteoporosis treatment, and colorectal cancer screening. New Food Guidelines For Older Adults The foo [...]

Give cancer patients their health records: report

[...] Many Canadians living with cancer have yet to benefit from advances in technology such as electronic health records, according to a report released Tuesday. The Cancer Advocacy Coalit [...]

The Importance of Screening for Colorectal Cancer

[...] t these alternatives. Tests such as STD-II should not only become available soon but also improve as medical technology advances. Article funded through the Asian Health Initiative of Tufts Medical Center.. Comments? Questions? Please submit he [...]

Major study on DiagnoCure’s GCC biomarker published in Jama

[...] de strong evidence that GCC matters when it comes to predicting the risk of colorectal cancer recurrence and is a major advance for the individualized treatment of colorectal cancer patients. With our very sensitive GCC-based test, physicians a [...]

Alberta government adds cancer drug Avastin to its coverage list

[...] rta Health and Wellness about $4 million to $5 million each year starting April 1 as the drug is given to people in the advanced stage of colon cancer. Avastin shrinks tumours by cutting off the blood supply, but doesn’t work in all patients [...]

Colon Screening: 5 Things You Need to Know

[...] t earlier.) That doesn't mean you must get a colonoscopy (more later on alternatives), but that procedure does have the advantage of being able to identify and remove precancerous polyps. It's considered the gold standard of colorectal cancer s [...]

People who exercise lower their risk of colon cancer

[...] more than 24,000, fewer cases of colon cancer would occur each year. Wolin's report was published Feb. 10, 2009 through advance online publication in the British Journal of Cancer. In the study, she and her colleagues gathered the results from [...]

’Not to sound Neanderthal’: But men really don’t like going to the doctor

[...] " said Dewan, a gastroenterologist with Michigan State University/Kalamazoo Center for Medical Studies. All the medical advances in the world cannot save a patient who simply doesn't go to the doctor. And many men don't go to the doctor unless [...]

Doc rues shyness in fight against bowel cancer

[...] checks in general. “I think that we actually can screen for colon cancer well, and I think that everybody should take advantage of it... It’s a simple test of your stool to look for microscopic blood. Patients can do it on their own, at hom [...]

The Medical Minute: Laparoscopic colorectal surgery

[...] this removal of the colon and its lymph nodes that provide a stage for the patient’s cancer, telling the surgeon how advanced the cancer may be. Laparoscopic surgery for colorectal cancer follows the same principles as open surgery. The amou [...]

Ottawa Half Marathon

[...] he several years of our friendship, I witnessed his suffering and felt impotent. This is why I have decided now to take advantage of my health for the sake of those who do not have the same good fortune. Inspired and encouraged by my almost-wee [...]

Fatty oil in fish may help reduce tumors: study

[...] a 3 fatty acids — the kind found in fish such as salmon, mackerel, herring and sardines — protected against advanced prostate cancer even in men more at risk of the disease. The fatty acids, also found in foods such as walnuts and l [...]

Found: a c-word for cancer

[...] te, 91 per cent. But these numbers do not distinguish between those who will die of cancer and those who will not. With advances in early detection, treatment and care, patients don't merely survive cancer any more - they can be cured. Yet many [...]

Colon Cancer Progression Benefit Confirmed

[...] group was 9.9 months with combination therapy and 8.7 months with chemotherapy alone. In contrast, cetuximab offered no advantage in patients with kras mutations, reflected in a median progression-free survival of 7.6 months versus 8.1 months i [...]

Folic Acid Fortification May Be Linked to Increased Colon Cancer Risk

[...] hes papers reporting original clinical and scientific research which are of a high standard and which contribute to the advancement of knowledge in the field of gastroenterology and hepatology. Visit the journal website at http://www.eurojgh.co [...]

Age cutoffs for colon cancer screening debated

[...] without significant conditions, for whom guidelines do recommend screening. Colorectal cancer screening decreased with advancing age, the team reports in the Annals of Internal Medicine. However, rates of screening did not fall below 30 percen [...]

Avastin Trial May Dent Confidence In Key Growth Area For Drug

[...] es a royalty from Avastin sales. Shares of the company recently dropped 5% to $6.98. Avastin, already approved to treat advanced breast, lung and colorectal cancer, had 2008 U.S. sales of $2.69 billion. Despite the failure, Avastin's use in the [...]

Survivor stories

[...] cancer strikes both men and women equally. • It is a silent killer. Often, there are no symptoms until it reaches an advanced stage. That is exactly why early detection is so important. Those at increased risk include: — People age 50 year [...]

Cancer Prevention: Diet, Lifestyle and Beyond

[...] event and cure cancer. Founded in 1907, AACR is the world’s oldest and largest professional organization dedicated to advancing cancer research. The membership includes more than 28,000 basic, translational and clinical researchers; health ca [...]

Avastin® Fails to Provide Benefit in Early-stage Colon Cancer

[...] udy) are expected to be available in 2010. Comments: These results of these studies do not affect the use of Avastin in advanced colon cancer. It will be of interest to see the details of the two studies of adjuvant Avastin in colorectal cancer [...]

Ulcerative Colitis and Cancer

[...] angitis. Ann Intern Med. 2001;134(2):89-95. 21. Wong NA, Harrison DJ. Colorectal neoplasia in ulcerative colitis-recent advances. Histopathology. 2001;39(3):221-234. 22. Khosraviani K, Weir HP, Hamilton P, Moorehead J, Williamson K. Effect of f [...]

Les graisses trans augmentent le risque de cancer du côlon

[...] S. SandlerConsumption of trans-Fatty Acid and Its Association with Colorectal Adenomas American Journal of Epidemiology Advance Access published on June 27, 2008 Am. J. Epidemiol. [...]

At Cold Spring Harbor Meeting, Next-Gen Sequencing Dominates Cancer Talks

[...] program" involving the Applied Biosystems SOLiD system, whose longer-insert mate pairs and higher read density could be advantageous for certain analyses, for example of copy number variants, he said. One challenge for accurately determining so [...]

Provincial government cap on drug upsets cancer patients

[...] the cells in the body. Clinical trials have shown that Avastin is most effective when used as the initial treatment for advanced colorectal cancer, stated the ministry. A health ministry spokesperson has said 12 Avastin cycles are the base trea [...]

The pros and cons of virtual colonoscopy

[...] ey fear pain or injury, can't afford to pay for the test, don't think they need the test, or don't know about the test. Advantages of virtual colonoscopy • No sedative is required. • No scope is thread through the colon, so procedure is les [...]

Addition of Eloxatin® to Adjuvant Chemotherapy Improves Colon Cancer Outcomes

[...] in patients with Stage II colon cancer has not yet been firmly established. Stage III colon cancer is considered a more advanced cancer than Stage II colon cancer. It refers to cancer that has spread to local lymph nodes but not to distant part [...]

Cancer Drug Erases Man’s Fingerprints

[...] nter, says his patient, identified as "Mr. S," had been taking the drug Xeloda since July 2005 to prevent recurrence of advanced cancer that had responded well to chemotherapy. The cancer patient was detained by U.S. Customs officials for four [...]

Roche’s Avastin Fails in Early Colon Cancer

[...] er similar treatments, and it bodes poorly for other early-stage trials of Avastin. The drug, already approved to treat advanced breast, lung, brain and colorectal cancer, had 2008 U.S. sales of $2.69 billion. The study played an important role [...]

Quebec to screen for colorectal cancer

[...] e-wide screening program would cost $18 million to $30 million a year, but the costs would probably drop as a result of advances in mechanization and other technical improvements. Stein, a colorectal cancer survivor, predicted a screening progr [...]

Colon Cancer Screening Technique Shows Continued Promise In New Study

[...] one can detect these changes earlier than we can." The study examined tissue from 219 patients. Results showed that for advanced polyps, the test had a sensitivity of 100 percent, which means that 100 percent of patients who had polyps were cor [...]

MEDICARE: Colonoscopies and Evidence-Based Decision Making | New America Blogs

[...] last month to deny coverage for Computed Tomographic (CT) Colonography. CT Colonography, or "virtual colonoscopy," uses advanced imaging technology to look for precancerous polyps. Some patients prefer it; it is quicker, doesn't involve anesthe [...]

How Close Avastin Really Came To Adjuvant Colorectal Cancer Use

[...] oincidentally, the time period that patients received bevacizumab), there was a significant benefit for the drug. A 40% advantage, to be precise. Lots of zeroes in the p-value to make the statisticians happy. More than enough benefit to drive u [...]

Un essai contrôlé randomisé de microsphères de résine radioactives démontre une prolongation importante de la progression de la

[...] 2 trial of SIR-Spheres plus fluorouracil/ leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer. Journal of Surgical Oncology 2004; 88 : 78-85. [6] FOLFOX plus SIR-Spheres microspheres versus F [...]

The cost of fighting cancer

[...] of Health began funding Avastin last July through the Ontario Public Drug program. It is specifically funded for use in advanced colorectal cancer and has been proven to improve survival by five months. Ministry spokesperson Andrew Morrison sai [...]

College of Medicine pioneers new cancer treatment

[...] k, founding dean and senior vice president for medical affairs for the College of Medicine. “That makes Dr. Gulec’s advancements in the field of radiomicrosphere therapy an incredibly important step forward in cancer research.” The therap [...]

New Promising, Early Diagnostic Options for Colon Cancer

[...] agnostic techniques have the potential to save millions of lives, as colon cancer is often not caught until it’s well advanced. Lead researcher Sefi Vernick, a doctoral student of the Department of Physical Electronics at Tel Aviv University, [...]

Study Finds Possible Genetic Indicator of Colorectal Cancer

[...] s say they may be moving closer to developing a genetic test for colorectal cancer that could indicate who needs a more advanced colonoscopy screening. In a study released this week, an international team of researchers report that they've foun [...]

Colon Scan May Be ’Appealing Solution’ to Find High-Risk Cancer

[...] who have a high risk of colon cancer, researchers said. The computed tomography, or CT, scans identified 85 percent of advanced abnormal-growth spots and colorectal cancers in the Italian study, and correctly ruled them out in 88 percent of ca [...]

Ontario’s Ombudsman agrees to investigate cap on Avastin treatment

[...] roundbreaking drug”. Clinical trials have shown that Avastin is most effective when used as the initial treatment for advanced colorectal cancer, stated the ministry. A person is funded for 12 base treatments and can get up to four more if a [...]

Study: Weight-loss surgery cuts cancer risk in women

[...] by Dr. Andrew G. Renehan of the University of Manchester, in the United Kingdom. Therefore, a longer study may show an advantage for men. "I think the message here is that obesity increases the risk of cancer, [so] more aggressive screening fo [...]

Variation In Polyp Detection Rates At Screening Colonoscopy

[...] , it can be removed immediately. The polyp is usually removed with small biopsy forceps or loop of wire (snare) that is advanced within a channel in the colonoscope. Studies of screening colonoscopy have documented variation in adenoma (benign [...]

Study finds improved communication encourages patients to seek colorectal cancer screening

[...] identified this year, and more than 52,000 people would die from colon and rectal cancer. Most cases are detected at an advanced stage, when the chances the patient can recover decrease. The National Cancer Institute estimates that the five-yea [...]

The Associated Press: Pfizer discontinues Sutent colon cancer study

[...] tent) as an initial treatment for colon cancer because the drug is not proving effective enough. Sutent is approved for advanced kidney cancer and gastrointestinal cancer. The clinical trial compared the drug in combination with a type of chemo [...]

Factors associated with improved survival among older colorectal cancer patients in the US: a population-based analysis

[...] for the largest share of the change in 5-year survival in CC and RC between 1992 and 2000. Conclusions: : Technological advances and changes in patient demographics had the largest impact on improved colorectal cancer survival during the study [...]

Racial gap in colon cancer diagnosis, treatment

[...] t more likely to die within five years than white patients were. In general, African Americans were more likely to have advanced cancer at diagnosis; nearly 48 percent were diagnosed with stage III or IV cancer — where the tumor has sprea [...]

Cell Pathway May Be Key to Lung Cancer’s Spread

[...] cancer. When caught early, lung cancer can often be treated. But most cases are not detected until the disease is well advanced. Though doctors can sometimes put the cancer into remission, the disease often springs back more virulent than ever [...]

“Virtual colonoscopy” may be an option, study shows

[...] ople, giving each both a real and virtual colonoscopy on the same day. The x-rays found 151 of the 177 patients who had advanced neoplasia — the lesions most likely to become tumors if not removed. “CT colonography detected 39 of 41 par [...]

Genetic Testing May Be Valuable In Treating Colorectal Cancer

[...] and Chairman of the Weill Cornell Department of Public Health. "Both methods are becoming increasingly integral to the advancement of evidence-based medicine." Additional co-authors include Drs. Michael J. Hall of Fox Chase Cancer Center in Ph [...]

Moving to the US increases cancer risk for Hispanics

[...] prevent and cure cancer. Founded in 1907, AACR is the world's oldest and largest professional organization dedicated to advancing cancer research. The membership includes more than 28,000 basic, translational and clinical researchers; health ca [...]

Amgen’s Personalized Strategy for Cancer Pays Off in Big Colon Cancer Trial

[...] othesis that KRAS was important for Vectibix, it modified the design of the 1,100 patient trial to ask that question in advance—whether the drug really works better for normal KRAS patients. That’s more like stepping behind the line, declar [...]

DIET DOCS: With colon cancer, early detection is vital

[...] eeding that was ignored for months or years with devastating consequences. People mistakenly assume that they will have advanced symptoms that will "warn" them when they have colon cancer. Nothing could be further from the truth. The lower inte [...]

Attacking colon cancer with two weapons

[...] patient can't eat, then you might operate on them for that respect," says surgical oncologist Dr. Perry Shen. But this advanced cancer isn't always a lost cause, at least according to Dr. Shen. His team attacks it with two weapons - surgery an [...]

CBS NEWS - Aspirin: New Weapon in Colon Cancer Fight?

[...] s whose cancer had not yet spread. So future research will likely try to determine if Aspirin can help people with more advanced disease. Asked if this means everyone with colon cancer should start taking an Aspirin a day, Ashton explained that [...]

Hospira’s Generic Cancer Drug Delayed By Sanofi Challenge

[...] sues regarding the drug's safety or effectiveness. The drug is a treatment for patients with stage III colon cancer and advanced colorectal cancer. By Jon Kamp, Dow Jones Newswires; 617-654-6728; jon.kamp@dowjones.com [...]

Teva Pharmaceutical Industries Ltd, TEVA - oxaliplatin injection has launched by Teva

[...] ment of stage III colon cancer in patients who have undergone complete resection of the primary tumour and treatment of advanced colorectal cancer. StockEinstein.com has a dedicated team uncovering stocks ready to break and run. We apply time t [...]

Amgen says Vectibix met goal in colon cancer study

[...] with Vectibix had greater progression-free survival, a measurement of how long they lived until their disease began to advance or spread again. The study tested Vectibix as a primary, or first-line, treatment for the disease. Currently it is o [...]

Moving to the center of gravity: Biomarkers

[...] out, some 85% of colon-cancer cases are asymptomatic or involve no family history of the disease. The test has reached advanced stages of development and has been tested on hundreds of people. The results, as reported, are impressive. The kit [...]

Everyday Health Choices Keep Cancer at Bay

[...] sk. Rating the risks A process called meta-analysis was used to combine and analyze data from 103 previous studies. The advantage of this approach is that it allows for large numbers of people to be studied together. The more people in a study, [...]

Does Aspirin Help Treat Colorectal Cancer?

[...] less of whether they were stage I, II, or III at diagnosis. This study did not look at aspirin's effects in people with advanced colorectal cancer. More research in that area is needed. It also didn't address the preventive effects of regular a [...]

Too Few Latinos Get Colorectal Cancer Tests

[...] amp; Disease. While national statistics show that Latinos tend to be diagnosed with colorectal cancer during its later, advanced stages and thus have a lower survival rate than non-Latino whites, at least one doctor believes cultural issues may [...]

Cancer screens less likely for lower-income earners: StatsCan

[...] ecreased, as more women have been getting mammograms, he added. Both De and Schwartz stressed all Canadians should take advantage of the cancer-screening tests that exist. "Colorectal cancer doesn't discriminate by age, location, socioeconomic [...]

Regular aspirin use reduces risk of dying from colorectal cancer

[...] of the Journal of the American Medical Association, the study's authors also find that the aspirin-associated survival advantage was seen primarily in patients with tumors expressing the COX-2 enzyme, a characteristic of two-thirds of colorect [...]

Colorectal cancer and evidence for cure by adjuvant chemotherapy

[...] d by the ACCENT group, a novel alternative graphical presentation of the data was used to determine whether the initial advantage of adjuvant chemotherapy was maintained over time; to evaluate the time course of treatment failure; and to examin [...]

Obama Speech Heralds Prevention Power of Screening Tests Like Colonoscopy

[...] nts who should be tested, are not being screened appropriately. Recent studies reveal that they are diagnosed with more advanced cancers compared to patients with private insurance. "We can point to impressive milestones indicating a trend movi [...]

Andre Picard’s Article September 10 2009

[...] reatment costs $15,572 and the drug extends survival by 10 days. Sorafenib (Nexavar) is used to treat kidney cancer and advanced skin cancer. A course of treatment costs $34,373 and it extends survival by 2.7 months. These figures are, in thems [...]

Vectibix(R) in Combination With Chemotherapy Significantly Improves Progression-Free Survival in Second-Line Metastatic Colorectal Cancer

[...] tis, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people's lives. To learn more about our pioneering science and our vital medicines [...]

Cancer drug Erbitux extends life in one study

[...] than Vectibix. Amgen hopes to redress this imbalance by showing its drug is similarly effective, while offering dosing advantages. Both drugs have recently been found to work only in the 60 to 65 percent of patients whose tumours contain wild- [...]

Vitamin D and cancer survival

[...] d on a mathematical model developed and tested in men who did not have cancer. The fact that the model was tested is an advantage, but it is possible that the model may not work as well in women or in people with cancer. The researchers did not [...]

Redefining colorectal cancer treatment

[...] s that cancer is a complex field, even for other doctors or specialists in other fields, so it's difficult to grasp the advances in the last few years. 'And among specialties, oncology is one of the specialties growing by leaps and bounds. Ther [...]

Press Release - Statement by Ontario Ombudsman André Marin on Avastin funding

[...] the recommendation that Avastin be used together with other chemotherapy for the first-line treatment of patients with advanced colorectal cancer until progression of the disease. The guidelines do not suggest that a cap be placed on treatment [...]

Leading-edge genomic research: $2.3 M awarded to two Quebec teams

[...] hers, as well as to establish partnerships necessary for the development of Quebec's research and innovation system and advance the research internationally. The FRSQ supports the activities of 11 groups, 19 centres and 18 thematic research net [...]

Orphan Drug designation for NGR-hTNF in liver cancer

[...] arcinomas can be removed completely using surgery. If the cancer cannot be completely removed, the untreated disease in advanced stage is usually associated to a median survival time of about 6 months. About NGR-hTNF NGR-hTNF is a vascular targ [...]

Cancer leaves local couple in the cold - Journal Advocate

[...] hought was a fistula, Danny was diagnosed with stage III colorectal cancer. “And he is a veteran, and just never took advantage of the opportunity to have a colonoscopy,” Mary said. “Dumbest thing I ever didn’t do (have the test),” Da [...]

Doctors call Nunavut’s alarming smoking rates ’a health crisis’

[...] disease, once virtually unknown among Inuit, is now widespread, said Williams, who blames junk food and smoking for its advance. "Coronary disease is striking these people more aggressively and at a more premature age - at least a decade sooner [...]

Seniors face conflicting advice on cancer tests — chicagotribune.com

[...] sociated with screening procedures or therapies, and medical expenses. Take colon cancer. Although detecting a polyp is advantageous at age 50, the benefits are less clear at 80. Typically, polyps take 10 to 15 years to become cancerous and pot [...]

Colon Cancer Screening: A workplace rationale - Working Well Magazine (June/July 2009)

[...] s received colonoscopy referral forms to take to their doctors in order to be referred to reputable clinics reviewed in advance by Dr. Sotto. These clinics had to be easily accessible and provide a quality colonoscopy in a timely fashion. Looki [...]

Study: Colorectal cancer testing may become more affordable

[...] cer Society, colorectal cancer will kill an estimated 49,920 people in the U.S. each year. However, early detection and advanced testing methods may prevent deaths by allowing doctors to remove pre-cancerous polyps. ADNFCR-2248-ID-19455884-ADNF [...]

South Carolina Cancer Advocacy Community promotes continued funding for Colonoscopy Program

[...] uraging our lawmakers to continue funding for SCOPE/SC and to partner with the SCCA to ensure that more people can take advantage of this life-saving procedure.” SCOPE/SC was developed as a collaboration of the South Carolina Cancer Alliance [...]

Better health, take charge: Protect GI system to help avoid colorectal cancer

[...] n opportunities. People who have lost health insurance may be showing up later with bleeding and pain — a sign of advanced and harder-to-treat GI problems. Colon and rectum cancer spending accounts for about 13 percent of all cancer treat [...]

channelnewsasia.com - MOH to roll out colorectal cancer screening for those over 50

[...] w Zealand and the US. One major reason is that 60 per cent of our colorectal cancers are picked up too late and at more advanced stages, leading to poor survival," said Mr Khaw. [...]

Colon cancer deaths could make big drop - Cancer- msnbc.com

[...] est within the last year. “It seems to me that it’s a cascade of things that include medical science and technology advances,” said Dr. Michael Fisch, head of general oncology at the University of Texas M. D. Anderson Cancer Center in Hou [...]

Company wants to ease colon cancer detection

[...] ines to have a screening colonoscopy every 10 years, and as a result, cancer often is found only when it has reached an advanced stage, he said. The DNA test could get people who avoid colonoscopies in for help before it's too late. "It's not m [...]

NCI Cancer Bulletin for December 15, 2009 - National Cancer Institute

[...] hers assessed data on use of, and disease-free survival rates associated with, four chemotherapy regimens used to treat advanced colorectal cancer during different historical time periods. Just increasing conventional colorectal cancer treatmen [...]

Moderate exercise boosts survival rates for colorectal cancer patients

[...] e men engaged in a variety of different recreational exercises. The benefit of exercise was seen regardless of age, how advanced the cancer, weight and any history of previous physical activity. The findings are published in Archives of Interna [...]

Aspirin Wards Off Colorectal Cancer Death

[...] patients. Mayo Clinic oncologist Axel Grothey, MD, discussed these developments in an article published in Therapeutic Advances in Medical Oncology (2009;1:55). “Biomarker-based treatment decisions are…now an integral part of clinical prac [...]

Business Week- The ’Pill’ Offers Benefits Beyond Birth Control

[...] treatment of bleeding because of uterine fibroids. "We've known for many years that hormonal contraceptives have health advantages beyond preventing pregnancy," Dr. Robert L. Reid, who led the development of the bulletin, said in a news release [...]

Understanding the Genetics of Colon Cancer

[...] ool in clinical practice. One example is the development of stool DNA tests for early detection of colorectal cancer or advanced adenomas. Stool DNA testing for colorectal cancer has now been added to the cancer-screening guidelines of the Amer [...]

Colorectal Operations Associated with Death of Elderly

[...] ound that a possible solution is to delay operative care. Since the procedures that lead to death often involve locally advanced colorectal cancer, the authors also suggest that colorectal cancer screening needs to improve. [...]

New Abbott Gene-Based Test for Colorectal Cancer Receives CE Mark | SYS-CON CANADA

[...] ificantly increase the number of people being screened. "A blood test for colorectal cancer is a significant diagnostic advance that will increase compliance with screening and help physicians diagnose more patients at early stages when the dis [...]

BBC News - Poor ’more likely to have late cancer diagnosis’

[...] high, these are very striking figures and it's not improving over time. "It's tragic that it's older people and more disadvantaged people and women who are missing out on this gold standard care and we really need to look at what is going on he [...]

National Post - Colorectal cancer preventable, treatable and beatable!

[...] for equal and timely access to effective treatments across the nation. While forming the standard of care therapies for advanced disease in many other countries, provincial governments in Canada have been debating the coverage of life-prolongin [...]

Screening for colon cancer ensures best outcome

[...] ding. With cancer caught early, surgery to remove the cancerous portion of the colon may be all that is needed. In more advanced cases, chemotherapy also might be needed. Dr. Diana Yu is the Health Officer for Thurston and Mason counties. Conta [...]

Many Older Colorectal Cancer Patients Do Not Receive Adjuvant Chemotherapy

[...] About 75 to 80 percent of patients with Hodgkin lymphoma are cured by their initial treatments, but the others relapse. Advances in treatment have stagnated for 20 years because researchers have lacked markers for predicting the response to the [...]

CANCER AND IMPORTANT MEDICAL NEWS: BRAF TESTING AND MSI TESTING FOR COLORECTAL CANCER THERAPY

[...] ich metastatic colon cancer patients are candidates for anti-EGFR treatment. "If a patient has mutant KRAS, there is no advantage with the treatment," said Dr. Engstrom, adding that BRAF status is not needed when KRAS is mutated. BRAF testing s [...]

Eat fish to prevent bowel cancer—study | TheMedGuru

[...] erring. Consumption of Omega-3 fatty acids is as effective as medical drugs prescribed for the treatment, with an added advantage of no side effects associated with it, revealed the study. Details of the study The study looked at 55 patients wi [...]

Improve screening for genetic colon cancer: N.L. doctor Read more: http://www.cbc.ca/canada/newfoundland-labrador/story/2010/03/25/nl-colon-screening-325.html#ixzz0kG9Ev5Dk

[...] colonoscopy. Three times in 2008, his requests for a colonoscopy were turned down. The next year, he was diagnosed with advanced colon cancer. "I had surgery; I had three feet of my large colon taken out," said Gould, 54. "If I had been checked [...]

Empowering guts

[...] ho is also a consultant medical oncologist, “FIT has been shown in recent studies to have superior detection rates of advanced colonic lesions compared with the older guaiac-based faecal occult blood test, with greater simplicity of sample co [...]

Amgen Highlights Biomarker and Preclinical Data to be Presented at American Association for Cancer Research (AACR) Annual Meeting

[...] oncology in preclinical through Phase 3 clinical trials. "The data presented at AACR highlight the important scientific advances that are being made in cancer research," said Roger M. Perlmutter, M.D., Ph.D., executive vice president of Researc [...]

Failure is not an option

[...] ays to complete. He and the guide then skied back to the base camp in 12 days, the return trip aided by kites that took advantage of the trailing winds. The others flew back. But it wasn’t that easy. Day after day after day for 53 days seeing [...]

Many Doctors Not Using Colon Cancer Test Properly - BusinessWeek

[...] the fecal immunochemical tests. Those high-sensitivity tests are much more effective at detecting colorectal cancer and advanced lesions. One positive finding was that 93 percent of the physicians said they used colonoscopy as a follow-up to a [...]

New CDC Study Finds Colorectal Cancer Screening Practices Need Improvement

[...] tly lower. The high-sensitivity tests are superior to the standard guaiac-based FOBT in detecting colorectal cancer and advanced lesions. On a positive note, 93 percent of physicians reported using colonoscopy as a follow-up to a positive FOBT, [...]

Research team discovers genetic variance in cancer protection from statin drugs

[...] e, education, research and community service. Weill Cornell physician-scientists have been responsible for many medical advances — including the development of the Pap test for cervical cancer; the synthesis of penicillin; the first succe [...]

CBC NEWS - HIGH RATES OF COLORECTAL CANCER IN P.E.I.

[...] Erbitux or Vectibux and these are for third-stage disease. Each year about 17 or so people on the island who have this advanced case of the disease, we know that this can prolong their life, make them healthier during their period of time when [...]

One Sigmoidoscopy Boosts Colon Cancer Survival Odds

[...] bstantial and long-lasting protection from colorectal cancer," the authors wrote in a study released online April 27 in advance of publication in an upcoming print issue of The Lancet. Colorectal cancer is the third most common cancer worldwide [...]

Five-minute colon cancer test could save thousands

[...] ed the he first, large randomized trial of sigmoidoscopy to prove the test can save lives. It's been released online in advance of publication in The Lancet. Experts say the results suggest that the screening might be an even more effective too [...]

Jodi Wilson -ING Ottawa Half Marathon

[...] e Ottawa Half Marathon to raise money for the Colorectal Cancer Association of Canada. Without funding, we will not see advancements in screening or in funding medications that are not yet accessible in Canada. I'll be proudly running in my dad [...]

No Benefit Adding Cetuximab to Chemo for Stage III Colon Cancer

[...] is difficult to understand how an agent that helps patients with metastatic cancer is not beneficial to those with less advanced disease. At this point we are focusing our efforts on identifying a biological explanation for these findings. He w [...]

Lilly’s Erbitux failed to help patients in study

[...] lts were disclosed Monday at a meeting of the American Society of Clinical Oncology. Erbitux has been proven useful for advanced colon cancer, and is approved for use in colorectal, head and neck tumors. (Star report) [...]

Earlier Colorectal CA Screening for Blacks Advised

[...] of cancers presenting before age 50, and lower screening rates than whites. Black patients also have, in general, more advanced cancer at diagnosis. "There are multiple possible explanations for this phenomenon, including societal issues (such [...]

DNA Mismatch Repair and 5-FU: What’s the Connection?

[...] cells (lymphocytes). Some scientists speculate that it is this improved immune-response that gives them their survival advantage. Daniel Sargent, Ph.D., and his team analyzed mismatch repair status in the tumors of 457 patients in five differe [...]

DNA Test May Speed Colon Cancer Diagnosis

[...] in DNA after Dr. Bert Vogelstein of Johns Hopkins University discovered the series of mutations by which a colon polyp advances to full cancer. But no single mutation predicts a patient’s risk, and the mutation tests, though more accurate th [...]

DNA Test May Speed Colon Cancer Diagnosis

[...] in DNA after Dr. Bert Vogelstein of Johns Hopkins University discovered the series of mutations by which a colon polyp advances to full cancer. But no single mutation predicts a patient’s risk, and the mutation tests, though more accurate th [...]

DiagnoCure hires U.S. dealer for expansion

[...] gion are told that the cancer hasn’t spread, even though it actually has, because current screening measures aren’t advanced enough. To prevent this, DiagnoCure's test looks much deeper into the tissue. [...]

Giant Colon Tour - Winnipeg, Manitoba

[...] and internal hemorrhoids, ulcerative Colitis, Crohn's disease, rectal cancer, various types of polyps, diverticula, and advanced colorectal cancer. The Giant Colon Exhibit is equipped with floor lights and sensors on both sides of the structure [...]

Defective Mismatch Repair in Colon Cancer: A Prognostic Or Predictive Biomarker?

[...] ajority (85%) of stage II patients with pMMR tumors, these new data are not sufficiently strong to offer any compelling advance on the QUASAR (Quick and Simple and Reliable) data.14 There is a considerable effort being undertaken to establish t [...]

Dr. Oz’s despicable adventures in self-promotion

[...] ck? Dr. Oz is 50 years old. The only thing that would have been dumb is Dr. Oz failing to get a colonoscopy despite his advanced medical knowledge. I didn’t have to go to med school to know when to start getting this test – I simply listene [...]

Multivitamins may not slow colon cancer

[...] on cancer recurrence and survival. The team followed more than 1,000 individuals who had recently undergone surgery for advanced (stage III) colon cancer, which, combined with rectal cancer, is the third most diagnosed cancer in both men and wo [...]

75mg Aspirin Daily Reduces Colon Cancer

[...] k redabdominal discomfort or bloatingweight lossextreme fatigue Unfortunately, in many cases colon cancer can be in the advanced stages before it ever gets diagnosed. The most sufficient prevention for this cancer is early detection. Numerous w [...]

Actis Biologics starts phase-III trials of cancer drug

[...] US. The estimated market size for Angiozyme globally is expected to be around USD 15 billion. Due to manufacturing cost advantage, Angiozyme is likely to reduce cancer treatment cost to one-fifth of conventional costs, Active Biologics Presiden [...]

With screening, she caught it

[...] the importance of mammograms, he notes, but colorectal cancer is equally preventable, and, if it's not caught until the advanced stages, is much more deadly. “Both, if caught early, are very, very curable. If you do your diligence, you're goi [...]

With screening, she caught it

[...] the importance of mammograms, he notes, but colorectal cancer is equally preventable, and, if it's not caught until the advanced stages, is much more deadly. “Both, if caught early, are very, very curable. If you do your diligence, you're goi [...]

Fighting the Big C with software

[...] s that improve care and help patients deal with long-term complications like cognitive delays, he said. "One of the big advances of the last decades has been the ability to identify children at lowest risk of their disease recurring. This has a [...]

Ubiquitin D as a novel marker for colorectal cancer prognosis

[...] ificantly associated with depth of cancer invasion, lymph node metastasis, distant metastasis, tumour histologic grade, advanced clinical stage and Ki-67 proliferative index. The researchers note "We found patients with UBD-positive tumours to [...]

Colonoscopy technique increases polyp detection in far reaches of right colon

[...] the further progression to high‐grade dysplasia can be estimated at an additional four years. These polyps appear to advance at a slower rate than conventional adenomas," commented Dr. Genta. Colonoscopy Technique Increases Polyp Detection i [...]

Colonoscopy Technique Increases Polyp Detection In Far Reaches Of Right Colon

[...] the further progression to high‐grade dysplasia can be estimated at an additional four years. These polyps appear to advance at a slower rate than conventional adenomas," commented Dr. Genta. Colonoscopy Technique Increases Polyp Detection i [...]

AJR: CTC may boost colorectal cancer screening compliance

[...] diation dose emitted by CTC, the authors concluded that "on the basis of low doses of radiation delivered with CTC, the advanced age of patients undergoing the examination for screening purposes, the proven performance characteristics of the ex [...]

Exact Sciences Awarded Federal Grant to Support Its Cancer Screening Product Development

[...] py to prevent, detect or treat chronic or acute disease and conditions; reduce long-term health costs; or significantly advance the goal of curing cancer within a 30-year period. More than 140,000 Americans are diagnosed with colorectal cancer [...]

Exact Sciences Awarded Federal Grant to Support Its Cancer Screening Product Development

[...] py to prevent, detect or treat chronic or acute disease and conditions; reduce long-term health costs; or significantly advance the goal of curing cancer within a 30-year period. More than 140,000 Americans are diagnosed with colorectal cancer [...]

Keyhole bowel cancer surgery is safe and effective: Study

[...] copic surgery should now be offered to all patients with colorectal cancer so that they can benefit from the recognised advantages, such as quicker recovery, shorter hospital stay and earlier return to normal function," he added. The research i [...]

Wide Genetic Testing for Lynch Syndrome Cost Effective

[...] t and cure cancer. Founded in 1907, the AACR is the world’s oldest and largest professional organization dedicated to advancing cancer research. The membership includes 32,000 basic, translational and clinical researchers; health care profess [...]

Researchers at Philadelphia conference announce progress toward noninvasive colon cancer test

[...] hat most people do not undergo colonoscopy until they have symptoms such as bleeding - at which point the cancer may be advanced. If forthcoming studies prove successful, the test could increase early detection by making screening less onerous. [...]

Roles reversed; enemy’s the same

[...] the story ended there, it would be a relatively happy one, but it doesn't. Her husband, Joe Marchildon, 47, is fighting advanced colon cancer. Stage four, it has metastasized to his liver. He is being treated at the Royal Victoria Hospital. In [...]

Survival Improved After Colorectal Liver/Lung Mets Resection

[...] r outcome, has been considered a contraindication to resection. More recent studies are challenging this belief, citing advances in systemic chemotherapy and surgical technique as well as improved multidisciplinary management and patient select [...]

Warnex Launches Septin9 Blood Testing Service for Colorectal Cancer in Canada

[...] st based on real-time PCR technology to our service offering as part of our continued commitment to delivering the most advanced specialized diagnostic services to Canadian healthcare professionals," said Mark Busgang, President and CEO of Warn [...]

10 Recent Studies and Breakthroughs Impacting Gastroenterology/Endoscopy

[...] th a family or past history of colorectal cancer should be tested between colonoscopies in order to help detect CRC and advanced tumors that are either missed or develop rapidly. Using fecal occult blood tests at regular internals between colon [...]

Why Screening for Colorectal Cancer Shouldn’t Be a Hard Sell

[...] ts older than 50 is overdue for a colorectal cancer screening. As a result, patients may suffer and die needlessly from advanced cancers that, having spread to other organs, offer little hope of survival. Colon Screening: 5 Things You Need to K [...]

Colorectal Cancer Drug Futures - new market report published

[...] chemotherapy is the mainstay of CRC treatment the use of targeted therapies are gaining acceptance in the treatment of advanced disease. This trend is expected to continue as new combinations are evaluated and therapies are increasingly used i [...]

Excercise ups survival for cancer patients

[...] e men engaged in a variety of different recreational exercises. The benefit of exercise was seen regardless of age, how advanced the cancer, weight and any history of previous physical activity. The findings are published in Archives of Interna [...]

Immunochemical Fecal Testing Speeds Cancer Detection

[...] (63 percent sensitivity). Compared to colonoscopy alone, the cancers were detected a median of 25 months earlier, while advanced adenomas were detected a median of 24 months earlier. "Interval FIT testing in a high-risk colonoscopy surveillance [...]

Treatment-Related Mortality With Bevacizumab in Cancer Patients - A Meta-analysis

[...] CIs) were calculated using fixed- or random-effects models. Data Synthesis A total of 10 217 patients with a variety of advanced solid tumors from 16 RCTs were included in the analysis. The overall incidence of FAEs with bevacizumab was 2.5% (9 [...]

UNC to lead study of new option for some colon cancer patients

[...] iate director for clinical research at UNC Lineberger. “This trial is exciting because it provides another option for advanced disease, the standard chemotherapy regiment plus a new agent called regorafenib.” According to Goldberg, this is [...]

The best defence

[...] ges, this cancer is asymptomatic and by the time people experience a symptom, like rectal bleeding, the cancer is often advanced," says Anderson. "In Ontario, there are 8,300 new cases of colorectal cancer every year and almost half of those pe [...]

Colon screening waits can be up to 3 years

[...] sing cancer and/or a false negative result, so that a cancer or precursor to cancer goes undetected until it reaches an advanced stage," she said. "Colonoscopy is the best available test by a significant margin for early detection and treatment [...]

Racial Disparities Still Exist in Colorectal Cancer Screening Despite Increased Medicare Coverage

[...] t and cure cancer. Founded in 1907, the AACR is the world’s oldest and largest professional organization dedicated to advancing cancer research. The membership includes 33,000 basic, translational and clinical researchers; health care profess [...]

Given Imaging Announces Positive Results From European Multicenter Study of Second-Generation PillCam® COLON

[...] ery of the Alimentary Tract. The meeting showcases approximately 5,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. For more information, visit www.ddw.org. About PillCam COLON 2 The PillCam [...]

Chemo drug shortage leaves hospitals scrambling

[...] olves more paperwork and extra costs, and applies only in exceptional cases. Doctors and pharmacists are clamouring for advance notice of shortages through a central registry, as exists in the U.S. A registry wouldn't solve the supply problems, [...]

Not enough Canadians being screened for colorectal cancer, leading to many unnecessary deaths

[...] ively launch province-wide screening programs in 2007 and 2008 respectively). Conclusions and recommendations Treatment advances and screening have led to important reductions in colorectal cancer deaths and improvements in survival. However, f [...]

ONTARIO CONTINUES STRONG CANCER PERFORMANCE

[...] ar's CSQI report found that the increase in the colorectal cancer survival rate is due to improvements in screening and advancements in treatment. It also identified the need for a fuller integration of cancer services to address challenges rel [...]

Most cancer patients like full access to records

[...] note in the journal Cancer. But Dave deBronkart, a prominent blogger on patient involvement since his own recovery from advanced kidney cancer, argues that full access is helpful. deBronkart, who blogs as "e-patient Dave," told Reuters Health b [...]

Dr. Oz Highlights the Importance of Following Bowel Preparation Instructions Before Colonoscopy

[...] Endoscopy Since its founding in 1941, the American Society for Gastrointestinal Endoscopy (ASGE) has been dedicated to advancing patient care and digestive health by promoting excellence in gastrointestinal endoscopy. ASGE, with nearly 12,000 [...]

Cancer Care Ontario and eHealth Ontario Partner to Deliver Safer Chemotherapy Treatment

[...] cancer patients are getting the safest and most effective treatment possible is vitally important. This investment will advance chemotherapy treatment standards and help CCO track data so that, together, we can plan to improve cancer care acros [...]

Breast Cancer Drug for Colon Cancer?

[...] ost exciting result, to be able to provide a molecular rationale for a new treatment combination for difficult-to-treat advanced colorectal cancers." This new combination treatment is ready for clinical trials, according to the researchers. The [...]

Macho men less concerned about their own health

[...] h care. They say the findings help explain why men, on average, don't live as long as women despite their socioeconomic advantage. "The stereotype that real men don't get sick and that real men's bodies are impervious to harm is ironic because [...]

New chemotherapy scheduling system gives patients more notice of appointments

[...] ng treatment for breast cancer. He says many patients were being notified of their appointments as little as one day in advance, but now the number of patients who get less than a week's notice has been cut by 58 per cent. Chemo SmartBook, whic [...]

New Technique to Remove Large Colon Polyps, California First

[...] With the use of this new surgical platform, we can now offer patients an innovative, less invasive procedure to remove advanced polyps with significantly less pain and scarring compared to the standard surgical procedure,” said McLemore, col [...]

Canada Signs UN Declaration on Preventing and Controlling Chronic Diseases

[...] nt investments in health research in recent years have enabled Canada to capitalize on important health discoveries and advances in knowledge. Through these investments, Canada has secured a place on the global stage in such areas as HIV/AIDS, [...]

Touring a giant colon in Oshawa

[...] le stated. If detected early through screening, there's a 90-per cent chance of being cured. However, if detected in an advanced stage, there's only a 10-per cent chance of survival. More than 90 per cent of people who get colon cancer are 50 o [...]

Colorectal cancer on the rise in adults under 50

[...] II or IV, with stage IV being the most severe grade of the disease. Other factors that increased the risk for having an advanced cancer at diagnosis were being African-American or lacking health insurance. "It's cause for concern," says Siegel, [...]

Chocolate shown to protect against colon cancer

[...] dy eliminates old, unhealthy cells, to make way for new ones - a "chemoprevention mechanism" that helps ward off cancer advancement. For eight weeks, researchers fed rats a cocoa-rich diet - 12% - and then induced the effects of cancer. Results [...]

COLORECTAL CANCER SCREENING NOW AVAILABLE THROUGHOUT THE NORTH

[...] ch is why we are pleased to expand this program with the help of the northern health regions.” The Agency will use an advanced fecal immunochemical test (FIT) to screen participants who are between the ages of 50 and 74. The test will be mail [...]

The Daily Checkup: Screenings provide the best early warning against colorectal cancer

[...] of the most difficult things about treating colorectal cancer is that it usually remains asymptomatic until it is quite advanced. “For most patients, the number 1, 2 and 3 symptom is no symptom at all,” says Itzkowitz. “A little polyp is [...]

Largest Comparative Study of Radioembolisation Shows SIR-Spheres Microspheres Significantly Improves Survival for Cancer Patients with Inoperable Liver Tumours

[...] reatment or continued supportive care," explained Prof Bester. "This group was unlikely to represent patients with more advanced disease and was consequently used as a standard-care comparison cohort." References: Saxena A, Chua TC, Meteling B [...]

N.S. woman urges using colon cancer screening kit

[...] d her test kit late last year, but didn't decide to use it until a few months ago. She wants more Nova Scotians to take advantage of the potentially life saving program. "I feel anybody who receives the kits should certainly take the samples an [...]

UICC World Cancer Congress 2012

[...] o you don't miss out on discounted rates. All Congress attendees must register online for the event. Delegates can take advantage of reduced rates by registering before 22 April 2012. [...]

Colorectal cancer test adherence can vary by race/ethnicity, treatment options offered

[...] ore likely to complete screening than white participants. Other factors associated with adherence to screening included advanced age, possession of health insurance and language preference. Participants whose interviews were conducted in Spanis [...]

Stem cells hold clues for colon cancer

[...] mouse models to develop tumors in section of the intestines where most human tumors develop: the colon. One additional advantage of this model, in contrast to others, is that the tumors develop quickly and can be easily monitored with endoscop [...]

Cancer an increasing concern for youth

[...] surveyed and led researchers to conclude that Emiratis with colorectal cancer do present at a relatively young age with advanced stages of the disease - indicating that the disease has struck the victims even earlier in life. They have suggeste [...]

Wonder Drug for Colon Cancer?

[...] are not well enough to have chemotherapy. Bowel cancer is more common in older people, so these results could be a big advance in treatment of the disease, particularly in this group. But we need further research to confirm this,” Liefers co [...]

A brand new day in cancer treatment

[...] ision is that five to 10 years from now this will be part of routine clinical practice." At the same time as diagnostic advances are taking place, on the therapeutic side the move to personalized medicine has also led to a significant shift awa [...]

Statins ’could halve cancer risk’

[...] e study follows a UK trial which is investigating whether a curry ingredient can improve the treatment of patients with advanced bowel cancer. Scientists are to supplement standard chemotherapy with pills containing curcumin, a compound found i [...]

The Laxative-Free ’Virtual Colonoscopy’

[...] ted to have a conventional colonoscopy, the other a laxative-free virtual colonoscopy. While colonoscopy picked up more advanced abnormal growths, a higher percentage of people invited to have CT colonography agreed to be screened. Virtual Colo [...]

Colon Cancer Challenge Foundation Gets Fit to Be Tied for Father’s Day

[...] th a family history of colon cancer.Talk to your doctor.Get screened. "Colorectal cancer can be highly treatable due to advances in screening and detection procedures," said Dr. Thomas K. Weber, MD, FACS, President of the Colon Cancer Challenge [...]

Bedford Laboratories™ Issues Nationwide Voluntary Hospital/User-Level Recall Of Leucovorin Calcium Injection

[...] asible; and for use in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. Notification of the Leucovorin Calcium lots listed above is being sent to customers who have rec [...]

Edmonton Patient Information Session Nov. 4

[...] and caregivers at the Cross Cancer Institute. The experts highlighted the standards of care in the medical treatment of advanced colorectal cancer by bringing to the forefront the integration of personalized medicine and the biological treatmen [...]

M.I.S. In The Management of Colon & Rectal Cancer - April, 18, 2012

[...] M.I.S. In The Management of Colon & Rectal Cancer - April, 18, 2012 To advance education and awareness of Minimally Invasive Surgery (MIS) within the Canadian surgical community and the public, t [...]

Colorectal cancer screening program expands

[...] ed to do - save lives by detecting cancer in its early stages," Livingstone said in a news release. The agency sends an advanced fecal immunochemical test (FIT) to selected participants who complete the test in the privacy of their homes. Based [...]

The test that can save your life

[...] l were admitted in an emergency situation - much higher than the rates of six to 34 per cent seen in other studies. The advanced age of the general Vernon population and the lack of an effective provincial colorectal cancer screening program in [...]

The test that can save your life

[...] l were admitted in an emergency situation - much higher than the rates of six to 34 per cent seen in other studies. The advanced age of the general Vernon population and the lack of an effective provincial colorectal cancer screening program in [...]

More younger people getting colorectal cancer

[...] ter their age," she said. When it is finally diagnosed, the cancer in younger patients has usually progressed to a more advanced stage, making it more complicated and costly to treat, doctors said. Dr. Laura Porter was diagnosed with stage 4 ca [...]

Eastern Health Goes Live with NexJ Disease Screening

[...] the number of instances of early detection and, as a result, reduce the number of deaths from the disease. "Introducing advanced automation to disease screening programs not only improves efficiency, it enhances reliability and usefulness of th [...]

My Semicolon Life: It’s not just your cancer

[...] gularly for gynecological cancers, most likely using a combination of ultrasounds and biopsies. Barring a major medical advance, their doctors may recommend preemptive hysterectomies when they reach their 30s. There's a pretty good chance I'll [...]

U of M researchers: Newly discovered genetic markers could signal colon cancer development

[...] boy, an M.D./Ph.D. student studying at the University of Minnesota, worked closely on this project and is nowworking to advance the science of this paper to the next stage. What were finding is that tumors may look the same, but theyre fundamen [...]

New Prep for Colon Screen Uses Four Pills, Not Liquid Laxative

[...] dy. Greenwald, a spokesman for the American Society for Gastrointestinal Endoscopy, also said that a colonoscopy has an advantage over a colonography in that any identified polyp can be removed right then without having to undergo a secondary p [...]

Quebecers urged to continue to be screened for colon cancer despite recent events concerning incomplete examinations

[...] y for a cure as colon cancer is 90 % curable when found in its early stages. For any patient that is found to have more advanced disease the prognosis is better than ever, however the challenges are indeed much greater. It is therefore extremel [...]

Potential New Colorectal Cancer Treatment Target Identified

[...] lts tumor growth when silenced, according to research published online Oct. 1 in Cancer. Marica Gemei, Ph.D., of CEINGE-Advanced Biotechnology in Naples, Italy, and colleagues characterized CD66c expression in colorectal cancer stem cells by fl [...]

Kinder, gentler test for colon cancer

[...] he cost and the risk the patient will pick up an infection. Plummer's cancer was at an early stage. If it had been more advanced and the risk of spread to the lymph nodes had been greater, it would not have been the right approach, experts say. [...]

Hay Fever, Asthma Combination Linked to Lower Risk for Death From Colorectal Cancer

[...] erican Association for Cancer Research (AACR) is the world’s first and largest professional organization dedicated to advancing cancer research and its mission to prevent and cure cancer. AACR membership includes more than 34,000 laboratory, [...]

Race, Income Tied to Late Colon Cancer Diagnoses, Study Finds

[...] For the study, the researchers analyzed national data collected between 1992 and 2005 on adults aged 66 and older with advanced colon cancer. Of the nearly 89,000 patients identified, 29 percent were diagnosed following an emergency. Of these, [...]

AACR: New noninvasive colorectal CA screen promising

[...] 98% of all cancers as well as 83% of precursors with high-grade dysplasia and 57% of precursors 1 cm or larger overall (advanced adenoma or sessile serrate adenoma), at 90% nominal specificity. "We are encouraged by the results of this study fo [...]

Calories poorly grasped for maintaining weight

[...] ineffective." Last month, McDonald's in the U.S. announced it will unveil menu board labels in American restaurants in advance of the U.S. federal regulations. "With regard to nutrition information in restaurants the conversation has progresse [...]

Tired after cancer treatment? Walking may help

[...] atigue during or after treatment (see Reuters Health story of October 29, 2012). But light-to-moderate exercise has the advantage of being something people can do on their own time, for little or no cost. "We're not expecting people to go out a [...]

Tired after cancer treatment? Walking may help

[...] atigue during or after treatment (see Reuters Health story of October 29, 2012). But light-to-moderate exercise has the advantage of being something people can do on their own time, for little or no cost. "We're not expecting people to go out a [...]

ERBITUX® in combination with chemotherapy approved in Canada as initial treatment of patients with metastatic colorectal cancer

[...] nografts lacking EGFR expression. Erbitux is also approved in Canada for the initial treatment of locally or regionally advanced squamous cell carcinoma of the head and neck in combination with radiation therapy. SOURCE: Bristol-Myers Squibb Ca [...]

CCAC Live Interview

[...] Lisa Blobstein was just 36 years old and a new mom when her husband was diagnosed with advanced colon cancer. Her 38 year old husband Steve lost his heroic battle in June 2011. Their son AJ was just 17 months ol [...]

MARCH IS COLORECTAL CANCER AWARENESS MONTH – MYTHS, FACTS, AND WHAT YOUR HEALTH MINISTER HAS TO SAY

[...] , anemia or constant tiredness can all signal colon cancer. Once the symptoms start to develop it may be a sign of more advanced disease,” he emphasized. Myths & Facts Myth - Colorectal cancer is a man’s disease. Truth - Colorectal canc [...]

Roche study reports that Avastin plus Xeloda helped elderly people with metastatic colorectal cancer live four months longer without their disease worsening

[...] ally well tolerated and the safety profile was consistent with previously reported data in mCRC. “Older patients with advanced colorectal cancer have often been left without treatment purely based on their age. The results of this study open [...]

Selon une étude de Roche, Avastin en association avec Xeloda a permis aux personnes âgées atteintes d’un cancer colorectal métastatique de vivre quatre mois de plus sans que leur maladie s’aggrave

[...] col 2009;27(2):199-205. 4 - Price TJ et al. Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: a subgroup analysis from the AGITG MAX trial: an international randomised controlled trial of Ca [...]

First New Colon Cancer Treatment Since 2006 Received Priority Review From Health Canada And Is Now Approved For Canadian Patients With Metastatic Colorectal Cancer

[...] giogenesis, oncogenesis and the tumour microenvironment.ii “New treatment options offer hope for patients living with advanced disease and highlight the oncology community’s ongoing commitment to patients offering not only the opportunity t [...]

Minimally Invasive Surgery for Treatment of Colorectal Cancer Yields Optimal Outcomes for Patients

[...] ient Information Guidelines for Laparoscopic Colon Resection” for those undergoing cancer treatment, highlighting the advantages of minimally invasive procedures and other pertinent information. “Early screening is key to prevention, and it [...]

ASGE Releases Special Journal for Colorectal-Cancer Awareness Month

[...] delines, an expert consensus opinion was separately published in 2012 based on an expert panel discussion and review of advancements and insights in the serrated polyp literature. The 2012 guidelines have placed serrated polyps >10 mm or with c [...]

Support for principles to guide health care transformation in Canada continues to build

[...] ient advocacy groups and key cancer control stakeholders across Canada, CCAN is grounded in the belief that in order to advance efforts to achieve universal and timely access to quality care and treatment, a patient-centred approach must be fir [...]

B.C.’s colon cancer screening program moves forward

[...] es that family physicians have a strong role in the screening patient pathway. "As a colorectal cancer survivor who had advanced disease, I underwent years of treatment and many surgeries. I have no evidence of the disease today, however, had m [...]

B.C.’s colon cancer screening program moves forward

[...] es that family physicians have a strong role in the screening patient pathway. "As a colorectal cancer survivor who had advanced disease, I underwent years of treatment and many surgeries. I have no evidence of the disease today, however, had m [...]

The molecular revolution - an article from Cancer Research UK

[...] same time we need to make some fundamental adjustments to the ways in which trials are organised if we are to take full advantage of our new knowledge. Peter Johnson Chief Clinician Cancer Research UK www.cancerresearchuk.org [...]

More younger people getting colorectal cancer

[...] ter their age," she said. When it is finally diagnosed, the cancer in younger patients has usually progressed to a more advanced stage, making it more complicated and costly to treat, doctors said. Dr. Laura Porter was diagnosed with stage 4 ca [...]

ASCO: Fitness at 50 Linked to Less Cancer Risk

[...] ected — a lower risk of dying from cardiovascular causes, Lakoski told reporters in a telephone press briefing in advance of the 2013 meeting in Chicago of the American Society of Clinical Oncology. But the effects of fitness on cancer ri [...]

Novel RNA-based classification system for colorectal cancer

[...] tal cancer) is the third most common cancer in men and the second most common cancer in women worldwide. Despite recent advances in the screening, diagnosis, and treatment of colorectal cancer, an estimated 608,000 people die every year from th [...]

Cancer-surgery wait times longest in Montreal

[...] ation of panic,” said Barry Stein, President of the Colorectal Cancer Association of Canada. Stein was diagnosed with advanced colorectal cancer back in 1996 and he opted for surgery in the United States after being told he would have to wait [...]

New study could help increase survival rates of people with colorectal tumours

[...] ave a good survival rate - 90 per cent after five years - but this figure drops to 68 per cent for those detected at an advanced stage and just 10 per cent when it has spread to other parts of the body. In the United Kingdom it is the second mo [...]

Dr. Ruff Analyzes Overall Survival in the VELOUR Trial

[...] is equivalent to an approximate 18% reduction in the risk of dying, Ruff explains. Furthermore, Ruff adds, the survival advantage with aflibercept appears to be sustained over the course of the trial. At 18 months, aflibercept increased surviva [...]

Cancer Survivors to Celebrate Life on National Cancer Survivors Day – Sunday, June 2, 2013

[...] increased public awareness are needed to improve the quality of life of cancer survivors,” says Shipp. “Because of advances in modern medicine, cancer survivors are now living much longer after diagnosis. However, long-term survivorship po [...]

Vancouver Scotia bank Half-Marathon & 5K

[...] rticipants to walk or run on our behalf! If you are interested please email us at elyseb@colorectal-cancer.ca Thanks in advance for your support! http://www.canadarunningseries.com/svhm/ [...]

MET Protein May Be Biomarker for Aggressive Colon Cancer

[...] sonalized cancer diagnosis and treatment. “While we know there are many of types of colorectal cancer, we’re not as advanced as we’d like to be in our understanding of them," said Scott Kopetz, MD, PhD, associate professor in MD Anderson [...]

Accord Aims to Create Trove of Genetic Data

[...] genetic and clinical data about people and how they respond to treatments will be hopelessly fragmented and impede the advance of medical science. This ambitious effort hopes to standardize the data and make them widely availabl e. “We are s [...]

Tumor Features Predict Colon Blockage

[...] ble to distinguish between malignant and benign causes for the bowel obstructions. This can't always be done, even with advanced imaging techniques, but can provide important information in decisions about treatment, the researchers noted. In a [...]

Studies Show Cancer Survivors’ Physical and Emotional Problems Often Go Untreated

[...] vors report poor physical health and 1 in 10 cancer survivors report poor mental health. In one study of 163 women with advanced breast cancer, 92% had one or more physical impairment, but fewer than 30% received rehabilitation care. Another st [...]

Too young for colon cancer? Think again

[...] tionwide problem. He's treated patients as young as 17 years old. Patients, like Josh, are fighting more aggressive and advanced forms of the disease. Those in their 40's concern him the most. "The numbers doubled. In other words, there was a 1 [...]

As top court invalidates some gene patents, biotech has moved on

[...] r lucrative new DNA-based product that remains untouched by the Court decision is called "companion diagnostic." Recent advances in cancer treatment have come from drugs that target a genetic mutation that fuels the malignancy. Because the drug [...]

Venter and Topol on the True Revolution in Medicine

[...] medicine. Fortunately, as you know, we've had a huge technology change in the past decade — not a lot of genomic advances but a lot of technology changes. We had a giant building filled with 300 sequencing machines that sequenced the hum [...]

Another clue to how the naked mole rat stays cancer free

[...] ng way to go before we fully understand it. And it may even be something tumours can, on occasion, subvert to their own advantage. For example, it seems that the high levels produced by pancreatic tumours protect it from chemotherapy. Much like [...]

Sugar Makes Cancer Light-Up in MRI Scanners

[...] umours to appear as bright images on MRI scans of mice. Lead researcher Dr Simon Walker-Samuel, from the UCL Centre for Advanced Biomedical Imaging (CABI) said: "GlucoCEST uses radio waves to magnetically label glucose in the body. This can the [...]

Speed up colon-screening tests, B.C. health minister urges

[...] screening program is to reduce the number of people who show up in hospital emergency departments with urgent cases of advanced colorectal cancer. Colorectal cancer is the second-leading cause of cancer death in adults after lung cancer. The n [...]

What is the biggest mistake patients make?

[...] us, we shouldn’t automatically dismiss his advice if it runs counter to our inclinations, for doctors have a crucial advantage over the patients for whom they care: the ability to think dispassionately about the choices their patients must f [...]

Cancer Research UK appoints Guerilla Tea to build world first mobile phone game to seek cures

[...] based on their genetic fingerprint – but this research produces terabytes upon petabytes of data requiring analysis. Advances in technology help our scientists identify new causes and drivers of cancer, but much of the data must be analysed [...]

Colonoscopies wrong for 8 Lakeshore Hospital patients

[...] he president of the Colorectal Cancer Association of Canada. However, he said, what isn’t yet known is whether it’s advanced or early-stage cancers. “We don’t know what the stage is of those malignancies. Were these cancers that started [...]

Colorectal Cancer & Personalized Medicine Montreal, November 5-6 2013

[...] 13, to promote a better understanding of how medicine and society are preparing for a new age in cancer treatment. With advances in technology and a progressive understanding of cancer biology, personalized medicine is being applied in cancer d [...]

Colon Cancer Screening Tests Work, Studies Report

[...] sitive, so we would expect the benefit to be even greater today with that test." The blood test may have some potential advantages over colonoscopy, Levin added. Patients have to undergo an uncomfortable cleansing process prior to a colonoscopy [...]

Active seniors more likely to ’age successfully’

[...] is study supports public health initiatives designed to engage older adults in physical activity, even those who are of advanced age." Participants who took up activity were also more likely to remain healthy compared with those who continued t [...]

New agency looks to make cancer drug funding decisions more reasoned, less emotional for provincial governments

[...] t benefits of pricey new treatments. It recently was criticized for rejecting funding for a drug that extended life for advanced colorectal cancer patients by 1.4 months on average, but even that “could mean a very big difference” for some [...]

Post-Surgical Tests Might Help Spot Colon Cancer’s Return

[...] eived another surgery to treat a cancer recurrence. People who received both CEA testing and a CT scan did not have any advantage in cancer detection, with 6.6 percent receiving additional surgery for recurring cancer. However, this doesn't mea [...]

Budgets for cancer care in Montreal hospitals to be cut, health minister confirms

[...] tients would like to be treated near their homes, but the fact of the matter is that when you have cancer, particularly advanced cancer that requires a certain expertise, you have to come to the island of Montreal where you can get that special [...]

Bayer kicks off Ph III Stivarga trial in colorectal cancer patients

[...] hemotherapy, an anti-VEGF therapy, and, if KRAS wild type, an anti-EGFR therapy; and and to treat patients with locally advanced, unresectable or metastatic gastrointestinal stromal tumour (GIST) who have been previously treated with imatinib m [...]

The Latest Findings on Supplements and Cancer Risk

[...] Another study focused on selenium and vitamin E supplements, finding that high-doses of both increases the risk of the advanced form of prostate cancer. The increased risk from each supplement depends upon whether men start out with relatively [...]

Couillard opposes plan to curb access to Montreal’s cancer centres

[...] restriction is probably illegal,” he said. Stein said patients requiring radiation therapy probably have some sort of advanced cancer and, under those circumstances, would want to choose the best place in the province to get treatment. “If [...]

NICE and SMC decisions on use of aflibercept (Zaltrap) in the NHS

[...] nd has already been made available through the Cancer Drugs Fund to patients in England. It is vital that patients with advanced bowel cancer are able to access treatment based on clinical need rather than their UK postcode." On 10 March 2014 t [...]

The Dreaded Turning-50 Test

[...] of surgery at the University of Minnesota, had concerns about the DNA test finding only 42 percent of polyps. The great advantage of colonoscopy, he said, was its ability to prevent cancer entirely by finding these growths so that they could be [...]

Surgery for rectal cancer

[...] researched. It involves the use of a robot controlled by the surgeon to perform more difficult procedures. Surgery for advanced rectal cancer Sometimes the cancer is too large to be removed and presses on the rectum, causing it to narrow. If t [...]

Obesity May Shorten Colon Cancer Survival

[...] the American Association for Cancer Research in San Diego. "Now that we have seen that obesity attenuates the survival advantage observed for patients with MSI-high tumors, we are looking at how it affects other tumor markers that have relevan [...]

Interesting new Trial for Stage lll resected CRC FOLFOX and CELEBREX®

[...] other parts of the body. For early-stage disease, surgery alone may be sufficient to eradicate the cancer, but for more advanced stage III colon cancer, the use of chemotherapy after surgery (adjuvant chemotherapy) may help prevent or delay the [...]